Abstract: An apparatus includes a sample receiving port and an inlet assembly configured to be positioned adjacent to the sample receiving port. The inlet assembly defines a volume for receiving a sample and includes a gap that defines an extraction port. The extraction port is configured to extract one fluid flow to facilitate another fluid flow toward the sample receiving port. The extraction port can be configured as an annular flow port around the sample receiving port. In some instances, the apparatus also includes a curtain port positioned apart from the sample receiving port and the extraction port. The curtain port can be used to guide fluid away from interior surfaces of the inlet assembly and toward the sample receiving port, and/or to provide an environment of controlled air, and/or to isolate the sample receiving port from external sources of contamination.

Abstract: An insulated electrical conductor (MI cable) may include an inner electrical conductor, an electrical insulator at least partially surrounding the electrical conductor, and an outer electrical conductor at least partially surrounding the electrical insulator. The insulated electrical conductor may have a substantially continuous length of at least about 100 m. The insulated electrical conductor may have an initial breakdown voltage, over a substantially continuous length of at least about 100 m, of at least about 60 volts per mil of the electrical insulator thickness (about 2400 volts per mm of the electrical insulator thickness) at about 1300° F. (about 700° C.) and about 60 Hz. The insulated electrical conductor may be capable of being coiled around a radius of about 100 times a diameter of the insulated electrical conductor. The outer electrical conductor may have a yield strength based on a 0.2% offset of about 100 kpsi.

Abstract: Method and systems (e.g., for use in hearing aids, IAPs, etc) to process an audio signal include receiving an audio signal input; separating the audio signal input into a plurality of frequency bands; and compressing each of the plurality of frequency bands. Compressing each respective frequency band of the plurality of frequency bands may include applying a time-varying gain to each respective frequency band based on a suppressive level for the respective frequency band resulting in a compressed respective frequency band (e.g., wherein the suppressive level for the respective frequency band is dependent on the audio signal input level of one or more frequency bands adjacent to the respective frequency band to which the gain is applied). The compressed respective frequency bands may be combined for use in providing an audio signal.

Abstract: An on-demand vapour generator includes a vapour chamber configured to produce a vapour and a vapour absorption assembly configured to receive flows of vapour from the vapour chamber. The vapour absorption assembly includes a first vapour-permeable passage having a passage outlet and at least one second vapour-permeable passage that is closed. When vapour absorption assembly receives a flow of vapour from the vapour chamber, the flow of vapour passes through the first vapour-permeable passage to the passage outlet at least substantially without absorption of vapour from the flow of vapour. However, when a flow of vapour is not received from the vapour chamber, vapour entering the vapour absorption assembly from the vapour chamber passes into the first vapour-permeable passage and the at least one second vapour-permeable passage and is at least substantially absorbed.

Abstract: Methods, systems, and techniques for federating operations, in an optimized way using wide area networks are provided. Example systems provide an API for generating and handling federated requests as an aggregation. In one example Wide Area Network Aggregation System, WANAS provides an API, a connection manager, and connection iterators to manage inter-site connections and requests, and inter-pod requests and messaging. These components cooperate to distribute a task across multiple physically disparate sites using a representative connection to the site and fan out of requests to other pods within the site.

Abstract: Methods, systems, and techniques for federating operations, in an optimized way using wide area networks are provided. Example systems provide an API for generating and handling federated requests as an aggregation. In one example Wide Area Network Aggregation System, WANAS provides an API, a connection manager, and connection iterators to manage inter-site connections and requests, and inter-pod requests and messaging. These components cooperate to distribute a task across multiple physically disparate sites using a representative connection to the site and fan out of requests to other pods within the site.

Abstract: A novel display surface framing and support apparatus capable of temporarily or permanently securing canvas art and other substrates in a taunt manner without damaging the display surface. Upon assembly, the structural members join in a self-squaring fashion creating a square or rectangular frame. In preferred embodiments, the framing and support apparatus generally comprises four frame members which are substantially three sided in profile, and four corner joiners that are inserted into the ends of each frame member and being secured with a plurality of fastening means. The periphery of the display surface wraps over and around the frame members and is secured into a securement groove that is continuous along each frame member. In some embodiments, a spline element may be used to press the display surface into the securement groove of each frame member to thereby fix the display surface to the apparatus in a taunt fashion.

Abstract: Systems and techniques for cleaning a corona discharge point are described. A controller (150) can be operatively coupled to a corona discharge point (108) to control the operation of the corona discharge point (1089. The controller (150) and the corona discharge point (108) can be included with, for example, an ion mobility spectrometry (IMS) system (100). The controller (150) can be used to operate the corona discharge point (108) at an operating voltage for a first time interval, with or without an additional higher pulse voltage, to produce a corona discharge, and to operate the corona discharge point (108) at a cleaning voltage greater than the operating voltage for a second time interval subsequent to the first time interval to produce a corona discharge.

Abstract: A functional biologically active particle conjugate useful for diagnosis and treating cancer as a bioportal comprises a nanoscale particle having associated therewith an intracellular targeting ligand comprising a PNA, or another nuclease resistant oligonucleotide analog such as MOE-mRNA (2?-methoxyethyl mRNA) or LNA (locked nucleic acid), having a sequence that binds selectively to an uniquely expressed or overexpressed mRNA specific to the cancer or disease state in a living mammal. In one aspect the uniquely overexpressed target specific to the cancer or disease state is the unr mRNA which can be targeted by the antisense sequence PNA50.

