Patents by Inventor Stephen M. Beverley

Stephen M. Beverley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF ANTIVIRALS TO INHIBIT PROTOZOAN VIRUSES
    Publication number: 20190307783
    Abstract: The present disclosure relates to compositions comprising anti-viral therapeutics and methods of use thereof in killing parasites. Also described are methods of treating a parasitic infection; methods of screening a library for compounds effective in treating parasitic infections; and methods of diagnosing a parasitic infection.
    Type: Application
    Filed: December 7, 2017
    Publication date: October 10, 2019
    Inventors: Stephen M. Beverley, F. Matthew Kuhlmann
  • Targeted Therapeutic Proteins
    Publication number: 20190224282
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: April 9, 2019
    Publication date: July 25, 2019
    Inventors: Jonathan LeBowitz, Stephen M. Beverley
  • Targeted therapeutic proteins
    Patent number: 10300113
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: May 28, 2019
    Assignee: BioMarin Pharmaceutical Inc.
    Inventors: Jonathan LeBowitz, Stephen M. Beverley
  • Targeted Therapeutic Proteins
    Publication number: 20180055911
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: July 26, 2017
    Publication date: March 1, 2018
    Inventors: Jonathan LeBowitz, Stephen M. Beverley
  • Targeted therapeutic proteins
    Patent number: 9814762
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: November 14, 2017
    Assignee: BioMarin Pharmaceutical Inc.
    Inventors: Jonathan LeBowitz, Stephen M. Beverley
  • TARGETED THERAPEUTIC PROTEINS
    Publication number: 20160152680
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: February 5, 2016
    Publication date: June 2, 2016
    Inventors: Jonathan LeBowitz, Stephen M. Beverley
  • TARGETED THERAPEUTIC PROTEINS
    Publication number: 20150064183
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: September 11, 2014
    Publication date: March 5, 2015
    Inventors: Jonathan LeBowitz, Stephen M. Beverley
  • Targeted therapeutic proteins
    Patent number: 8859498
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: October 14, 2014
    Assignee: Biomarin Pharmaceutical Inc.
    Inventors: Jonathan LeBowitz, Stephen M. Beverley
  • TARGETED THERAPEUTIC PROTEINS
    Publication number: 20140056867
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: June 18, 2013
    Publication date: February 27, 2014
    Applicant: BIOMARIN PHARMACEUTICAL
    Inventors: Jonathan LeBowitz, Stephen M. Beverley
  • Targeted therapeutic proteins
    Patent number: 8492338
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: July 23, 2013
    Assignee: Biomarin Pharmaceutical Inc.
    Inventors: Jonathan LeBowitz, Stephen M. Beverley, William S. Sly
  • Targeted therapeutic proteins
    Patent number: 8492337
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Grant
    Filed: August 3, 2011
    Date of Patent: July 23, 2013
    Assignee: Biomarin Pharmaceutical Inc.
    Inventors: Jonathan LeBowitz, Stephen M. Beverley
  • Targeted Therapeutic Proteins
    Publication number: 20120295327
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: May 25, 2012
    Publication date: November 22, 2012
    Applicant: Biomarin Pharmaceutical Inc.
    Inventors: Jonathan H. LeBowitz, Stephen M. Beverley, William S. Sly
  • Targeted therapeutic proteins
    Patent number: 8207114
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: June 26, 2012
    Assignee: Biomarin Pharmaceutical Inc.
    Inventors: Jonathan H. LeBowitz, Stephen M. Beverley, William S. Sly
  • Targeted Therapeutic Proteins
    Publication number: 20120141452
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: August 3, 2011
    Publication date: June 7, 2012
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Jonathan H. LeBowitz, Stephen M. Beverley
  • Method for targeting lysosomal enzymes
    Patent number: 7858576
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: December 28, 2010
    Assignee: ZyStor Therapeutics, Inc.
    Inventors: Jonathan H. LeBowitz, Stephen M. Beverley
  • Targeted Therapeutic Proteins
    Publication number: 20100075906
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: November 2, 2009
    Publication date: March 25, 2010
    Applicant: Zystor Therapeutics, Inc.
    Inventors: Jonathan H. LeBowitz, Stephen M. Beverley, William S. Sly
  • Targeted therapeutic proteins
    Patent number: 7629309
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Grant
    Filed: November 3, 2004
    Date of Patent: December 8, 2009
    Assignee: Zystor Therapeutics, Inc.
    Inventors: Jonathan H. LeBowitz, Stephen M. Beverley, William S. Sly
  • TARGETED THERAPEUTIC PROTEINS
    Publication number: 20090203575
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: February 19, 2009
    Publication date: August 13, 2009
    Applicant: ZyStor Therapeutics, Inc.
    Inventors: Jonathan H. LeBowitz, Stephen M. Beverley
  • Targeted therapeutic proteins
    Patent number: 7560424
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: July 14, 2009
    Assignee: ZyStor Therapeutics, Inc.
    Inventors: Jonathan H. LeBowitz, Stephen M. Beverley
  • Method for targeting lysosomal enzymes
    Publication number: 20090029467
    Abstract: Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
    Type: Application
    Filed: May 30, 2007
    Publication date: January 29, 2009
    Applicant: ZyStor Therapeutics, Inc.
    Inventors: Jonathan H. LeBowitz, Stephen M. Beverley