Abstract: Disclosed herein include antibodies or fragments thereof having specificity to a sarbecovirus spike protein. Also provided are compositions, methods, and kits for using said antibodies or fragments thereof for preventing or treating, for example a coronavirus infection.

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: A network element of a transport network has three fabrics housed within a single shelf of a telco rack, namely a packet fabric, an electrical fabric and an optical fabric. A stream of traffic including a plurality of lambdas is received at a trunk interface of such a shelf. The optical fabric in the shelf performs optical switching on the stream to replace a first lambda in the stream with a second lambda. The first lambda is converted within the shelf into an electrical signal. Also within the shelf, first frames are recovered from the electrical signal. The packet fabric in the shelf is used to perform packet switching on the first frames to generate a flow of second frames. The flow of second frames is transmitted at a client interface of the shelf.

Abstract: A communications network is provided for a water treatment system. A controller is in communication with a plurality of network elements using digital communications. The network elements have a connection configured to connect the network element to the controller or another network element. The controller sends a message to the network elements to configure the network elements for communication with the controller. The controller receives a response from the network elements including a network address and a header. If the network address is a default address, configuration information is sent to the network element for communication on the network. If the network address is not a default address, communication is established with the network element. Messages sent from the controller to a network element having a network address not matching the network address of the network element are sent over the network to a next network element.

Abstract: A network element of a transport network has three fabrics housed within a single shelf of a telco rack, namely a packet fabric, an electrical fabric and an optical fabric. A stream of traffic including a plurality of lambdas is received at a trunk interface of such a shelf. The optical fabric in the shelf performs optical switching on the stream to replace a first lambda in the stream with a second lambda. The first lambda is converted within the shelf into an electrical signal. Also within the shelf, first frames are recovered from the electrical signal. The packet fabric in the shelf is used to perform packet switching on the first frames to generate a flow of second frames. The flow of second frames is transmitted at a client interface of the shelf.

Abstract: A network element of a transport network has three fabrics housed within a single shelf of a telco rack, namely a packet fabric, an electrical fabric and an optical fabric. A stream of traffic including a plurality of lambdas is received at a trunk interface of such a shelf. The optical fabric in the shelf performs optical switching on the stream to replace a first lambda in the stream with a second lambda. The first lambda is converted within the shelf into an electrical signal. Also within the shelf, first frames are recovered from the electrical signal. The packet fabric in the shelf is used to perform packet switching on the first frames to generate a flow of second frames. The flow of second frames is transmitted at a client interface of the shelf.

Abstract: Heat dissipating electronic components and circuitry in a communication chassis are cooled by moving air at least through a midplane, between two groups of channels that are perpendicularly oriented relative to one another. In an illustrative embodiment, channels of one group are oriented vertically while channels of another group are oriented horizontally. Each channel, regardless of whether it is vertical or horizontal, is defined by space in the chassis between adjacent circuit boards. Circuit boards on one side of the midplane are electrically connected to circuit boards on the other side of the midplane by orthogonal connectors on the midplane. The midplane additionally has openings that enable movement of air between vertically-oriented channels and horizontally-oriented channels. Circuit boards of the two orientations are cooled by increasing air pressure in vertically-oriented channels or by decreasing air pressure in horizontally-oriented channels or both, depending on the embodiment.

Abstract: A network element of a transport network has three fabrics housed within a single shelf of a telco rack, namely a packet fabric, an electrical fabric and an optical fabric. A stream of traffic including a plurality of lambdas is received at a trunk interface of such a shelf. The optical fabric in the shelf performs optical switching on the stream to replace a first lambda in the stream with a second lambda. The first lambda is converted within the shelf into an electrical signal. Also within the shelf, first frames are recovered from the electrical signal. The packet fabric in the shelf is used to perform packet switching on the first frames to generate a flow of second frames. The flow of second frames is transmitted at a client interface of the shelf.

Abstract: A network element of a transport network has three fabrics housed within a single shelf of a telco rack, namely a packet fabric, an electrical fabric and an optical fabric. A stream of traffic including a plurality of lambdas is received at a trunk interface of such a shelf. The optical fabric in the shelf performs optical switching on the stream to replace a first lambda in the stream with a second lambda. The first lambda is converted within the shelf into an electrical signal. Also within the shelf, first frames are recovered from the electrical signal. The packet fabric in the shelf is used to perform packet switching on the first frames to generate a flow of second frames. The flow of second frames is transmitted at a client interface of the shelf.

Abstract: A communications network is provided for a water treatment system. A controller is in communication with a plurality of network elements using digital communications. The network elements have a connection configured to connect the network element to the controller or another network element. The controller sends a message to the network elements to configure the network elements for communication with the controller. The controller receives a response from the network elements including a network address and a header. If the network address is a default address, configuration information is sent to the network element for communication on the network. If the network address is not a default address, communication is established with the network element. Messages sent from the controller to a network element having a network address not matching the network address of the network element are sent over the network to a next network element.

Abstract: A communications network is provided for a water treatment system. A controller is in communication with a plurality of network elements using digital communications. The network elements have a connection configured to connect the network element to the controller or another network element. The controller sends a message to the network elements to configure the network elements for communication with the controller. The controller receives a response from the network elements including a network address and a header. If the network address is a default address, configuration information is sent to the network element for communication on the network. If the network address is not a default address, communication is established with the network element. Messages sent from the controller to a network element having a network address not matching the network address of the network element are sent over the network to a next network element.

