Abstract: The invention relates to an in-utero ventriculoamniotic shunting device that includes a shunt tube (26) composed of polymer composite and having metallic wire embedded therein, one or more anchors (30) composed of superelastic wire, e.g., thermal shape-set nitinol structures, that are mechanically attached to an exterior surface of the shunt tube (26), and a one-way passive valve (32) composed of a thin polymer membrane. The anchors (30) are effective to prevent migration and dislodgement of the shunting device following its deployment, and the valve (32) is effective to prevent the backflow of amniotic fluid (23).

Abstract: The invention relates to an in-utero ventriculoamniotic shunting device that includes a shunt tube (26) composed of polymer composite and having metallic wire embedded therein, one or more anchors (30) composed of superelastic wire, e.g., thermal shape-set nitinol structures, that are mechanically attached to an exterior surface of the shunt tube (26), and a one-way passive valve (32) composed of a thin polymer membrane. The anchors (30) are effective to prevent migration and dislodgement of the shunting device following its deployment, and the valve (32) is effective to prevent the backflow of amniotic fluid (23).

Abstract: A fluid container comprises at least two fluid dispensing paths, wherein the fluid container comprises a container body and a fluid dispenser, and the fluid dispenser comprises a dispenser body connected to the container and a bottom portion enclosing the container. The dispenser body comprises a flow path extending through the bottom portion to a flow path exit, and a conduit aperture extending through the bottom portion and configured to accept a flexible conduit therein. A dispenser cap is operably connected to the dispenser body, wherein the dispenser cap comprises a fluid pump configured to pump fluid from the container via the flexible conduit. The dispenser cap is operable between a closed configuration in which the flow path exit is sealed and an open configuration in which the flow path exit is open, enabling fluid to flow out of the container via the flow path.

Abstract: Various embodiments are directed to a fluid container comprising at least two fluid dispensing paths, wherein the fluid container comprises a container body and a fluid dispenser, wherein the fluid dispenser comprises a dispenser body connected to the container and a bottom portion enclosing the container. The dispenser body comprises a flow path extending through the bottom portion to a flow path exit, and a conduit aperture extending through the bottom portion and configured to accept a flexible conduit therein. A dispenser cap is operably connected to the dispenser body, wherein the dispenser cap comprises a fluid pump configured to pump fluid from the container via the flexible conduit. The dispenser cap is operable between a closed configuration in which the flow path exit is sealed and an open configuration in which the flow path exit is open, enabling fluid to flow out of the container via the flow path.

Abstract: Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies.

Abstract: An apparatus and method are disclosed for eliminating the chemical energy of fuel remaining in a fuel cell generator when the electrical power output of the fuel cell generator is terminated. During a generator shut down condition, electrically resistive elements are automatically connected across the fuel cell generator terminals in order to draw current, thereby depleting the fuel inventory in the generator. The invention provides a safety function in eliminating the fuel energy, and also provides protection to the fuel cell stack by eliminating overheating.

Abstract: A mechanism which manages variable length instructions in cache is comprised of three cooperating elements designed to optimize self modifying code and anticipate next instructions for branch operand management. A content addressable memory (CAM) stores addresses of lines which have been accessed for instruction fetching. In a system having modifiable instruction stream (i.e., store to instruction stream), when the CAM matches, the system must retire certain instructions, flush instructions and then fetch the modified instruction stream. Boundary identification logic examines a field in each cache byte to determine the nature of the byte. This field is initially cleared at the time the cache line is loaded and filled with the line is fetched. An anticipation buffer designed to minimize the circuitry necessary for fetches across cache lines is loaded with sequentially anticipated prefetched instructions from the cache. These anticipated instructions can then be concatenated by a fetch aligner.

Abstract: A mechanism which manages variable length instructions in cache is comprised of three cooperating elements designed to optimize self modifying code and anticipate next instructions for branch operand management. A content addressable memory (CAM) stores addresses of lines which have been accessed for instruction fetching. In a system having modifiable instruction stream (i.e., store to instruction stream), when the CAM matches, the system must retire certain instructions, flush instructions and then fetch the modified instruction stream. Boundary identification logic examines a field in each cache byte to determine the nature of the byte. This field is initially cleared at the time the cache line is loaded and filled with the line is fetched. An anticipation buffer designed to minimize the circuitry necessary for fetches across cache lines is loaded with sequentially anticipated prefetched instructions from the cache. These anticipated instructions can then be concatenated by a fetch aligner.