Patents by Inventor Stephen Valazza

Stephen Valazza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Organic Compounds
    Publication number: 20160338978
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1 Preceptor modulator.
    Type: Application
    Filed: August 4, 2016
    Publication date: November 24, 2016
    Applicant: Novartis AG
    Inventors: Michael AMBUHL, Jutta BEYER, Begona CARRENO-GOMEZ, Colleen RUEGGER, Stephen VALAZZA
  • ORGANIC COMPOUNDS
    Publication number: 20140227358
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1P receptor modulator.
    Type: Application
    Filed: April 17, 2014
    Publication date: August 14, 2014
    Applicant: NOVARTIS AG
    Inventors: Michael AMBUHL, Jutta BEYER, Begona CARRENO-GOMEZ, Colleen RUEGGER, Stephen VALAZZA
  • Galenical formulations of organic compounds
    Patent number: 8613949
    Abstract: The present invention relates to a pharmaceutical oral fixed dose combination comprising a) a therapeutically effective amount of Aliskiren, or a pharmaceutically acceptable salt thereof, b) a therapeutically effective amount of Amlodipine, or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical oral fixed dose combination shows an in vitro dissolution of component (a) of 60% or less after 10 minutes and 98% or less after 20 minutes, and a dissolution profile of component (b) of 50% or more after 20 minutes, and 70% or more after 30 minutes at pH 2, said pharmaceutical oral fixed dose combination being bioequivalent, or close to reaching bioequivalence, to a free dose combination of Aliskiren and Amlodipine.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: December 24, 2013
    Assignee: Novartis AG
    Inventors: Stephen Valazza, Robert F Wagner, Sudha Vippagunta
  • ORGANIC COMPOUNDS
    Publication number: 20120288559
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1P receptor modulator.
    Type: Application
    Filed: July 19, 2012
    Publication date: November 15, 2012
    Inventors: Michael Ambühl, Jutta Beyer, Begona Carreno-Gomez, Colleen Ruegger, Stephen Valazza
  • Pharmaceutical compositions comprising fluvastatin
    Patent number: 8303987
    Abstract: Pharmaceutical compositions comprising fluvastatin, HPMC and optionally other pharmaceutical excipients which are colour-stable upon prolonged periods of storage.
    Type: Grant
    Filed: July 13, 2010
    Date of Patent: November 6, 2012
    Assignee: Novartis AG
    Inventors: Oskar Kalb, Stephen Valazza
  • GALENICAL FORMULATIONS OF ORGANIC COMPOUNDS
    Publication number: 20110165240
    Abstract: The present invention relates to a pharmaceutical oral fixed dose combination comprising a) a therapeutically effective amount of Aliskiren, or a pharmaceutically acceptable salt thereof, b) a therapeutically effective amount of Amlodipine, or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical oral fixed dose combination shows an in vitro dissolution of component (a) of 60% or less after 10 minutes and 98% or less after 20 minutes, and a dissolution profile of component (b) of 50% or more after 20 minutes, and 70% or more after 30 minutes at pH 2, said pharmaceutical oral fixed dose combination being bioequivalent, or close to reaching bioequivalence, to a free dose combination of Aliskiren and Amlodipine.
    Type: Application
    Filed: September 22, 2009
    Publication date: July 7, 2011
    Inventors: Stephen Valazza, Robert F. Wagner, Sudha Vippagunta
  • PHARMACEUTICAL COMPOSITIONS COMPRISING FLUVASTATIN
    Publication number: 20100303919
    Abstract: Pharmaceutical compositions comprising fluvastatin, HPMC and optionally other pharmaceutical excipients which are colour-stable upon prolonged periods of storage.
    Type: Application
    Filed: July 13, 2010
    Publication date: December 2, 2010
    Inventors: OSKAR Kalb, Stephen Valazza
  • ORGANIC COMPOUNDS
    Publication number: 20100040678
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1P receptor modulator.
    Type: Application
    Filed: September 25, 2007
    Publication date: February 18, 2010
    Inventors: Michael Ambuhl, Jutta Beyer, Begona Carreno-Gomez, Colleen Ruegger, Stephen Valazza
  • Pharmaceutical compositions comprising fluvastatin
    Publication number: 20060127474
    Abstract: Pharmaceutical compositions comprising fluvastatin, HPMC and optionally other pharmaceutical excipients which are colour-stable upon prolonged periods of storage.
    Type: Application
    Filed: February 3, 2006
    Publication date: June 15, 2006
    Inventors: Oskar Kalb, Stephen Valazza
  • Pharmaceutical compositions comprising fluvastatin
    Publication number: 20030171419
    Abstract: Pharmaceutical compositions comprising fluvastatin, HPMC and optionally other pharmaceutical excipients which are colour-stable upon prolonged periods of storage.
    Type: Application
    Filed: October 15, 2002
    Publication date: September 11, 2003
    Inventors: Oskar Kalb, Stephen Valazza