Abstract: A water treatment sensor includes a housing having a bottom with an exterior surface in contact with a flow path of a fluid and an interior surface. First and second probes spaced from one another extend from the exterior surface and into the flow path. A first circuit electrically connects the first and second probes and determines a conductivity from a measured resistivity between the probes. First and second temperature sensors are spaced from one another and are coupled to the interior surface. The first sensor determines a temperature of the fluid. A temperature elevated by a heat source and determined by the second sensor is maintained above the temperature of the fluid. A second circuit determines a flow rate of the fluid based on adjustments to the heat source. Communication circuitry communicates the conductivity, the temperature, and the flow rate of the fluid to a controller.

Abstract: Heat dissipating electronic components and circuitry in a communication chassis are cooled by moving air at least through a midplane, between two groups of channels that are laterally oriented relative to one another. In an illustrative embodiment, channels of one group are oriented vertically while channels of another group are oriented horizontally. Each channel, regardless of whether it is vertical or horizontal, is defined by space in the chassis between adjacent circuit boards. Circuit boards on one side of the midplane are electrically connected to circuit boards on the other side of the midplane by orthogonal connectors on the midplane. The midplane additionally has openings that enable movement of air between vertically-oriented channels and horizontally-oriented channels. Circuit boards of the two orientations are cooled by increasing air pressure in vertically-oriented channels or by decreasing air pressure in horizontally-oriented channels or both, depending on the embodiment.

Abstract: A network element of a transport network has three fabrics housed within a single shelf of a telco rack, namely a packet fabric, an electrical fabric and an optical fabric. A stream of traffic including a plurality of lambdas is received at a trunk interface of such a shelf. The optical fabric in the shelf performs optical switching on the stream to replace a first lambda in the stream with a second lambda. The first lambda is converted within the shelf into an electrical signal. Also within the shelf, first frames are recovered from the electrical signal. The packet fabric in the shelf is used to perform packet switching on the first frames to generate a flow of second frames. The flow of second frames is transmitted at a client interface of the shelf.

Abstract: A controller for water treatment in a cooling system includes a processor, a user interface, a plurality of relays, at least one network port, and at least one communication port. The processor is configured to monitor cooling fluid in the cooling system and cause the system to drain fluid when an amount of dissolved solid in the fluid exceeds a predetermined threshold. The plurality of relays are configured for both wet operation and dry operation. The controller is accessed using a web server on the controller through a communication port. The controller is controller and control parameters are modified via the web server. A relay of the plurality of relays in the controller is configured for either wet operation or dry operation. The configuration of the relay of the plurality of relays is dynamically changed to the other of wet operation or dry operation.

Abstract: A shelf of communication equipment provides frontal illumination of a face plate of the shelf. Specifically, a shelf in a rack in a communication network includes a face plate and a bezel. The face plate has a first exterior surface that carries a legend. The bezel forms a second exterior surface extending in a predetermined direction transverse to the first exterior surface. For example, if the first exterior surface is vertical, the second exterior surface is horizontal and overhangs the first exterior surface. During operation, electromagnetic radiation generated by a source enclosed by the bezel exits through the second exterior surface and directly illuminates at least the legend, and optionally also illuminates a electronic device adjacent to the legend, such as an LED or a jack, if such a device is present on the first exterior surface.

Abstract: A communications network is provided for a water treatment system. A controller is in communication with a plurality of network elements using digital communications. The network elements have a connection configured to connect the network element to the controller or another network element. The controller sends a message to the network elements to configure the network elements for communication with the controller. The controller receives a response from the network elements including a network address and a header. If the network address is a default address, configuration information is sent to the network element for communication on the network. If the network address is not a default address, communication is established with the network element. Messages sent from the controller to a network element having a network address not matching the network address of the network element are sent over the network to a next network element.

Abstract: A controller for water treatment in a cooling system includes a processor, a user interface, a plurality of relays, at least one network port, and at least one communication port. The processor is configured to monitor cooling fluid in the cooling system and cause the system to drain fluid when an amount of dissolved solid in the fluid exceeds a predetermined threshold. The plurality of relays are configured for both wet operation and dry operation. The controller is accessed using a web server on the controller through a communication port. The controller is controller and control parameters are modified via the web server. A relay of the plurality of relays in the controller is configured for either wet operation or dry operation. The configuration of the relay of the plurality of relays is dynamically changed to the other of wet operation or dry operation.

Abstract: A water treatment sensor includes a housing having a bottom with an exterior surface in contact with a flow path of a fluid and an interior surface. First and second probes spaced from one another extend from the exterior surface and into the flow path. A first circuit electrically connects the first and second probes and determines a conductivity from a measured resistivity between the probes. First and second temperature sensors are spaced from one another and are coupled to the interior surface. The first sensor determines a temperature of the fluid. A temperature elevated by a heat source and determined by the second sensor is maintained above the temperature of the fluid. A second circuit determines a flow rate of the fluid based on adjustments to the heat source. Communication circuitry communicates the conductivity, the temperature, and the flow rate of the fluid to a controller.

Abstract: A network element of a transport network has three fabrics housed within a single shelf of a telco rack, namely a packet fabric, an electrical fabric and an optical fabric. The shelf also includes inter-fabric circuitry, to bridge between the fabrics, e.g. packet-electrical and/or electrical-optical and/or packet-optical. The inter-fabric circuitries switchably transmit packets across fabrics in intermediate nodes of the transport network. The single shelf of some embodiments has a wall (“midplane”) between a rear region that holds the three fabrics and a front region that holds inter-fabric circuitry, and external interfaces to optical trunks and/or packet services and/or optical tributaries.