Abstract: The present invention provides methods for inhibiting JAK2 tyrosine kinase. Further, the present invention also provides methods of treating or preventing myeloproliferative disorders.

Abstract: The present invention provides methods for inhibiting RET tyrosine kinase. Further, the present invention also provides methods of treating or preventing thyroid cancer.

Abstract: The present invention provides methods for inhibiting JAK2 tyrosine kinase. Further, the present invention also provides methods of treating or preventing myeloproliferative disorders.

Abstract: A system and method is provided for learning data values over time as they are entered by a user on a form such as a web page form. An Internet web browser can be modified to suggest previously used data values for any form field that is the same as or similar to a previously used form field. Application programs that use the web browser can gain access to previously used form field values even if they have no knowledge of the field names. Software in a web browser associates field names across different Universal Resource Locators (URLs), so that when a user enters a value into a field (e.g., username) at a first web site, that same value can be automatically suggested when the user displays a different form on a different web site that uses the same field name.

Abstract: A client-based system has a scheduling subsystem to schedule a time to obtain the Web content from the server. When the client reaches the scheduled time, the scheduling subsystem generates an event notification that contains sufficient information explaining how to retrieve the Web content. The client-based system has a delivery subsystem that is responsive to the event notification to obtain the Web content at the time set by the scheduling subsystem. The delivery subsystem preferably has multiple delivery modules that enable different types of distribution mechanism. In addition to the Web content or data itself, the delivery subsystem obtains an index to the Web content. The index summarizes the Web content to facilitate local search and find tasks. The index and Web content are stored in a cache at the client. An indexing subsystem presents the index to a user and enables the user to select from the index portions of the Web content that they prefer.