Abstract: A non-transitory processor-readable medium storing code representing instructions to cause a processor to perform a process includes code to cause the processor to receive a set of indications of allowed behavior associated with an application. The processor is also caused to initiate an instance of the application within a sandbox environment. The processor is further caused to receive, from a monitor module associated with the sandbox environment, a set of indications of actual behavior of the instance of the application in response to initiating the instance of the application within the sandbox environment. The processor is also caused to send an indication associated with an anomalous behavior if at least one indication from the set of indications of actual behavior does not correspond to an indication from the set of indications of allowed behavior.

Abstract: A system for assessing one or more temperatures along an insulated conductor in an opening in a subsurface formation includes an insulated conductor with a length comprising at least two sections of insulation with different capacitances. The sections with the different capacitances include different takeoff temperatures for at least one dielectric property of the insulation.

Abstract: A novel display surface framing and support apparatus capable of temporarily or permanently securing canvas art and other substrates in a taunt manner without damaging the display surface. Upon assembly, the structural members join in a self-squaring fashion creating a square or rectangular frame. In preferred embodiments, the framing and support apparatus generally comprises four frame members which are substantially three sided in profile, and four corner joiners that are inserted into the ends of each frame member and being secured with a plurality of fastening means. The periphery of the display surface wraps over and around the frame members and is secured into a securement groove that is continuous along each frame member. In some embodiments, a spline element may be used to press the display surface into the securement groove of each frame member to thereby fix the display surface to the apparatus in a taunt fashion.

Abstract: A system for assessing one or more temperatures in an opening in a subsurface formation includes an electrical conductor and electrical insulation at least partially surrounding the electrical conductor. The electrical insulation includes magnesium oxide and a ferroelectric material. An electrically conductive sheath at least partially surrounds the electrical insulation. A profile of one or more dielectric properties of the electrical insulation along a length of the electrical insulation is assessed during use to assess a temperature profile with spatial resolution along the length of the electrical insulation.

Abstract: A nicotine-containing pharmaceutical product configured for insertion into the mouth of a user of that product is provided. The product can have an outer water-permeable pouch, a nicotine-containing pharmaceutical composition situated within the outer water-permeable pouch, and product identifying information relating to the nicotine-containing pharmaceutical composition. The information can be presented such that a user of the product can discern the identifying information by visually inspecting the product and thereby differentiate or identify certain nicotine-containing pharmaceutical products. The product identifying can be, for example, printed, imprinted or dyed on the outer water-permeable pouch, positioned within the outer water-permeable pouch, or attached to the outer water-permeable pouch.

Abstract: A fitting for coupling an end of a first insulated conductor to an end of a second insulated conductor is described. The fitting includes a first splice housing placed over the end of the first insulated conductor and coupled to the first insulated conductor. The fitting also includes a second splice housing placed over the end of the second insulated conductor and coupled to the second insulated conductor. A sleeve is located over the end of the second insulated conductor and adjacent to the second splice housing. An interior volume of the fitting is substantially filled with electrically insulating material. The interior volume of the fitting is reduced such that the electrically insulating material substantially filling the interior volume is compacted.

Abstract: A method for fabricating a quadrupole mass filter (QMF) or quadrupole ion trap (QIT) capable of generating a hyperbolic electric field. The method comprises: (a) cutting four elongate erodible metal workpieces axially at opposing extremities; (b) parallel mounting the four elongate erodible metal workpieces axially in an elongate slot in an insulating housing in a mutually spaced apart disposition such that an axial bore is formed therebetween whereby a first part of each elongate erodible metal workpiece is freely inward facing and the cutting forms a recess remote from the axis of the insulating housing; (c) electrically connecting the erodible metal workpieces; and (d) generating electrical discharges between the erodible metal workpiece and a wire electrode as the wire electrode passes through the axial bore to erode the erodible metal of the first part of the erodible metal workpiece to a hyperbolic profile.

Abstract: The present invention relates to a process for fabricating a quadrupole mass spectrometer (QMS) component, to a monolithic quadrupole mass spectrometer or a component thereof, to a quadrupole mass filter (QMF) or quadrupole ion trap (QIT) capable of generating a hyperbolic electric field and to a modular quadrupole mass spectrometer (QMS) assembly.

Abstract: A functional biologically active particle conjugate useful for diagnosis and treating cancer as a bioportal comprises a nanoscale particle having associated therewith an intracellular targeting ligand comprising a PNA, or another nuclease resistant oligonucleotide analog such as MOE-mRNA (2?-methoxyethyl mRNA) or LNA (locked nucleic acid), having a sequence that binds selectively to an uniquely expressed or overexpressed mRNA specific to the cancer or disease state in a living mammal. In one aspect the uniquely overexpressed target specific to the cancer or disease state is the unr mRNA which can be targeted by the antisense sequence PNA50.

Abstract: The present invention is a cooling vest which has a type of phase change heat sink that particularly lends itself to layering of the heat sinks on the body. The heat sinks are quilted and have a means for the transportation of moisture through them and the means of transportation of air through channels in the quilted heat sinks. Thus they can remove moisture from the surface of the body and remain flexible.

Abstract: Methods for assessing a temperature in an opening in a subsurface formation are described herein. A method may include assessing one or more dielectric properties along a length of an insulated conductor located in the opening and assessing one or more temperatures along the length of the insulated conductor based on the one or more assessed dielectric properties.