Patents by Inventor Stephen Gregory DiMagno

Stephen Gregory DiMagno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorination of aromatic ring systems
    Patent number: 9302990
    Abstract: This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18F labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: April 5, 2016
    Assignee: NUtech Ventures
    Inventor: Stephen Gregory DiMagno
  • Fluorination of Aromatic Ring Systems
    Publication number: 20110313170
    Abstract: This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18F labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.
    Type: Application
    Filed: June 30, 2011
    Publication date: December 22, 2011
    Inventor: Stephen Gregory DiMagno
  • Methods and agents for preparing F-radiolabeled fluorinating agents
    Patent number: 7744851
    Abstract: The present invention is directed to a method for preparing an anhydrous 18F-radiolabeled fluorinating agent by a nucleophilic reaction of a hydrated 18F-radiolabeled fluoride ion source with an unsaturated carrier compound; treating the 18F-radiolabeled carrier compound to produce a non-aqueous mixture of the 18F-radiolabeled carrier compound in a solvent; and reacting the 18F-radiolabeled carrier compound with a nucleophilic composition in a nucleophilic reaction to produce an anhydrous 18F-radiolabeled fluorinating agent. The present invention is also directed to an anhydrous 18F-radiolabeled fluorinating agent comprising the formula [QnM]x+(18F?)x. Additionally, the present invention is directed to an 18F-radiolabeled fluorinated radiopharmaceutical or an 18F-radiolabeled fluorinated radiotracer prepared by reacting the anhydrous 18F-radiolabeled fluorinating agent with a drug intermediate.
    Type: Grant
    Filed: July 16, 2007
    Date of Patent: June 29, 2010
    Assignee: Board Of Regents Of The University Of Nebraska
    Inventors: Stephen Gregory DiMagno, Haoran Sun