Abstract: A method, device, and system for modifying or destroying selected tissue, by selecting an area of tissue for treatment, collecting the area between a plurality of energy transmitting elements, applying an electric current and/or electromagnetic radiation between the energy transmitting elements, and applying the electric current and/or electromagnetic radiation until, for example, the cells are modified or destroyed. Cooling may be applied to prevent unwanted modification. Conducting mediums may be applied to control tissue modification. Embodiments of the present invention may be used for treatment of fat cells, acne, lesions, tattoo removals etc.