Patents by Inventor Stephen J. MacDonald

Stephen J. MacDonald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8371296
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: February 12, 2013
    Assignee: Geno, LLC
    Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • Patent number: 8221800
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: July 17, 2012
    Assignee: Geno LLC
    Inventors: David H. Fine, Stephen J. MacDonald, David R. Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • Patent number: 8066904
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: November 29, 2011
    Assignee: Geno LLC
    Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • Patent number: 7040313
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: May 9, 2006
    Assignee: CyTerra Corporation
    Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • Patent number: 7025869
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: April 11, 2006
    Assignee: CyTerra Corporation
    Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • Publication number: 20030064115
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Application
    Filed: August 28, 2002
    Publication date: April 3, 2003
    Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • Publication number: 20030064028
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Application
    Filed: August 28, 2002
    Publication date: April 3, 2003
    Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • Publication number: 20030062043
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Application
    Filed: August 28, 2002
    Publication date: April 3, 2003
    Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • Patent number: 6485543
    Abstract: A gas chromatography system with suspended tubular separation column(s) in an enclosed convection oven where a gas medium is heated by at least two electrically powered heaters. A kit to modify gas chromatographic ovens for operation with at least two electrically powered heaters. The heaters are positioned to promote even heating along the length of the column(s) and shielding of the column(s) from radiant heat. The heaters can provide faster heating rates at elevated temperatures.
    Type: Grant
    Filed: September 16, 2000
    Date of Patent: November 26, 2002
    Inventors: Stephen J. MacDonald, Peter Germano, Edwin Jahngen
  • Patent number: 6237149
    Abstract: A lower leg protection means for preventing injury to a person's lower leg. The lower leg protection means includes a pair of thin, laterally curved rigid members which are enclosed with foam material such as polyfoam and which are essentially made of carbon fiber graphite. Each of the thin, laterally curved rigid members is fastened about a particular region of a person's lower leg with fasteners which includes a three first strips of hook and loop fasteners, a pair of elongate elastic members, and a pair of second strips of hook and loop fasteners attached to the elongate elastic members. One of the thin, laterally curved, padded rigid members is adapted to fit about and protect a person's shin, and the other of the thin, laterally curved, padded rigid members is adapted to fit about and protect a person's Achilles tendon.
    Type: Grant
    Filed: October 28, 1999
    Date of Patent: May 29, 2001
    Inventor: Stephen J. MacDonald
  • Patent number: 6013228
    Abstract: Disclosed is a method and apparatus for sampling and determining the presence of certain substances, such as residues of contaminants in containers. The method includes steps of: injecting compressed air into said containers in order to displace at least a portion of the contents thereof; evacuating a sample of the container contents so displaced by applying suction thereto; and analyzing the sample evacuated to determine the presence or absence of the certain residues therein. The compressed air is injected through a nozzle into an opening in the containers to displace a portion of the container contents and form a sample cloud outside of the container. The sample cloud is then at least partially evacuated by suction and the sample is analyzed for the presence of contaminants such as nitrogen containing compounds or hydrocarbons. The sample cloud may be split into first and second portions.
    Type: Grant
    Filed: April 22, 1993
    Date of Patent: January 11, 2000
    Assignee: The Coca-Cola Company
    Inventors: Eugene K. Achter, Dirk Appel, David H. Fine, Freeman W. Fraim, Stephen J. MacDonald
  • Patent number: 5808178
    Abstract: A high speed gas chromatography system includes a heated isothermal region and a gas chromatography column located externally to the isothermal region. The system also includes a detector and a flow path between the column and the detector. At least a portion of the flow path is positioned in the isothermal region.
    Type: Grant
    Filed: October 16, 1996
    Date of Patent: September 15, 1998
    Assignee: Thermedics Detection Inc.
    Inventors: David P. Rounbehler, Eugene K. Achter, David H. Fine, George B. Jarvis, Stephen J. MacDonald, David B. Wheeler, Clayton D. Wood
  • Patent number: 5733783
    Abstract: An inspection system for sampling and determining the presence of residues of contaminants within plastic materials to be recycled from used plastic materials such as plastic beverage bottles or plastic food containers includes a chemical sniffing apparatus, or alternatively an optical scanner, for detecting the contaminants as the plastic materials are rapidly moved along a conveyor past a series of stations. Recycled food or beverage bottles are fed through a shredder in-line with the conveyor and the shredded plastic material from the bottles is fed to a washer. The bottles and shredded material may be tested for contaminants at any location in an in-line process. In one exemplary system first the bottles are tested prior to entry into the shredder in order to remove bottles containing gross contaminants.
    Type: Grant
    Filed: April 29, 1996
    Date of Patent: March 31, 1998
    Assignee: The Coca-Cola Company
    Inventors: David H. Fine, Freeman W. Fraim, Stephen J. MacDonald, Alex Malaspina, Forrest Lee Bayer, Dirck vanBuren Myers
  • Patent number: 5688693
    Abstract: An inspection system for sampling and determining the presence of residues of contaminants within plastic materials to be recycled from used plastic materials such as plastic beverage bottles or plastic food containers includes a chemical sniffing apparatus, or alternatively an optical scanner, for detecting the contaminants as the plastic materials are rapidly moved along a conveyor past a series of stations. Recycled food or beverage bottles are fed through a shredder in-line with the conveyor and the shredded plastic material from the bottles is fed to a washer. The bottles and shredded material may be tested for contaminants at any location in an in-line process. In one exemplary system first the bottles are tested prior to entry into the shredder in order to remove bottles containing gross contaminants.
