Patents by Inventor Steven M. Wenglowsky

Steven M. Wenglowsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Raf inhibitor compounds and methods of use thereof
    Patent number: 8338452
    Abstract: Compounds of Formula (I) are useful for inhibition of Raf kinases. Methods of using compounds of Formula (I) and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: December 25, 2012
    Assignees: Array BioPharma Inc., Genentech, Inc.
    Inventors: Kateri A. Ahrendt, Alexandre J. Buckmelter, Jonas Grina, Joshua D. Hansen, Ellen R. Laird, David Moreno, Brad Newhouse, Li Ren, Steven M. Wenglowsky, Bainian Feng, Janet Gunzner, Kim Malesky, Simon Mathieu, Joachim Rudolph, Zhaoyang Wen, Wendy B. Young
  • RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20110110889
    Abstract: Compounds of Formula (I) are useful for inhibition of Raf kinases. Methods of using compounds of Formula (I) and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
    Type: Application
    Filed: February 27, 2009
    Publication date: May 12, 2011
    Applicants: Array Bio Pharma Inc., Grenentech ,Inc.
    Inventors: Kateri A. Ahrendt et al., Alexander J. Buckmelter, Jonas Grina, Joshua D. Hansen, Ellen R. Laird, David Moreno, Brad Newhouse, Li Ren, Steven M. Wenglowsky, Bainian Feng, Janet Gunzner, Kim Malesky, Simon Mathieu, Joachim Rudolph, Zhaoyang Wen, Wendy B. Young
  • PYRAZOLE [3, 4-B] PYRIDINE RAF INHIBITORS
    Publication number: 20110092479
    Abstract: Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
    Type: Application
    Filed: February 27, 2009
    Publication date: April 21, 2011
    Applicants: Array BioPharma Inc., Genentech, Inc.
    Inventors: Kateri A. Ahrendt, Alexandre J. Buckmelter, Jason De Meese, Jonas Grina, Joshua D. Hansen, Ellen R. Laird, Paul Lunghofer, David Moreno, Brad Newhouse, Li Ren, Jeongbeob Seo, Hongqi Tian, Steven M. Wenglowsky, Bainian Feng, Janet Gunzner, Kim Malesky, Simon Mathieu, Joachim Rudolph, Zhaoyang Wen, Wendy B. Young
  • MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION
    Publication number: 20090286843
    Abstract: The embodiments provide compounds of the general formulas I-XIX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
    Type: Application
    Filed: October 20, 2008
    Publication date: November 19, 2009
    Inventors: LAWRENCE M. BLATT, STEVEN W. ANDREWS, KEVIN R. CONDROSKI, GEORGE A. DOHERTY, YUTONG JIANG, JOHN A. JOSEY, APRIL L. KENNEDY, MACHENDER R. MADDURU, PETER J. STENGEL, STEVEN M. WENGLOWSKY, BENJAMIN T. WOODARD, LAURA WOODARD
  • MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION
    Publication number: 20090111982
    Abstract: The embodiments provide compounds of the general formulas I-XIX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
    Type: Application
    Filed: December 22, 2008
    Publication date: April 30, 2009
    Inventors: Lawrence M. Blatt, Steven W. Andrews, Kevin R. Condroski, George A. Doherty, Yutong Jiang, John A. Josey, April L. Kennedy, Machender R. Madduru, Peter J. Stengel, Steven M. Wenglowsky, Benjamin T. Woodard, Laura Woodard
  • MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION
    Publication number: 20090111969
    Abstract: The embodiments provide compounds of the general formulas I-XIX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
    Type: Application
    Filed: December 22, 2008
    Publication date: April 30, 2009
    Inventors: Lawrence M. Blatt, Steven W. Andrews, Kevin R. Condroski, George A. Doherty, Yutong Jiang, John A. Josey, April L. Kennedy, Machender R. Madduru, Peter J. Stengel, Steven M. Wenglowsky, Benjamin T. Woodard, Laura Woodard
  • MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION
    Publication number: 20090105471
    Abstract: The embodiments provide compounds of the general formulas I-XIX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
    Type: Application
    Filed: December 22, 2008
    Publication date: April 23, 2009
    Inventors: Lawrence M. Blatt, Steven W. Andrews, Kevin R. Condroski, George A. Doherty, Yutong Jiang, John A. Josey, April L. Kennedy, Machender R. Madduru, Peter J. Stengel, Steven M. Wenglowsky, Benjamin T. Woodard, Laura Woodard
  • Macrocyclic compounds as inhibitors of viral replication
    Patent number: 7491794
    Abstract: The embodiments provide compounds of the general formulas I-XIX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: February 17, 2009
    Assignee: Intermune, Inc.
    Inventors: Lawrence M. Blatt, Steven W. Andrews, Kevin R. Condroski, Yutong Jiang, April L. Kennedy, Peter J. Stengel, Steven M. Wenglowsky