Patents by Inventor Steven Leigh
Steven Leigh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240136644Abstract: A power tool battery pack enclosure is configured to be coupled to battery pack receptacles of a plurality of power tools, each battery pack receptacle configured to removably receive a plurality of power tool battery packs. The enclosure includes a first clamshell member and a second clamshell member configured to be coupled around at least a portion of an exterior surface of each battery pack receptacle. Each of the first and second clamshell members have a top wall portion configured to be received over the exterior surface of the battery pack receptacle and a sidewall portion that extends downward from the top wall portion over at least a portion of the battery pack housing when the battery pack is received in the battery pack receptacle.Type: ApplicationFiled: December 22, 2023Publication date: April 25, 2024Inventors: Steven Jay WROBEL, Diane Leigh OLSON, David John THOMPSON, David Keith ESSLINGER, Michael VARIPATIS
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Patent number: 11963928Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.Type: GrantFiled: May 2, 2023Date of Patent: April 23, 2024Assignee: CORNING INCORPORATEDInventors: James Ernest Webb, Sinue Gomez-Mower, Weirong Jiang, Joseph Michael Matusick, Christie Leigh McCarthy, Connor Thomas O'Malley, John Stephen Peanasky, Shivani Rao Polasani, Steven Edward DeMartino, Michael Clement Ruotolo, Jr., Bryan James Musk, Jared Seaman Aaldenberg, Eric Lewis Allington, Douglas Miles Noni, Jr., Amber Leigh Tremper, Kristen Dae Waight, Kevin Patrick McNelis, Patrick Joseph Cimo, Christy Lynn Chapman, Robert Anthony Schaut, Adam Robert Sarafian
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Patent number: 11963929Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.Type: GrantFiled: May 2, 2023Date of Patent: April 23, 2024Assignee: CORNING INCORPORATEDInventors: Connor Thomas O'Malley, Sinue Gomez-Mower, Weirong Jiang, Joseph Michael Matusick, Christie Leigh McCarthy, Christy Lynn Chapman, John Stephen Peanasky, Shivani Rao Polasani, James Ernest Webb, Michael Clement Ruotolo, Jr., Bryan James Musk, Jared Seaman Aaldenberg, Eric Lewis Allington, Douglas Miles Noni, Jr., Amber Leigh Tremper, Kristen Dae Waight, Kevin Patrick McNelis, Patrick Joseph Cimo, Steven Edward DeMartino, Robert Anthony Schaut, Adam Robert Sarafian
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Patent number: 11931343Abstract: Compounds, such as compounds having Formula (I): wherein each variable is as described herein, that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.Type: GrantFiled: August 26, 2019Date of Patent: March 19, 2024Assignee: Arcus Biosciences, Inc.Inventors: Joel Beatty, Laurent Pierre Paul Debien, Samuel Lawrie Drew, Jeremy Fournier, Rebecca Louise Grange, Steven Donald Jacob, Jenna Leigh Jeffrey, Kenneth V. Lawson, Manmohan Reddy Leleti, Erick Allen Lindsey, Debashis Mandal, Jay Patrick Powers, Anh Thu Tran, Rhiannon Thomas-Tran, Xuelei Yan
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Publication number: 20220178900Abstract: A biorelevant precursor composition suitable, upon dispersing, dilution or suspension in an aqueous medium, for simulating fed-state gastric fluids of mammalian species, wherein said biorelevant precursor composition comprises a substantially solid/sol-id-like concentrate, a viscous gel-like concentrate, or a liquid fat dispersion/concentrate, comprising at least one primary component selected from each of the following groups of primary components comprising: i) Triglyceride and/or diglyceride and/or monoglyceride or any combinations thereof in an amount of from 1-70% by weight; ii) Lecithin and/or lysolecithin in an amount of from 1-45% by weight; iii) Carbohydrate in an amount of from 15-70% by weight; and iv) Water or other aqueous medium in an amount of from 1-70% by weight; wherein the weight ratio of total fats (one or more primary components from each of groups i) and ii) combined): total carbohydrates (one or more primary components from group iii) combined) is between 20:1 to 1:20; and the weight raType: ApplicationFiled: April 6, 2020Publication date: June 9, 2022Inventors: MATHEW LOUIS STEVEN LEIGH, VASCO RAFAEL FERNANDES DOS SANTOS, STEVEN LEIGH
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Publication number: 20210255073Abstract: A method for preparing a buffer solution suitable for physiologically relevant in vitro drug dissolution testing, drug solubility testing and/or drug profiling, the method comprising: (a) dispensing from a deformable container into a second container a predetermined quantity of a concentrate of the buffer solution, said deformable container having an orifice or aperture configured to dispense the concentrate in a dropwise manner and/or in a controlled stream, and (b) diluting the predetermined quantity of the concentrate with a predetermined quantity of a solvent to produce the buffer solution. A pack comprising a container and a concentrate of said buffer solution within the container, and a method for preparing the said pack, are also provided.Type: ApplicationFiled: June 12, 2019Publication date: August 19, 2021Inventors: MATHEW LOUIS STEVEN LEIGH, VASCO RAFAEL FERNANDES DOS SANTOS, DARYL LOUIS VAN LEIGH, ORFHLAITH TESS MCCULLOUGH, STEVEN LEIGH