    Type: Grant
    Filed: April 29, 1996
    Date of Patent: November 18, 1997
    Assignee: The Coca-Cola Company
    Inventors: David H. Fine, Freeman W. Fraim, Stephen J. MacDonald, Alex Malaspina, Forrest Lee Bayer, Dirck vanBuren Myers
  • Patent number: 5569606
    Abstract: An inspection system for sampling and determining the presence of residues of contaminants within plastic materials to be recycled from used plastic materials such as plastic beverage bottles or plastic food containers includes a chemical sniffing apparatus, or alternatively an optical scanner, for detecting the contaminants as the plastic materials are rapidly moved along a conveyor past a series of stations. Recycled food or beverage bottles are fed through a shredder in-line with the conveyor and the shredded plastic material from the bottles is fed to a washer. The bottles and shredded material may be tested for contaminants at any location in an in-line process. In one exemplary system first the bottles are tested prior to entry into the shredder in order to remove bottles containing gross contaminants.
    Type: Grant
    Filed: May 31, 1994
    Date of Patent: October 29, 1996
    Assignee: The Coca-Cola Company
    Inventors: David H. Fine, Freeman W. Fraim, Stephen J. MacDonald, Alex Malaspina, Forrest L. Bayer, Dirck van Buren Myers
  • Patent number: 5567623
    Abstract: A system and method are provided for minimizing the effects of background signals in masking signals indicating the presence of substances to be detected such as contaminants in materials moving rapidly along a conveyor. The contaminants detected may include nitrogen containing compounds and hydrocarbons. The system and method of the present invention minimizes the number of falsely positive indications of the presence of such substances due to background signals and changes in background signals. The substances detected are divided into first and second sample portions and the respective portions are heated. The first heated portion is reacted with ozone to generate radiation by chemiluminescence having characteristic wavelengths related to substances in the first portion. The second portion heated is also reacted with ozone to generate radiation by chemiluminescence having characteristic wavelengths related to substances in the second portion.
    Type: Grant
    Filed: April 4, 1995
    Date of Patent: October 22, 1996
    Assignee: The Coca-Cola Company
    Inventors: David P. Rounbehler, David H. Fine, Eugene K. Achter, Stephen J. MacDonald, Daniel B. Dennison
  • Patent number: 5561068
    Abstract: A system and method for minimizing the effects of background signals in masking signals indicating the presence of substances to be detected such as contaminants in materials moving rapidly along a conveyor. The contaminants detected may include nitrogen containing compounds and hydrocarbons. The system and method minimize, during detection of the presence or absence of such substances, the number of falsely positive indications of the presence of such substances due to background signals and changes in background signals. The substances detected are divided into first and second sample portions and the respective portions are heated. The first heated portion is mixed with ozone to cause a chemical action therewith in order to generate radiation by chemiluminescence having characteristic wavelengths related to substances in the first portion.
    Type: Grant
    Filed: April 4, 1995
    Date of Patent: October 1, 1996
    Assignee: The Coca-Cola Company
    Inventors: David P. Rounbehler, David H. Fine, Eugene K. Achter, Stephen J. MacDonald, Daniel B. Dennison
  • Patent number: 5493890
    Abstract: A method and apparatus for calibrating contraband vapor/particle detection devices is described. The invention includes a desorb site onto which may be deposited solutions containing known concentrations of one or more of the specific compounds to be detected. The desorb site, which may be rapidly heated to vaporize the particles contained in the solution deposited on its surface, is housed in a sealable chamber. The vapor and/or particles become entrained in an air stream forced across the surface of the desorb site, and the airstream is then delivered through a snout to the contraband vapor particle detector.
    Type: Grant
    Filed: March 16, 1994
    Date of Patent: February 27, 1996
    Assignee: Thermedics Detection Inc.
    Inventors: Daniel A. Dussault, William A. Curby, Stephen J. MacDonald, Edward E. A. Bromberg
  • Patent number: 5472882
    Abstract: Disclosed is an improved method and system for injecting liquid into containers and for inspecting containers for the presence of certain substances such as potential contaminants such as ammonium salts or amine salts in glass or plastic bottles. A high speed system and method are provided for detecting these contaminants in these bottles. Ammonia and amines can be detected by chemiluminescence of samples of volatiles emitted from the bottles during the high speed inspection process. A solution of Na.sub.2 CO.sub.3 is injected into the bottles in order to enhance the conversion of ammonium or amine salts to free ammonia or amines which are then released as vapors. This enhances the likelihood that a gas-phase detection system such as one using chemiluminescence detection techniques will detect the presence of contaminants containing ammonium salts or amine salts.
    Type: Grant
    Filed: October 3, 1994
    Date of Patent: December 5, 1995
    Assignee: The Coca-Cola Company
    Inventors: David P. Rounbehler, Eugene K. Achter, David H. Fine, Freeman W. Fraim, Stephen J. MacDonald, Helmut W. Klotzsch
  • Patent number: 5470754
    Abstract: A system and method are provided for minimizing the effects of background signals in masking signals indicating the presence of substances to be detected such as contaminants in materials moving rapidly along a conveyor. The contaminants detected may include nitrogen containing compounds and hydrocarbons. The system and method of the present invention minimize during detection of the presence or absence of such substances, the number of falsely positive indications of the presence of such substances due to background signals and changes in background signals. The substances detected are divided into first and second sample portions and the respective portions are heated. The first heated portion is mixed with ozone to cause a chemical reaction therewith in order to generate radiation by chemiluminescence having characteristic wavelengths related to substances in the first portion.
    Type: Grant
    Filed: February 22, 1993
    Date of Patent: November 28, 1995
    Assignee: The Coca-Cola Company
    Inventors: David P. Rounbehler, David H. Fine, Eugene K. Achter, Stephen J. MacDonald, Daniel B. Dennison