Patents by Inventor Stephen W. Santoro

Stephen W. Santoro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymes, cells and methods for site specific recombination at asymmetric sites
    Publication number: 20090217400
    Abstract: The present invention relates to enzymes, compositions and methods for catalyzing asymmetric recombination of non-palindromic recombination sites in a cell free system, in isolated cells or in living organisms. The enzymes and methods of the invention are suitable for mediating specific recombinations between DNA sequences comprising specific recombination sites without being limited to strict palindromic symmetry within each recombination site.
    Type: Application
    Filed: February 24, 2005
    Publication date: August 27, 2009
    Applicants: State of Israel, Ministry of Agriculture, Agricultural Research Organization, The Scripps Research Institute
    Inventors: Nir Carmi, Yoram Eyal, David Gidoni, Peter G. Schultz, Stephen W. Santoro
  • Enzymatic DNA molecules that contain modified nucleotides
    Patent number: 6110462
    Abstract: The present invention discloses catalytic or enzymatic DNA molecules that contain a modified nucleotide and that are capable of cleaving nucleic acid sequences or molecules, particularly RNA, in a site-specific manner, as well as compositions including same. Methods of making and using the disclosed enzymes and compositions are also disclosed.
    Type: Grant
    Filed: March 3, 1999
    Date of Patent: August 29, 2000
    Assignee: The Scripps Research Institute
    Inventors: Carlos F. Barbas, Gerald Joyce, Stephen W. Santoro, Sakthivel Kandasamy