Patents by Inventor Stephen F. Flaim

Stephen F. Flaim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treating Disorders Associated with Inflammation
    Publication number: 20080195024
    Abstract: Methods and apparatuses for treating or preventing disorders related to inflammation are provided. In the methods and apparatuses, a glass fiber filter or other filter is used to remove mediators of inflammation from a bodily fluid.
    Type: Application
    Filed: January 22, 2008
    Publication date: August 14, 2008
    Inventors: Geert W. Schmid-Schonbein, Daniel Fainman, Stephen F. Flaim, Wyming Lee Pang, Alexander H. Penn
  • Amelioration of ischemic damage using synthetic oxygen carriers
    Patent number: 6679859
    Abstract: A method of ameliorating tissue damage resulting from hypoxia or ischemia by administering systemically a synthetic oxygen carrier to an individual having or suspected of having blood vessel obstruction is disclosed. A synthetic oxygen carrier in a physiologically acceptable vehicle, wherein the synthetic oxygen carrier comprises submicron sized particles capable of passing through emboli-obstructed blood vessels is also disclosed.
    Type: Grant
    Filed: July 31, 2000
    Date of Patent: January 20, 2004
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Peter E. Keipert, N. Simon Faithfull, Stephen F. Flaim, Gwen H. Rosenberg
  • Pyruvate derivatives
    Publication number: 20030013656
    Abstract: Certain known and novel pyruvate derivatives are particularly active in restoring or preserving metabolic integrity in oxidatively competent cells that have been subjected to oxygen deprivation. These pyruvate-derived compounds include, but are not limited to oximes, amides, pyruvate analogues, modified pyruvate analogues, esters of pyruvate (e.g., polyol-pyruvate esters, pyruvate thioesters, glycerol-pyruvate esters and dihydroxyacetone-pyruvate esters). Such pyruvate derivatives (including single tautomers, single stereoisomers and mixtures of tautomers and/or stereoisomers, and the pharmaceutically acceptable salts thereof) are useful in the manufacture of pharmaceutical compositions for treating a number of conditions characterized by oxidative stress.
    Type: Application
    Filed: May 3, 2002
    Publication date: January 16, 2003
    Inventors: Bing Wang, Guy Miller, Stephen F. Flaim, Ughetta Del Balzo, Wei Zhang, Satyanarayana Janagani, Jiangao Song
  • Fluorocarbons as anti-inflammatory agents
    Patent number: 5733939
    Abstract: A method for reducing the inflammatory response in tissues of a patient, by contacting the tissue with an effective, inflammation-reducing amount of a liquid or gaseous fluorocarbon.
    Type: Grant
    Filed: November 22, 1995
    Date of Patent: March 31, 1998
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Bradley Phillip Fuhrman, Stephen F. Flaim, Lynn Joanne Hernan, Frances Darey Nesti, Michele Cecile Papo, David Marc Steinhorn
  • Liquid fluorocarbon emulsion as a vascular nitric oxide reservoir
    Patent number: 5726209
    Abstract: Biocompatible fluorocarbon emulsions are utilized to inhibit the removal of endogenously produced nitric oxide from the bloodstream, and to thereby inhibit vascular stenosis, vasoconstriction, and any other physiological condition or disorder arising in whole or in part from a deficiency of endogenous nitric oxide.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 10, 1998
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Stephen F. Flaim, Jean G. Riess
  • Fluorocarbons as anti-inflammatory agents
    Patent number: 5470885
    Abstract: A method for reducing the inflammatory response in tissue of a patient, by contacting the tissue with an effective, inflammation-reducing amount of a liquid or gaseous fluorocarbon.
    Type: Grant
    Filed: September 29, 1993
    Date of Patent: November 28, 1995
    Assignee: The Research Foundation of the State University of New York
    Inventors: Bradley P. Fuhrman, Stephen F. Flaim, Lynn J. Hernan, Frances D. Nesti, Michele C. Papo, David M. Steinhorn