Patents by Inventor Steven Kok Hing Foung

Steven Kok Hing Foung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human T-cell lymphotropic virus type II envelope protein and human monoclonal antibodies specific therefor
    Patent number: 6270959
    Abstract: Isolated and purified envelope protein of HTLV-I is provided devoid of non-envelope protein of HTLV-I and having substantially the same conformation as the envelope protein in native HTLV-I. The protein is produced recombinantly using a dual vaccinia/T7 polymerase system. Non-glycosylated and glycosylated forms of the protein are produced. Glycosylated forms are recognized by antibodies specific for the envelope protein of HTLV-I. Monoclonal antibodies are provided which are specific for the HTLV-I envelope protein and non-binding to HTLV-I envelope protein in denatured form. The HTLV-I envelope protein is cross-reactive with antibodies of HTLV-II and STLV. The envelope protein is useful in diagnosis of infection by HTLV-I and HTLV-II.
    Type: Grant
    Filed: September 30, 1999
    Date of Patent: August 7, 2001
    Inventors: Gregory A. Dekaban, Jacqueline Arp, Steven Kok Hing Foung
  • Human T-cell lymphotropic virus type I envelope protein and human monoclonal antibodies specific therefor
    Patent number: 5961984
    Abstract: Isolated and purified envelope protein of HTLV-I is provided devoid of non-envelope protein of HTLV-I and having substantially the same conformation as the envelope protein in native HTLV-I. The protein is produced recombinantly using a dual vaccinia/T7 polymerase system. Non-glycosylated and glycosylated forms of the protein are produced. Glycosylated forms are recognized by antibodies specific for the envelope protein of HTLV-I. Monoclonal antibodies are provided which are specific for the HTLV-I envelope protein and non-binding to HTLV-I envelope protein in denatured form. The HTLV-I envelope protein is cross-reactive with antibodies of HTLV-II and STLV. The envelope protein is useful in diagnosis of infection by HTLV-I and HTLV-II.
    Type: Grant
    Filed: April 2, 1996
    Date of Patent: October 5, 1999
    Assignees: University of Western Ontario, Stanford University
    Inventors: Gregory A. Dekaban, Jacqueline Arp, Steven Kok Hing Foung