Abstract: A method for treating onychomycosis and skin conditions such as urushiol-induced allergic contact dermatitis comprises coating the affected nail or skin with a solution comprising an at least a primary diamine with modified diphenylmethane diisocyanates and a carrier solvent/reactant.

Abstract: A method for treating onychomycosis and skin conditions such as urushiol-induced allergic contact dermatitis comprises coating the affected nail or skin with a solution comprising an at least a primary diamine with modified diphenylmethane diisocyanates and a carrier solvent/reactant.

Abstract: A system and method for wood preservation comprises treating wood products via conventional pressure treating mechanics of sequential vacuum and pressure with a solution comprising an oligomeric, stoichiometrically balanced blend of primary and secondary diamines with modified diphenylmethane diisocyanates and a carrier solvent/reactant. Upon application, the carrier solvent/reactant evaporates, allowing polymerization of the remaining solution constituents to form a non-toxic, hydrophobic, elastomeric polyureathane linked copolymer that provides a long-term barrier against rot, environmental, termite and mold/fungus attack. Complete polymer impregnation of the wood's interstitial fiber space enables the hydrophobic property of the polymer to provide a long-time barrier to water penetration. Alternatively, the polymer may be surface applied to provide both protection and to prevent leaching out of CCA chemicals in the case of conventionally treated wood. The polymer is also an effective termiticide.

Abstract: A system and method for wood preservation comprises treating wood products via conventional pressure treating mechanics of sequential vacuum and pressure with a solution comprising an oligomeric, stoichiometrically balanced blend of primary and secondary diamines with modified diphenylmethane diisocyanates and a carrier solvent/reactant. Upon application, the carrier solvent/reactant evaporates, allowing polymerization of the remaining solution constituents to form a non-toxic, hydrophobic, elastomeric polyureathane linked copolymer that provides a long-term barrier against rot, environmental, termite and mold/fungus attack. Complete polymer impregnation of the wood's interstitial fiber space enables the hydrophobic property of the polymer to provide a long-time barrier to water penetration. Alternatively, the polymer may be surface applied to provide both protection and to prevent leaching out of CCA chemicals in the case of conventionally treated wood. The polymer is also an effective termiticide.

Abstract: A bi-ventricular cardiac assist device maintains blood circulation in a patient having a minimally functioning or malfunctioning heart. The biventricular cardiac assist device includes a self-supporting cup-shaped outer shell having opposed upper and lower ends, and an inner surface which establishes an interior cavity for receiving a heart therein. The outer shell defines a pair of diametrically opposed slots oriented generally longitudinally between the upper and lower ends of the outer shell. An annular diaphragm conformably shaped to the outer shell is positioned adjacent to the outer shell's inner surface. The diaphragm most preferably includes upper and lower edges bonded to the outer shell at the upper and lower ends thereof, and a pair of diametrically opposed, generally longitudinally oriented unitary connection flange. Each connection flange is preferably generally T-shaped in cross-section and coupled to a respective one of the slots.

Abstract: A direct mechanical bi-ventricular cardiac assist device comprises a ventricular actuation cup having two independently operated diaphragms for independently actuating the right and left ventricle of the patient's heart. The pressure and timing of each diaphragm can be independently varied to maximize forward cardiac output. The ventricular actuation cup is constructed in two components including a main body section and an end piece. The diaphragm wraps around the ends of the main body section and the edges of the diaphragm are bonded to the outer surface of the main body section. Bonding of the diaphragm to the outer surface of the ventricular actuation cup eliminates lifting and tearing vectors which could result in diaphragm failure.

Abstract: A bi-ventricular cardiac assist device maintains blood circulation in a patient having a minimally functioning or malfunctioning heart. The biventricular cardiac assist device includes a self-supporting cup-shaped outer shell having opposed upper and lower ends, and an inner surface which establishes an interior cavity for receiving a heart therein. The outer shell defines a pair of diametrically opposed slots oriented generally longitudinally between the upper and lower ends of the outer shell. An annular diaphragm conformably shaped to the outer shell is positioned adjacent to the outer shell's inner surface. The diaphragm most preferably includes upper and lower edges bonded to the outer shell at the upper and lower ends thereof, and a pair of diametrically opposed, generally longitudinally oriented unitary connection flange. Each connection flange is preferably generally T-shaped in cross-section and coupled to a respective one of the slots.

Abstract: A method for fabricating human tissue prosthesis. The method produces a prosthesis that has mechanical compliance properties similar to that of body tissue. The prosthesis fabrication method utilizes, for example, a polyurethane urea-linked block copolymer system which in the cured state is a thermoset elastomer which has lumen surface qualities which are essentially optically flat. The formulation is essentially a single a single step process. A clean mandrel is horizontally clasped in the jaws of a variable speed motor and slowly rotated. The pre-polymer solution is placed on the rotating mandrel and thickness adjusted by a mechanical wiper. The rotating mandrel having pre-polymer of desired thickness is placed in a sub-atmospheric environment to remove dissolved gasses and permitted to initially cure while rotating. The final cure is achieved in a sub-atmospheric environment.