Abstract: Methods and apparatus for determining which displayed content, e.g., text, of a PDF document is selected and then taking an action based on the text selection, e.g., highlighting, coping, or editing the selected text. The methods and apparatus take into consideration potentially differences between text position and/or size differences between rendered and displayed page content and text position and/or size information obtained from performing a text extraction operation on the content of a PDF document. By combining extracted text information with post-render information corresponding to individual DOM elements in synthesized text elements and then storing the information in an easily access data structure, accurate identification of selected text characters can be made in a relatively fast manner using a browser implemented application.

Abstract: The present invention provides a method for detecting the presence or risk of bladder cancer in a female patient comprising the steps of detecting the presence of a panel of biomarkers in a sample isolated from a female patient, said panel of biomarkers comprising IL-13 and IL-12p70 and one or more biomarkers selected from BTA, Midkine, PAI-1/tPA, 8OHdG, CEA, CK18, Clusterin, Creatinine, CXCL16, Cystatin B, Cystatin C, d-Dimer, EGF, FAS, HAD, IL-1a, IL-1b, IL-4, IL-6, IL-7, IL-8, MCP-1, Microalbumin, MMP9NGAL, MMP9TIMP1, NGAL, NSE, Progranulin, TUP, TGFB1, Thrombomodulin, sTNFR1, TPA, VEGF and Triglycerides and/or the concentration of albumin/microalbumin/protein and creatinine expressed as an albumin:creatinine ratio in a sample isolated from a female patient; and assessing the results and comparing them to a normal control wherein an elevated presence of the biomarker compared to a normal control indicates the presence or risk of cancer in the patient from whom the sample is isolated.

Abstract: The present invention provides a method and a solid state device for identifying the presence of urothelial cancer in a patient comprising assigning the subject to a sub-population according to smoking habits, measuring the level of each biomarker of a panel of biomarkers in one or more samples obtained from the subject; and correlating the measured levels of the panel of biomarkers with the likelihood of the subject having urothelial cancer such that the subject can be classified as having urothelial cancer or as being a control.

Abstract: A butt-end device or knob for a sports implement with a handle for holding the sports implement. The butt-end device or knob has an inner member or inner surface mountable adjacent to a longitudinal end of the handle and a hand-engaging surface to engage a user's hand when holding the handle, the hand-engaging surface being movable relative to the handle in order to follow movement of the user's hand when the user swings the sports implement.

Abstract: The present invention provides a method and a solid state device for identifying the presence of urothelial cancer in a patient comprising assigning the subject to a sub-population according to smoking habits, measuring the level of each biomarker of a panel of biomarkers in one or more samples obtained from the subject; and correlating the measured levels of the panel of biomarkers with the likelihood of the subject having urothelial cancer such that the subject can be classified as having urothelial cancer or as being a control.

Abstract: A composite ball bat or other sporting-good implement includes a handle and a barrel attached to or integral with the handle. The barrel has a wall including a first structural region and a second structural region between which a porous separation layer is positioned. The separation layer is at least partially coated with a release agent that prevents, or substantially prevents, adherence of the separation layer to at least one of the first or second structural regions.

Abstract: A butt-end device or knob for a sports implement with a handle for holding the sports implement. The butt-end device or knob has an inner member or inner surface mountable adjacent to a longitudinal end of the handle and a hand-engaging surface to engage a user's hand when holding the handle, the hand-engaging surface being movable relative to the handle in order to follow movement of the user's hand when the user swings the sports implement.

Abstract: A butt-end device or knob for a sports implement with a handle for holding the sports implement. The butt-end device or knob has an inner member or inner surface mountable adjacent to a longitudinal end of the handle and a hand-engaging surface to engage a user's hand when holding the handle, the hand-engaging surface being movable relative to the handle in order to follow movement of the user's hand when the user swings the sports implement.

Abstract: A butt-end device or knob for a sports implement with a handle for holding the sports implement. The butt-end device or knob has an inner member or inner surface mountable adjacent to a longitudinal end of the handle and a hand-engaging surface to engage a user's hand when holding the handle, the hand-engaging surface being movable relative to the handle in order to follow movement of the user's hand when the user swings the sports implement.

Abstract: An immunoassay for the detection of tilidine and nortilidine is described. The invention also describes antibodies and kits.

Abstract: The invention relates to the detection and quantification of carbamazepine drugs and their metabolites. The invention is underpinned by novel polyclonal antibodies with unique binding properties which enable immunoassay methods and kits for various applications.

Abstract: The invention relates to a novel antibody which binds to wild type (wt) Glutathione S-transferase Omega 1 (wtGSTO1) but not to mutant (mut) GSTO1 and methods and uses based on the antibody. The antibody is based on novel haptens and immunogens.

Abstract: The invention relates to the detection and quantification of carbamazepine drugs and their metabolites. The invention is underpinned by novel polyclonal antibodies with unique binding properties which enable immunoassay methods and kits for various applications.

Abstract: The invention relates to a novel antibody which binds to wild type (wt) Glutathione S-transferase Omega 1 (wtGSTO1) but not to mutant (mut) GSTO1 and methods and uses based on the antibody. The antibody is based on novel haptens and immunogens.

Abstract: The disclosed methods, systems, and computer-program products allow a business to estimate linking errors in customer relationships in a database and to identify metrics that improve the linking accuracy. In an embodiment, a plurality of sample customer relationships are selected from a database to form a sample data set that is statistically representative of the database. Potential linking errors are then identified within the sample data set. The identified potential linking errors are then validated to identify actual linking errors in the sample data set. Once validated, the actual linking errors within the sample data set are used to estimate linking errors within the database. Further, the estimated linking errors in the database may be analyzed to identify one or more factors that contribute to the linking errors.

Abstract: This invention relates to a novel protein, termed INSP201, herein identified as a cell surface glycoprotein, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.

Abstract: A multi-walled, tubular baseball bat has a barrel portion with a mid-section wherein the radial stiffness of the overall barrel wall varies along the barrel length to provide an enlarged sweetspot, improved soft feel and performance, plus unique sounds upon impact. The bat has a frame with a barrel portion of consistent diameter. A secondary member, or members, of tubular form extend internally along the barrel. The secondary member provides the required radial stiffness variation by: 1) variations in the thickness of the wall of the secondary member or by, 2) secondary members with unique geometric external surface profiles or by, 3) the presence of functional air cavities, with or without closed ends, between the main bat frame and the secondary member or members or by, 4) the presence of numerous annular secondary members located side by side less than one-half the length of the barrel portion.

Abstract: The disclosed methods, systems, and computer-program products allow a business to estimate linking errors in customer relationships in a database and to identify metrics that improve the linking accuracy. In an embodiment, a plurality of sample customer relationships are selected from a database to form a sample data set that is statistically representative of the database. Potential linking errors are then identified within the sample data set. The identified potential linking errors are then validated to identify actual linking errors in the sample data set. Once validated, the actual linking errors within the sample data set are used to estimate linking errors within the database. Further, the estimated linking errors in the database may be analyzed to identify one or more factors that contribute to the linking errors.