Patents by Inventor Stephen Roger Johnson

Stephen Roger Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR ESTIMATING hERG INHIBITION OF DRUG CANDIDATES USING MULTIVARIATE PROPERTY AND PHARMACOPHORE SAR
    Publication number: 20080227100
    Abstract: The present invention provides a computational model and methods of use thereof for predicting whether a compound is likely to inhibit K+ flow through the hERG ion channel. Methods for in silico screening of compounds that have a lower likelihood of inhibiting hERG are also provided.
    Type: Application
    Filed: March 12, 2008
    Publication date: September 18, 2008
    Inventor: Stephen Roger Johnson
  • Method for repairing partitions of a turbine diaphragm
    Patent number: 5895205
    Abstract: The repair method includes removing eroded or damaged trailing edge portions of partitions in the diaphragm of a turbine, over 50% of the length of the partitions being removed commencing at the trailing edge. A coupon which is a precise replication of a portion of an originally specified partition is welded to the remaining or extant partition portion by a seal weld along the radial length of the coupon on the suction side of the repaired partition and two full penetration welds at the ends of the coupon to secure it to the inner and outer rings or side walls of the diaphragm. The repaired partition is thus substantially identically contoured as the original partition.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: April 20, 1999
    Assignee: General Electric Co.
    Inventors: Dennis John Werner, Stephen Roger Johnson, Ralph A. Pollock
  • Method for repairing partitions of a turbine diaphragm
    Patent number: 5697151
    Abstract: The repair method includes removing eroded or damaged trailing edge portions of partitions in the diaphragm of a turbine, over 50% of the length of the partitions being removed commencing at the trailing edge. A coupon which is a precise replication of a portion of an originally specified partition is welded to the remaining or extant partition portion by a seal weld along the radial length of the coupon on the suction side of the repaired partition and two full penetration welds at the ends of the coupon to secure it to the inner and outer rings or side walls of the diaphragm. The repaired partition is thus substantially identically contoured as the original partition.
    Type: Grant
    Filed: August 7, 1995
    Date of Patent: December 16, 1997
    Assignee: General Electric Company
    Inventors: Dennis John Werner, Stephen Roger Johnson, Ralph A. Pollock