Patents by Inventor Stephen N. Thibodeau

Stephen N. Thibodeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EARLY DETECTION OF PANCREATIC CANCER
    Publication number: 20130244902
    Abstract: This document provides methods and materials involved in the early detection of pancreatic cancer. For example, this document provides methods and materials for assessing nucleic acid obtained from a blood sample of a human for a CpG methylation site profile that, at least in part, indicates that the human has pancreatic cancer.
    Type: Application
    Filed: November 22, 2011
    Publication date: September 19, 2013
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Stephen N. Thibodeau, Liang Wang, Ann L. Oberg, Gloria M. Petersen, William R. Bamlet, Mariza de Andrade
  • Alterations in the copy number of the SULT1A1 gene
    Patent number: 7674583
    Abstract: Methods are described for determining sulfonator status of a patient and determining dosages of drugs based on copy number of the SULT1A1 gene.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: March 9, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Richard M. Weinshilboum, Araba A. Adjei, Scott J. Hebbring, Stephen N. Thibodeau
  • NOVEL GENES, COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF COLON CANCER
    Publication number: 20090029365
    Abstract: The invention relates to newly discovered nucleic acid molecules and proteins associated with colon cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human colon cancers are provided.
    Type: Application
    Filed: March 21, 2008
    Publication date: January 29, 2009
    Inventors: Allison Berger, Tracy L. Guillemette, Robert Schlegel, John E. Monahan, Shubhangi Kamatkar, Stephen N. Thibodeau, Lawrence J. Burgart
  • DETECTION METHODS USING TIMP1
    Publication number: 20080194043
    Abstract: The present invention relates to a method for detecting the presence of colorectal cancer in an individual, wherein colorectal cancer is detected by detecting the presence of Reg1? or TIMP1 nucleic acid or amino acid molecules in a clinical sample obtained from the patient, wherein Reg1? or TIMP1 expression is indicative of the presence of colorectal cancer. The invention further relates to a method for detecting the presence of colorectal cancer in an individual, wherein colorectal cancer is detected by detecting the presence of Reg1? or TIMP1 nucleic acid or amino acid molecules in a clinical sample, in addition to detecting the presence of one or more additional colorectal cancer associated markers.
    Type: Application
    Filed: March 21, 2008
    Publication date: August 14, 2008
    Inventors: Jon H. ASTLE, Christopher C. BURGESS, Theodore J. CATINO, Poornima DWIVEDI, Maryanne HUNTRESS, Karen Anne JOHNSON, Marcia E. LEWIS, Peter J. MAIMONIS, Gary A. MOLINO, Susan H. MYEROW, Arunthathi THIAGALINGAM, Lisa Allyn BOARDMAN, Lawrence J. BURGART, Stephen N. THIBODEAU, Sheryl BROWN-SHIMER
  • Detection methods using TIMP 1
    Publication number: 20040157278
    Abstract: The present invention relates to a method for detecting the presence of colorectal cancer in an individual, wherein colorectal cancer is detected by detecting the presence of Reg1&agr; or TIMP1 nucleic acid or amino acid molecules in a clinical sample obtained from the patient, wherein Reg1&agr; or TIMP1 expression is indicative of the presence of colorectal cancer. The invention further relates to a method for detecting the presence of colorectal cancer in an individual, wherein colorectal cancer is detected by detecting the presence of Reg1&agr; or TIMP1 nucleic acid or amino acid molecules in a clinical sample, in addition to detecting the presence of one or more additional colorectal cancer associated markers.
    Type: Application
    Filed: December 12, 2003
    Publication date: August 12, 2004
    Applicants: Bayer Corporation, Mayo Foundation for Medical Education & Research
    Inventors: Jon H. Astle, Christopher C. Burgess, Theodore J. Catino, Poornima Dwivedi, Maryanne Huntress, Karen Anne Johnson, Marcia E. Lewis, Peter J. Maimonis, Gary A. Molino, Susan H. Myerow, Arunthathi Thiagalingam, Lisa Allyn Boardman, Lawrence J. Burgart, Stephen N. Thibodeau, Sheryl Brown-Shimer
  • Novel human genes and gene expression products
    Publication number: 20040146879
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly in colon cancer tissue.
    Type: Application
    Filed: June 30, 2003
    Publication date: July 29, 2004
    Applicants: Bayer HealthCare LLC, Mayo Foundation for Medical Education & Research
    Inventors: Jon H. Astle, Lisa Allyn Boardman, Lawrence J. Burgart, Christopher C. Burgess, Theodore J. Catino, Poornima Dwivedi, Marcia E. Lewis, Gary A. Molino, Susan H. Myerow, Arunthathi Thiagalingam, Stephen N. Thibodeau
  • Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of colon cancer
    Publication number: 20030148410
    Abstract: The invention relates to newly discovered nucleic acid molecules and proteins associated with colon cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human colon cancers are provided.
    Type: Application
    Filed: November 21, 2002
    Publication date: August 7, 2003
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Allison Berger, Tracy L. Guillemette, Robert Schlegel, John E. Monahan, Shubhangi Kamatkar, Stephen N. Thibodeau, Lawrence J. Burgart