Abstract: The present invention provides an isolated animal cell comprising an exogenous nucleic acid encoding a mutated phytase, wherein the cell produces phytase and secretes the phytase from the cell. The present invention also provides an animal having a phenotype not naturally occurring, characterized by secretion of phytase into the lumen of the gastrointestinal tract of the animal, the phenotype being conferred by a transgene contained in the cells of the animal, the transgene comprising a nucleic acid sequence encoding phytase and methods of making said animal.

Abstract: Provided is a method of increasing 3,4,5,6-tetrakisphosphate by increasing the activity of inositol 1,3,4,5,6 pentakisphosphate 1-phosphatase, and a method of decreasing 3,4,5,6-tetrakisphosphate by decreasing the activity of inositol 1,3,4,5,6 pentakisphosphate 1-phosphatase. A method of reducing salt, fluid or mucous secretion in a subject, comprising increasing the activity of inositol 1,3,4,5,6 pentakisphosphate 1-phosphatase in the subject is provided. A method of treating a disease that is exacerbated by salt, fluid or mucous secretion is also provided, comprising increasing the activity of inositol 1,3,4,5,6 pentakisphosphate phosphatase in a subject having a disease that is exacerbated by mucous, whereby mucous secretion is reduced and the disease is treated. Also provided is method of increasing salt and fluid secretion in a subject, comprising decreasing the activity of inositol 1,3,4,5,6 pentakisphosphate 1-phosphatase in the subject.

Abstract: A drive device includes a first member including a first shoulder, and a second member positioned in close proximity to the first member and including a second shoulder. The device also includes a coupling arrangement including a strut having a first edge for direct engagement with the first shoulder, a second edge for engagement with the second shoulder and supported for pivotal movement between engaged and overrun positions, based on relative rotation of the first and second members such that the first member drives the second member in a drive mode with the strut in the engaged position and the first and second members can overrun with respect to one another with the strut in the overrun position. The coupling arrangement also includes a cushioning member disposed between the second edge and the second shoulder for cushioning each initial engagement of the strut in the drive mode.

Abstract: The present invention provides an isolated animal cell comprising an exogenous nucleic acid encoding a mutated phytase, wherein the cell produces phytase and secretes the phytase from the cell. The present invention also provides an animal having a phenotype not naturally occurring, characterized by secretion of phytase into the lumen of the gastrointestinal tract of the animal, the phenotype being conferred by a transgene contained in the cells of the animal, the transgene comprising a nucleic acid sequence encoding phytase and methods of making said animal.

Abstract: Improved electroerosion recording media are described in which ablatable polymers are used in the electroerosion recording medium. This medium includes at least a substrate or support layer, a base layer which protects the substrate, a thin film of conductive material on the base layer and which can be eroded, and a protective overcoat layer. Ablatable polymers are used as binders in either the base layer or the top protective layer, or both, in order to provide advantages during electroerosion. These ablatable polymers undergo thermally induced depolymerization in such a way that the result is the formation of volatile monomeric or low molecular weight species as the predominant products, with little or no adherent residue.