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Publication number: 20160299113Abstract: There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.Type: ApplicationFiled: November 18, 2014Publication date: October 13, 2016Inventors: Steve Leigh, Mathew Louis Steven Leigh, Peter Van Hoogevest, Daniel Streich, Jacques Quinton
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Publication number: 20150064794Abstract: This application relates to a homogeneous biorelevant composition for preparing fasted state biorelevant media having a surface tension between 25 mN/m and 50 mN/m for simulating fasted state gastric and fasted state upper small intestinal fluids of mammalian species, especially humans, dogs, etc. comprising at least one bile salt, eg. sodium taurocholate or sodium taurodeoxycholate; at least one phospholipid, especially 60-99 wt % phosphatidylcholine (PC), enzyme digested diacylphospholipids containing 50-90 wt % of monoacyl-PC; or mixtures thereof; and at least one fatty acid or monovalent salt of the fatty acid, such as sodium oleate. The application also relates to an aqueous biorelevant media composed of surfactants occurring in the gastrointestinal tract of mammals, in particular when prepared from above homogeneous biorelevant composition.Type: ApplicationFiled: April 2, 2013Publication date: March 5, 2015Inventors: Mathew Louis Steven Leigh, Steve Leigh, Jennifer Dressman, Bastian Kloefer, Marcel Arndt, Alexander Fuchs
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Patent number: 8889189Abstract: There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.Type: GrantFiled: October 16, 2012Date of Patent: November 18, 2014Assignee: Phares Pharmaceutical Research, N.V.Inventors: Steve Leigh, Mathew Louis Steven Leigh, Peter Van Hoogevest, Daniel Streich, Jacques Quinton
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Patent number: 8632832Abstract: The present disclosure describes a method for the continuous dissolution of e.g. crystalline astaxanthin or canthaxanthin suspension in oil, by applying heat for a predetermined period using an in-line or optionally batch wise-process, followed by cooling the heated solution with an oil phase or heat exchanger. The resulting oil solution may be used as such or added directly to feed components which are turned into feed compositions by extrusion, compaction or granulation. Alternatively the oil solution is spray coated or directly loaded to extruded or compacted pellets and granulates. The disclosure avoids using formulated carotenoids prepared by known multi-step production methods requiring solvents, solvent removal, cooling and emulsification with an aqueous phase or precipitation and recovery steps.Type: GrantFiled: November 21, 2007Date of Patent: January 21, 2014Assignee: Phares Pharmaceutical Research N.V.Inventors: Steve Leigh, Mathew Louis Steven Leigh, Peter Van Hoogevest
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Patent number: 8287907Abstract: There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.Type: GrantFiled: November 10, 2006Date of Patent: October 16, 2012Assignee: Phares Pharmaceutical Research, N.V.Inventors: Steve Leigh, Matthew Louis Steven Leigh, Peter Van Hoogevest, Daniel Streich, Jacques Quinton
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Publication number: 20110244028Abstract: The invention describes a method of preparing lipid compositions by associating pH sensitive compounds which maybe weak acids, bases or amphoteric compounds with at least one ionisable or pH sensitive group and low water solubility into preformed and standardised lipid particles by pH manipulation. Drug association is carried out in situ by changing the pH of the aqueous medium to pH 6-8 wherein the compound spontaneously partitions into the lipid particles. Drug association may also be carried out by exploiting pH changes in the GI tract. The lipophilic compound is solubilised by the lipid particles and may be used as such for in-vitro and pharmacokinetic assessments or processed for oral, parenteral or topical therapy.Type: ApplicationFiled: September 28, 2009Publication date: October 6, 2011Inventors: Steve Leigh, Mathew Leuis Steven Leigh, Peter Van Hoogevest
