Abstract: In one example, a structure for surface enhanced Raman spectroscopy includes a cluster of metal nanoparticles in a hole.

Abstract: In an example implementation, a substance detection device includes a chamber with chamber walls, a chamber top, and a chamber bottom. A substrate comprises imprinted nanostructures positioned within the chamber, and the substrate is coupled to the chamber walls to form the chamber bottom. An inert gas is sealed within the chamber.

Abstract: In one example, an analyte detection package includes a substrate, surface-enhanced luminescence (SEL) structures extending from the substrate and a low wettability housing. The SEL structures have a first wettability for a given liquid. The low wettability housing extends from the substrate to form a chamber between the housing of the substrate about the SEL structures to receive an analyte containing solution. The housing has an inner surface adjacent the chamber, wherein the inner surface has a second wettability for the given liquid less than the first wettability.

Abstract: In an example implementation, a substance detection device includes a substrate having nanoimprinted chamber walls and nanostructures. The chamber walls define a chamber and the nanostructures are positioned within the chamber to react to a substance introduced into the chamber. A two-dimensional (2D) orifice plate is affixed to the chamber walls and forms a top side of the chamber.

Abstract: Provided in one example is an analyte detection apparatus that includes surface enhanced luminescence (SEL) structure. A dielectric layer underlies the SEL structure. An electric field generating base underlies the dielectric layer. The electric field generating base is to apply an electric field about the SEL structures to attract charged ions to the SEL structures.

Abstract: A system includes an illumination source, a detector and a processor. The detector acquires spectral measurements of a sample under test under at least one varying condition. The processor processes the measurements to generate at least one spectral representation that includes Raman spectra and at least one spectral representation that includes non-Raman spectra.

Abstract: A surface enhanced luminescence (SEL) sensing stage may include a matrix and plasmonically active nanostructures retained within the matrix, wherein no greater than 10% of the plasmonically active nanostructures consist of a single unagglomerated plasmonically active nano particle.

Abstract: A microfluidic chip may include a substrate, chamber supported by the substrate, a sacrificial material in the chamber, a spectroscopically active nano particle assembly anchored within the chamber by the sacrificial material and a fluid supply port connected to the chamber. Each spectroscopically active nano particle assembly may include a cluster of nanoparticles.

Abstract: In an example implementation, a method of fabricating a microfluidic channel filter, includes depositing an imprintable material in a microfluidic channel, pressing an imprint stamp with a filter pattern into the imprintable material, curing the imprintable material, and removing the imprint stamp from the imprintable material.

Abstract: In an example implementation, a substance detection device includes a chamber with chamber walls, a chamber top, and a chamber bottom. A substrate comprises imprinted nanostructures positioned within the chamber, and the substrate is coupled to the chamber walls to form the chamber bottom. An inert gas is sealed within the chamber.

Abstract: In an example implementation, a substance detection device includes a substrate having nanoimprinted chamber walls and nanostructures. The chamber walls define a chamber and the nanostructures are positioned within the chamber to react to a substance introduced into the chamber. A two-dimensional (2D) orifice plate is affixed to the chamber walls and forms a top side of the chamber.

Abstract: In an example implementation, a substance detection method includes sensing for fluid in a chamber of a substance detection device. When fluid is sensed in the chamber, the method includes sensing again for fluid in the chamber. When no fluid is sensed in the chamber, the method includes initiating a substance detection process.

Abstract: In one example, an analyte detection package includes a substrate, surface-enhanced luminescence (SEL) structures extending from the substrate and a low wettability housing. The SEL structures have a first wettability for a given liquid. The low wettability housing extends from the substrate to form a chamber between the housing of the substrate about the SEL structures to receive an analyte containing solution. The housing has an inner surface adjacent the chamber, wherein the inner surface has a second wettability for the given liquid less than the first wettability.

Abstract: Provided in one example is an analyte detection apparatus that includes surface enhanced luminescence (SEL) structure. A dielectric layer underlies the SEL structure. An electric field generating base underlies the dielectric layer. The electric field generating base is to apply an electric field about the SEL structures to attract charged ions to the SEL structures.

Abstract: In one example, a structure for surface enhanced Raman spectroscopy includes a cluster of metal nanoparticles in a hole.

Abstract: An apparatus for performing a sensing application may a substrate having a plurality of nano-fingers positioned to receive the dispensed solution , first and second reservoirs, first and second dispensers to dispense first and second solutions from the first and second reservoirs onto first and second subsets of the plurality of nano-fingers. The plurality of nano-fingers are flexible, such that the plurality of nano-fingers are configurable with respect to each other. The apparatus may include an illumination source to illuminate the first and second solutions and an analyte introduced around the plurality of nano-fingers, wherein light is to be emitted from the analyte in response to being illuminated. The apparatus may include a detector to detect the light emitted from the analyte.

Abstract: An implantable nanosensor includes a stent to be implanted inside a fluid conduit. The stent has a well in a surface of the stent. The implantable nanosensor further includes a nanoscale-patterned sensing substrate disposed in the well. The nanoscale-patterned sensing substrate is to produce an optical scattering response signal indicative of a presence of an analyte in a fluid carried by the fluid conduit when interrogated by an optical stimulus signal.

Abstract: An apparatus for performing a sensing application may a substrate having a plurality of nano-fingers positioned to receive the dispensed solution , first and second reservoirs, first and second dispensers to dispense first and second solutions from the first and second reservoirs onto first and second subsets of the plurality of nano-fingers. The plurality of nano-fingers are flexible, such that the plurality of nano-fingers are configurable with respect to each other. The apparatus may include an illumination source to illuminate the first and second solutions and an analyte introduced around the plurality of nano-fingers, wherein light is to be emitted from the analyte in response to being illuminated. The apparatus may include a detector to detect the light emitted from the analyte.

Abstract: An apparatus for performing a sensing application includes a reservoir to contain a solution, a dispenser to dispense the solution from the reservoir, and a substrate having a plurality of nano-fingers positioned to receive the dispensed solution, in which the plurality of nano-fingers are flexible, such that the plurality of nano-fingers are configurable with respect to each other. The apparatus also includes an illumination source to illuminate the received solution, an analyte introduced around the plurality of nano-fingers, and the plurality of nano-fingers, in which light is to be emitted from the analyte in response to being illuminated. The apparatus further includes a detector to detect the light emitted from the analyte.

Abstract: A scattering spectroscopy nanosensor includes a nanoscale-patterned sensing substrate to produce an optical scattering response signal indicative of a presence of an analyte when interrogated by an optical stimulus. The scattering spectroscopy nanosensor further includes a protective covering to cover and protect the nanoscale-patterned sensing substrate. The protective covering is to be selectably removed by exposure to an optical beam incident on the protective covering. The protective covering is to prevent the analyte from interacting with the nanoscale-patterned sensing substrate prior to being removed.