Patents by Inventor Steve Lambert Klopman

Steve Lambert Klopman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calcium controlled activation of platelets via electrical stimulation
    Patent number: 11591590
    Abstract: The present disclosure relates to the generation of an activated platelet product in which one or more of the presence or absence of clots, the timing of clot formation (if present), and/or the mechanical strength of clots (if present) is controlled by the presence or concentration of calcium ions during the activation process. In certain embodiments, the calcium ion concentration is controlled in the presence of pulsed electric fields or a chemical activator (e.g., thrombin) as part of the activation process.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: February 28, 2023
    Assignee: General Electric Company
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Steve Lambert Klopman
  • CALCIUM CONTROLLED ACTIVATION OF PLATELETS VIA ELECTRICAL STIMULATION
    Publication number: 20200239868
    Abstract: The present disclosure relates to the generation of an activated platelet product in which one or more of the presence or absence of clots, the timing of clot formation (if present), and/or the mechanical strength of clots (if present) is controlled by the presence or concentration of calcium ions during the activation process. In certain embodiments, the calcium ion concentration is controlled in the presence of pulsed electric fields or a chemical activator (e.g., thrombin) as part of the activation process.
    Type: Application
    Filed: April 16, 2020
    Publication date: July 30, 2020
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Steve Lambert Klopman
  • Calcium controlled activation of platelets via electrical stimulation
    Patent number: 10633645
    Abstract: The present disclosure relates to the generation of an activated platelet product in which one or more of the presence or absence of clots, the timing of clot formation (if present), and/or the mechanical strength of clots (if present) is controlled by the presence or concentration of calcium ions during the activation process. In certain embodiments, the calcium ion concentration is controlled in the presence of pulsed electric fields or a chemical activator (e.g., thrombin) as part of the activation process.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: April 28, 2020
    Assignee: General Electric Company
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Steve Lambert Klopman
  • CALCIUM CONTROLLED ACTIVATION OF PLATELETS VIA ELECTRICAL STIMULATION
    Publication number: 20170191052
    Abstract: The present disclosure relates to the generation of an activated platelet product in which one or more of the presence or absence of clots, the timing of clot formation (if present), and/or the mechanical strength of clots (if present) is controlled by the presence or concentration of calcium ions during the activation process. In certain embodiments, the calcium ion concentration is controlled in the presence of pulsed electric fields or a chemical activator (e.g., thrombin) as part of the activation process.
    Type: Application
    Filed: December 30, 2015
    Publication date: July 6, 2017
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Steve Lambert Klopman