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Patent number: 7563935Abstract: Mixtures of specific crystal forms of astaxanthin and the individual crystal forms designated crystal Form I and II and disclosed together with methods for preparing said crystal Forms. Methods for preparing nutritional dosage forms including the disclosed astaxanthin crystal forms for the life science industry are also disclosed.Type: GrantFiled: February 15, 2008Date of Patent: July 21, 2009Assignee: Phares Pharmaceutical Research N.V. et al.Inventors: Steve Leigh, Mathew Louis Steven Leigh, Peter Van Hoogevest
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Publication number: 20090145248Abstract: There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.Type: ApplicationFiled: November 10, 2006Publication date: June 11, 2009Applicant: PHARES PHARMACEUTICAL RESEARCH N.V.Inventors: Steve Leigh, Matthew Louis Steven Leigh, Peter Van Hoogevest, Daniel Streich, Jacques Quinton
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Publication number: 20080311267Abstract: The present disclosure describes a method for the continuous dissolution of e.g. crystalline astaxanthin or canthaxanthin suspension in oil, by applying heat for a predetermined period using an in-line or optionally batch wise-process, followed by cooling the heated solution with an oil phase or heat exchanger. The resulting oil solution may be used as such or added directly to feed components which are turned into feed compositions by extrusion, compaction or granulation. Alternatively the oil solution is spray coated or directly loaded to extruded or compacted pellets and granulates. The disclosure avoids using formulated carotenoids prepared by known multi-step production methods requiring solvents, solvent removal, cooling and emulsification with an aqueous phase or precipitation and recovery steps.Type: ApplicationFiled: November 21, 2007Publication date: December 18, 2008Applicant: PHARES PHARMACEUTICAL RESEARCHInventors: Steve Leigh, Mathew Louis Steven Leigh, Peter Van Hoogevest
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Publication number: 20080234521Abstract: Mixtures of specific crystal forms of astaxanthin and the individual crystal forms designated crystal Form I and II and disclosed together with methods for preparing said crystal Forms. Methods for preparing nutritional dosage forms including the disclosed astaxanthin crystal forms for the life science industry are also disclosed.Type: ApplicationFiled: February 15, 2008Publication date: September 25, 2008Applicant: PHARES PHARMACEUTICAL RESEARCH N. V.Inventors: Steve LEIGH, Mathew Louis Steven Leigh, Peter Van Hoogevest
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Publication number: 20080131499Abstract: Compositions for forming molecular associates with lipophilic compounds and an improved method of loading lipophilic biologically active compounds into previously formed, aqueous suspensions of lipid particles. A preferred embodiment for injection purposes comprise lipid particles having sizes below 1000 nm in diameter, in a vial or other suitable container are described. The method involves mixing a lipophilic compound either in solution or as an amorphous, preferably lyophilised powder in a first container with an aqueous suspension of lipid particles contained in a second container to form molecular associates. Only minimum agitation is required. The entire procedure may be carried out instantly in situ, in sealed sterile units just prior to use in the hospital ward or by the bedside.Type: ApplicationFiled: January 2, 2008Publication date: June 5, 2008Applicant: PHARES PHARMACEUTICAL RESEARCH N.V.Inventors: Steven Leigh, Mathew Louis Steven Leigh, Peter Van Hoogevest, Henricus Tiemessen
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Patent number: 6960354Abstract: A composition in the form of a dry powder and which comprises: a) at least one membrane lipid, and b) at least one biologically active compound comprising a xanthine and/or a carboxylic acid, and which forms structured lipid assemblies when dispersed/dissolved in an aqueous medium. A method of preparing such a composition is also provided, together with a dispersion of structured lipid assemblies suspended in a solution of at least one biologically active compound and a method of preparing the same. The compositions and dispersions are suitable for use in creams and lotions for skin care.Type: GrantFiled: February 2, 2000Date of Patent: November 1, 2005Assignee: Phares Technology BVInventors: Steven Leigh, Caroline Mary Thompson, Mathew Louis Steven Leigh
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Patent number: D615792Type: GrantFiled: January 21, 2009Date of Patent: May 18, 2010Inventor: Steven Leigh
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Patent number: D1024063Type: GrantFiled: November 2, 2021Date of Patent: April 23, 2024Assignee: LOGITECH EUROPE S.A.Inventors: James Leigh Toggweiler, Steven Ryutaro Takayama, Anthony Cooper Mattana, Matthew Fumio Yamamoto, Adam Kirk Bennett, Aron Michael Rosenberg