Abstract: A TDI scanner including a dynamically programmable focal plane array including a two-dimensional array of detectors arranged in a plurality of columns and a plurality of rows, the array being divided into a plurality of banks separated from one another by gap regions, each bank including a plurality of sub-banks, and each sub-bank including at least one row of detectors, a ROIC coupled to the focal plane array and configured to combine in a TDI process outputs from detectors in each column of detectors in each sub-bank, and a controller configured to program the focal plane array to selectively and dynamically set characteristics of the focal plane array, the characteristics including a size and a location within the two-dimensional array of each of the plurality of sub-banks and the gap regions, the size corresponding to a number of rows of detectors included in the respective sub-bank or gap region.

Abstract: A TDI scanner including a dynamically programmable focal plane array including a two-dimensional array of detectors arranged in a plurality of columns and a plurality of rows, the array being divided into a plurality of banks separated from one another by gap regions, each bank including a plurality of sub-banks, and each sub-bank including at least one row of detectors, a ROIC coupled to the focal plane array and configured to combine in a TDI process outputs from detectors in each column of detectors in each sub-bank, and a controller configured to program the focal plane array to selectively and dynamically set characteristics of the focal plane array, the characteristics including a size and a location within the two-dimensional array of each of the plurality of sub-banks and the gap regions, the size corresponding to a number of rows of detectors included in the respective sub-bank or gap region.

Abstract: A TDI scanner including a dynamically programmable focal plane array including a two-dimensional array of detectors arranged in a plurality of columns and a plurality of rows, the array being divided into a plurality of banks separated from one another by gap regions, each bank including a plurality of sub-banks, and each sub-bank including at least one row of detectors, a ROIC coupled to the focal plane array and configured to combine in a TDI process outputs from detectors in each column of detectors in each sub-bank, and a controller configured to program the focal plane array to selectively and dynamically set characteristics of the focal plane array, the characteristics including a size and a location within the two-dimensional array of each of the plurality of sub-banks and the gap regions, the size corresponding to a number of rows of detectors included in the respective sub-bank or gap region.

Abstract: A TDI scanner including a dynamically programmable focal plane array including a two-dimensional array of detectors arranged in a plurality of columns and a plurality of rows, the array being divided into a plurality of banks separated from one another by gap regions, each bank including a plurality of sub-banks, and each sub-bank including at least one row of detectors, a ROIC coupled to the focal plane array and configured to combine in a TDI process outputs from detectors in each column of detectors in each sub-bank, and a controller configured to program the focal plane array to selectively and dynamically set characteristics of the focal plane array, the characteristics including a size and a location within the two-dimensional array of each of the plurality of sub-banks and the gap regions, the size corresponding to a number of rows of detectors included in the respective sub-bank or gap region.

Abstract: According to one aspect, embodiments herein provide a unit cell circuit comprising a photodetector configured to generate a photo-current in response to receiving light, a first integration capacitor configured to accumulate charge corresponding to the photo-current, a second integration capacitor configured to accumulate charge corresponding to the photo-current, a charge diverting switch coupled to the photodetector and configured to selectively couple the first integration capacitor to the second integration capacitor and divert the photo-current to the second integration capacitor in response to a voltage across the first integration capacitor exceeding a threshold level, and read-out circuitry coupled to the first integration capacitor and the charge diverting switch and configured to read-out a first voltage sample from the first integration capacitor corresponding to charge accumulated on the first integration capacitor and to read-out a second voltage sample from the second integration capacitor corre

Abstract: According to one aspect, embodiments herein provide a unit cell circuit comprising a photodetector configured to generate a photo-current in response to receiving light, a first integration capacitor configured to accumulate charge corresponding to the photo-current, a second integration capacitor configured to accumulate charge corresponding to the photo-current, a charge diverting switch coupled to the photodetector and configured to selectively couple the first integration capacitor to the second integration capacitor and divert the photo-current to the second integration capacitor in response to a voltage across the first integration capacitor exceeding a threshold level, and read-out circuitry coupled to the first integration capacitor and the charge diverting switch and configured to read-out a first voltage sample from the first integration capacitor corresponding to charge accumulated on the first integration capacitor and to read-out a second voltage sample from the second integration capacitor corre

Abstract: A combined scanning and staring (SCARING) focal plane array (FPA) imaging system having a plurality of modes of operation is provided. In one example, the SCARING FPA system includes a photodetector array with a plurality of photodetectors arranged in a plurality of photodetector rows, a readout integrated circuit (ROIC) coupled to the photodetector array, and a processor coupled to the ROIC. The processor coupled to the ROIC is configured to dynamically configure the SCARING FPA between a scanning mode of operation and a staring mode of operation.

Abstract: A combined scanning and staring (SCARING) focal plane array (FPA) imaging system having a plurality of modes of operation is provided. In one example, the SCARING FPA system includes a photodetector array with a plurality of photodetectors arranged in a plurality of photodetector rows, a readout integrated circuit (ROIC) coupled to the photodetector array, and a processor coupled to the ROIC. The processor coupled to the ROIC is configured to dynamically configure the SCARING FPA between a scanning mode of operation and a staring mode of operation.

Abstract: Proper selection and centering of an intraocular lens (IOL) is provided. An image of an eye, which may be captured during pre-operative tests and provided to a program operable to calculate the power and axis orientation of the IOL, is used to determine the location and orientation of the IOL. This produces an output or placement guide used to properly center and orient an IOL within the eye.

Abstract: Proper selection and centering of an intraocular lens (IOL) is provided. An image of an eye, which may be captured during pre-operative tests and provided to a program operable to calculate the power and axis orientation of the IOL, is used to determine the location and orientation of the IOL. This produces an output or placement guide used to properly center and orient an IOL within the eye.

Abstract: A system and method for tracking ocular changes during a surgical procedure include directing an eye-safe optical beam toward an undilated, unparalyzed eye. A reflected optical beam is detected, and measurements are performed based upon data contained in the reflected optical beam of at least one geometric parameter of the eye at a predetermined frequency, and from them is calculated a change in the at least one geometric parameter. The calculated change is used to dynamically adjust the directing of laser beam shots during the surgery.

Abstract: An assay compound or a salt thereof for assaying the activity of an enzyme inside a metabolically active whole cell is disclosed. The assay compound includes a leaving group and an indicator group. The leaving group is selected from the group comprising amino acids, peptides, saccharides, sulfates, phosphates, esters, phosphate esters, nucleotides, polynucleotides, nucleic acids, pyrimidines, purines, nucleosides, lipids and mixtures thereof. The indicator group is selected from compounds which have a first state when joined to the leaving group, and a second state when the leaving group is cleaved from the indicator group by the enzyme. Preferably, the indicator compounds are rhodamine 110, rhodol, and fluorescein and analogs of these compounds. A method of synthesizing the compound as well as methods of using these compounds to measure enzyme activity are also disclosed.