Abstract: A manifold adaptor plate useful as a gasket having liquid pathways which permit passing of a filtrate, a feed and a retentate wherein admixture of the filtrate with the feed or the retentate is prevented is provided and is formed of an elastomeric layer, a rigid intermediate layer and a polymer layer. The elastomeric layer functions as a gasket and is bonded to the polymeric layer through the liquid pathways of the intermediate plate. An elastomer layer may be formed on both layers as well and optionally a second polymer layer between the intermediate layer and the second elastomer layer may also be used.

Abstract: A spiral wound filtration cartridge construction is provided which includes a cartridge positioned within a solid outer cylinder which, in turn is positioned within a solid outer cylinder which, in turn is positioned within a solid housing. Fluid flows within the space between the outer cylinder and housing is controlled by a ring and flexible chevron construction. The chevron construction includes outer peripheral holes, the sizes and number of which are set to determine by-pass flow.

Abstract: The present invention provides methods for producing single and multi-layered coiled hollow fiber bundles for use in separation modules whose performance can be predicted, said modules being designed to take advantage of the benefits of Dean vortices. The present invention is also directed to multi-layered coiled hollow fiber bundles for use in separation modules that are directly scalable because each layer performs substantially equivalently to the other layers when subjected to a fluid of a certain velocity such that Dean vortices are created.

Abstract: A spiral wound filtration cartridge construction is provided which includes a cartridge positioned within a solid outer cylinder which, in turn is positioned within a solid outer cylinder which, in turn is positioned within a solid housing. Fluid flows within the space between the outer cylinder and housing is controlled by a ring and flexible chevron construction. The chevron construction includes outer peripheral holes, the sizes and number of which are set to determine by-pass flow.

Abstract: A spriral wound filtration cartridge construction is provided which includes a cartridge positioned within a solid outer cylinder which, in turn is positioned within a solid outer cylinder which, in turn is positioned within a solid housing. Fluid flows within the space between the outer cylinder and housing is controlled by a ring and flexible chevron construction. The chevron construction includes outer peripheral holes, the sizes and number of which are set to determine by-pass flow.