Patents by Inventor Stephen S. Szucs

Stephen S. Szucs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9249089
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: February 2, 2016
    Assignee: REATA PHARMACEUTICALS, INC.
    Inventors: Xin Jiang, Xiaofeng Liu, Jack Greiner, Stephen S. Szucs, Melean Visnick
  • Patent number: 8394967
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: March 12, 2013
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Xiaofeng Liu, Jack Greiner, Stephen S. Szucs, Melean Visnick
  • Patent number: 8338618
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: December 25, 2012
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • Publication number: 20120238767
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Application
    Filed: November 11, 2011
    Publication date: September 20, 2012
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • Patent number: 8071632
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: December 6, 2011
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • Publication number: 20110245206
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Application
    Filed: February 23, 2011
    Publication date: October 6, 2011
    Inventors: XIN JIANG, XIAOFENG LIU, JACK GREINER, STEPHEN S. SZUCS, MELEAN VISNICK
  • Patent number: 7943778
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: May 17, 2011
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Xiaofeng Liu, Jack Greiner, Stephen S. Szucs, Melean Visnick
  • Publication number: 20100048911
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Application
    Filed: April 20, 2009
    Publication date: February 25, 2010
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • Publication number: 20100041904
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Application
    Filed: April 20, 2009
    Publication date: February 18, 2010
    Inventors: Xin Jiang, Xiaofeng Liu, Jack Greiner, Stephen S. Szucs, Melean Visnick
  • Publication number: 20040260097
    Abstract: Compounds of formula (I), wherein the variables and the index have the following meanings: R1 H, halogen, alkyl, haloalkyl, alkenyl, haloalkenyl, alkylthio, alkoxyalkyl, alkylthioalkyl, or optionally substituted phenyl; R2 H, halogen, alkyl, haloalkyl, alkenyl, haloalkenyl or optionally substituted phenyl; A H, OH, CN, NO2, halogen, SCN, alkoxy, haloalkoxy, alkenyloxy, alkylthio, haloalkylthio, alkylsulfinyl, alkylsulfonyl, aminothiocarbonyl, hydroxycarbonyl, alkoxycarbonyl, or aminocarbonyl; B H, OH, NH2, CN, NO2, halogen, optionally substituted alkyl, optionally substituted alkoxy, optionally substituted alkenyl, alkenyloxy, alkylthio, haloalkylthio, alkoxythiocarbonylthio, alkoxycarbonylalkoxy, alkoxycarbonylalkylthio, alkylsulfinyl, alkylsulfonyl, aminothiocarbonyl, NR3R4, N═CHOR5, or N═CHNR5; R3, R4 H, alkyl, alkoxycarbonylalkyl, [(alkoxycarbonyl)(alkenyl)]alkyl, alkoxycarbonylalkenyl, alkylcarbonyl, cycloalkylcarbonyl, alkylaminocarbonyl, diaminocarbonyl, alkoxycarbonyl, alkoxyaminos
    Type: Application
    Filed: March 23, 2004
    Publication date: December 23, 2004
    Inventors: Joseph A. Furch, David Kuhn, Stephen S. Szucs, Kun-jian Gu, Wolfgang von Deyn
  • Patent number: 6465395
    Abstract: The present invention provides thiochroman- and dihydrobenzothiophene-substituted methylene compounds of formula I. Further provided are compositions and methods utilizing said formula I compounds for the control of undesirable plant species.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: October 15, 2002
    Assignees: BASF Aktiengesellschaft, Idemitsu Kosan Company, Ltd.
    Inventors: Stephen S. Szucs, Kun-Jian Gu
  • Patent number: 6413913
    Abstract: The present invention provides a compound of formula I: wherein X is O or S(O)n; n is zero, 1 or 2; and Y is CR7R8, CHOR9, C(OR9)2, C═NOR10 or C═NNR20R21. Compounds of formula I are useful as herbicidal agents, particularly as agents for the control of undesirable plant species in the presence of a cereal crop.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: July 2, 2002
    Assignees: BASF Corporation, Idemitsu Kosen Company, Ltd.
    Inventor: Stephen S. Szucs
  • Publication number: 20020058244
    Abstract: This invention relates to a method for identifying compounds that specifically inhibit a metabolic target site or pathway in plants. Enzymes which are specifically affected by the method of the invention include plant pyrimidine biosynthetic pathway enzymes, and particularly the enzymes involved in the conversion of orotate to uridine-5′-monophosphate (UMP). Further, the invention relates to a method for control of undesirable monocotyledenous and dicotyledenous plant species.
    Type: Application
    Filed: July 13, 2001
    Publication date: May 16, 2002
    Inventors: Marianne K. Pedersen, Iwona T. Birk, Ann B. Orth, Bijay K. Singh, Berhane Tecle, Venkataraman Kameswaran, Stephen S. Szucs
  • Publication number: 20020016261
    Abstract: The present invention provides thiochroman- and dihydrobenzothiophene-substituted methylene compounds of formula I.
    Type: Application
    Filed: February 28, 2001
    Publication date: February 7, 2002
    Inventors: Stephen S. Szucs, Kun-Jian Gu
  • Patent number: 4898609
    Abstract: The invention relates to selective herbicidal 4-cyano-4-(fluorophenyl)-3-(substituted-phenyl)butyric acids, esters and derivatives thereof, and a method of selectively controlling undesirable vegetation in rice therewith.
    Type: Grant
    Filed: October 9, 1987
    Date of Patent: February 6, 1990
    Assignee: American Cyanamid Company
    Inventors: Stephen S. Szucs, Laura S. Quakenbush, Pierre A. Marc
  • Patent number: 4313754
    Abstract: There are provided polysubstituted butanoic acids, esters and derivatives thereof, methods for preparing the same and herbicidal compositions employing said polysubstituted butanoic acids, esters and derivatives.
    Type: Grant
    Filed: January 28, 1980
    Date of Patent: February 2, 1982
    Assignee: American Cyanamid Company
    Inventor: Stephen S. Szucs
  • Patent number: 4224052
    Abstract: There are provided polysubstituted butanoic acids, esters and derivatives thereof, methods for preparing the same and herbicidal compositions employing said polysubstituted butanoic acids, esters and derivatives.
    Type: Grant
    Filed: May 5, 1978
    Date of Patent: September 23, 1980
    Assignee: American Cyanamid Company
    Inventor: Stephen S. Szucs