Patents by Inventor Steve A. Orndorff

Steve A. Orndorff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11052060
    Abstract: Compounds and compositions useful in methods of treating, ameliorating, or inhibiting the development of autoimmune diseases or Celiac disease by modulating the binding of DQ8 MHC class II molecules to antigenic peptides or fragments of antigenic peptides.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: July 6, 2021
    Assignees: The Regents of the University of Colorado, a body corporate, ImmunoMolecular Therapeutics, Inc.
    Inventors: Steve Orndorff, Aaron Michels
  • Patent number: 11013707
    Abstract: Methods of administering methyldopa to a subject in a fasting state to increase bioavailability of the methyldopa.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: May 25, 2021
    Assignees: The Regents of the University of Colorado, a body corporate, ImmunoMolecular Therapeutics, Inc.
    Inventors: Steve Orndorff, Aaron Michels
  • Publication number: 20190290607
    Abstract: Methods of administering methyldopa to a subject in a fasting state to increase bioavailability of the methyldopa.
    Type: Application
    Filed: March 23, 2018
    Publication date: September 26, 2019
    Inventors: Steve Orndorff, Aaron Michels
  • Publication number: 20190262301
    Abstract: Compounds and compositions useful in methods of treating, ameliorating, or inhibiting the development of autoimmune diseases or Celiac disease by modulating the binding of DQ8 MHC class II molecules to antigenic peptides or fragments of antigenic peptides.
    Type: Application
    Filed: March 19, 2019
    Publication date: August 29, 2019
    Inventors: Steve Orndorff, Aaron Michels
  • Patent number: 9820957
    Abstract: Methods of treating, ameliorating, or inhibiting the development of autoimmune diseases by modulating the binding of MHC class II molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease. The binding may be modulated by the administration of D-?-methyldopa, or pharmaceutical compositions comprising therapeutically effective amounts of D-?-methyldopa.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: November 21, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Steve Orndorff, Aaron Michels, Peter Gottlieb
  • Publication number: 20170273927
    Abstract: Methods of treating, ameliorating, or inhibiting the development of autoimmune diseases by modulating the binding of MHC class II molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease. The binding may be modulated by the administration of D-?-methyldopa, or pharmaceutical compositions comprising therapeutically effective amounts of D-?-methyldopa.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 28, 2017
    Inventors: Steve Orndorff, Aaron Michels, Peter Gottlieb
  • Publication number: 20060189545
    Abstract: Methods and composition for treating or preventing, the occurrence of senile dementia of the Alzheimer's type, or other conditions arising from reduced neuronal metabolism and leading to lessened cognitive function are described. In a preferred embodiment the administration of novel esterified saccharide compounds to said patient at a level to produce an improvement in cognitive ability.
    Type: Application
    Filed: March 8, 2004
    Publication date: August 24, 2006
    Inventors: Samuel Henderson, Steve Orndorff, Lawrence Melvin
  • Patent number: 5360730
    Abstract: The present invention is directed toward a process for producing zeaxanthin which includes mutating algal microorganisms, selecting from said mutated microorganisms a microorganism capable of producing zeaxanthin, culturing the selected microorganism in an effective medium to produce zeaxanthin, and recovering zeaxanthin produced by the selected microorganism. The present invention also provides microorganisms capable of producing zeaxanthin, formulations containing zeaxanthin produced by the disclosed process and the use of such formulations to enhance pigmentation and to reduce damage caused by reactive oxygen species and phototoxic molecules.
    Type: Grant
    Filed: October 15, 1991
    Date of Patent: November 1, 1994
    Assignee: Universal Foods Corporation
    Inventors: Steve A. Orndorff, Elizabeth A. Campbell, Richard D. Medwid
  • Patent number: 4757015
    Abstract: Phenylalanine ammonia-lyase (PAL) producing Rhodotorula graminis, high PAL specific activity, strain GX 6000 its progeny, and PAL producing mutants thereof can be utilized for phenylalanine production from cinnamate. In this strain, PAL can be induced synergistically by phenylalanine and leucine or isoleucine.
    Type: Grant
    Filed: August 11, 1986
    Date of Patent: July 12, 1988
    Assignee: Genex Corporation
    Inventors: Steve A. Orndorff, Don R. Durham
  • Patent number: 4677072
    Abstract: A yeast culture medium contains glucose, yeast extract, buffers, alkaline earth metal salts, and antibiotics, has a pH of 4.3 to 4.7. Yeast strains of the genus Rhodotorula, obtained from water and soil samples, are useful as desaturase enzymes, especially for the conversion of oleic acid to linoleic acid in improved yields using the yeast culture medium.
    Type: Grant
    Filed: February 28, 1985
    Date of Patent: June 30, 1987
    Assignee: Westvaco Corporation
    Inventor: Steve A. Orndorff
  • Patent number: 4478683
    Abstract: A method of killing and inhibiting the growth of microorganisms in industrial process streams comprises the addition of an enzymatically catalyzed biocide system utilizing a microbial or plant dehydrogenase enzyme such as peroxidase or laccase in the presence of an oxidant such as hydrogen peroxide or oxygen to oxidize phenolic compounds found in or added to the process streams to produce oxidation products that are toxic to microorganisms.
    Type: Grant
    Filed: September 27, 1982
    Date of Patent: October 23, 1984
    Assignee: Westvaco Corporation
    Inventor: Steve A. Orndorff
  • Patent number: 4370199
    Abstract: A method of killing and inhibiting the growth of microorganisms in industrial process streams comprises the addition of an enzymatically catalyzed biocide system utilizing a microbial or plant dehydrogenase enzyme such as peroxidase or laccase in the presence of an oxidant such as hydrogen peroxide or oxygen to oxidize halide salts, or phenolic compounds found in or added to the process streams to produce oxidation products that are toxic to microorganisms.
    Type: Grant
    Filed: November 9, 1981
    Date of Patent: January 25, 1983
    Assignee: Westvaco Corporation
    Inventor: Steve A. Orndorff