Patents by Inventor Steven Rowe
Steven Rowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11938201Abstract: Imaging and radiotherapeutics agents targeting fibroblast-activation protein-? (FAP-?) and their use in imaging and treating FAP-? related diseases and disorders are disclosed.Type: GrantFiled: July 18, 2023Date of Patent: March 26, 2024Assignee: The Johns Hopkins UniversityInventors: Xing Yang, Sridhar Nimmagadda, Steven Rowe, Stephanie Slania, Martin G. Pomper
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Publication number: 20240082027Abstract: A distal aortic stent graft assembly including a main body having a proximal end and a distal end. The main body defines a peripheral opening. The proximal end defines a proximal opening. The distal end defines a distal opening. The proximal opening and the distal opening are configured to perfuse blood through the main body when the main body is in a deployed state. The distal aortic stent graft assembly further includes a coupling extending radially from the main body and corresponding to the opening in the main body. The coupling is configured to align with a blood vessel and perfuse blood through the coupling when the coupling is in the deployed state.Type: ApplicationFiled: November 21, 2023Publication date: March 14, 2024Inventors: Keith PERKINS, Zachary BORGLIN, Mark STIGER, Julie BENTON, Steven CLAESSENS, Travis ROWE, Mark YOUNG
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Patent number: 11914395Abstract: Autonomous vehicles are capable of executing missions that abide by on-street rules or regulations, while also being able to seamlessly transition to and from “zones,” including off-street zones, with their our set(s) of rules or regulations. An on-board memory stores roadgraph information. An on-board computer is operative to execute commanded driving missions using the roadgraph information, including missions with one or more zones, each zone being defined by a sub-roadgraph with its own set of zone-specific driving rules and parameters. A mission may be coordinated with one or more payload operations, including zone with “free drive paths” as in a warehouse facility with loading and unloading zones to pick up payloads and place them down, or zone staging or entry points to one or more points of payload acquisition or placement. The vehicle may be a warehousing vehicle such as a forklift.Type: GrantFiled: June 26, 2022Date of Patent: February 27, 2024Assignee: Cybernet Systems Corp.Inventors: Glenn Beach, Douglas Haanpaa, Charles J. Jacobus, Steven Rowe
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Publication number: 20230416231Abstract: The present disclosure is concerned with substituted uracil compounds, pharmaceutical compositions comprising the compounds, and methods of treating disorders associated with the presence of a premature termination codon such as, for example, cystic fibrosis, Duchenne muscular dystrophy, aniridia, Becker muscular dystrophy, spinal muscular atrophy, Hurler syndrome, hemophilia, epidermolysis bullosa (e.g., dystrophic (DEB) form, junctional (JEB) form), Usher syndrome, and cancer, using the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: February 27, 2023Publication date: December 28, 2023Inventors: Kevin Jay Rodzinak, Terry Smalley, Robert Hunter, John P. Tillotson, Corinne E. Augelli-Szafran, Bini Mathew, David Bedwell, Steven Rowe
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Publication number: 20230364274Abstract: Imaging and radiotherapeutics agents targeting fibroblast-activation protein-? (FAP-?) and their use in imaging and treating FAP-? related diseases and disorders are disclosed.Type: ApplicationFiled: July 18, 2023Publication date: November 16, 2023Inventors: Xing Yang, Sridhar Nimmagadda, Steven Rowe, Stephanie Slania, Martin G. Pomper
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Publication number: 20220326717Abstract: Autonomous vehicles are capable of executing missions that abide by on-street rules or regulations, while also being able to seamlessly transition to and from “zones,” including off-street zones, with their our set(s) of rules or regulations. An on-board memory stores roadgraph information. An on-board computer is operative to execute commanded driving missions using the roadgraph information, including missions with one or more zones, each zone being defined by a sub-roadgraph with its own set of zone-specific driving rules and parameters. A mission may be coordinated with one or more payload operations, including zone with “free drive paths” as in a warehouse facility with loading and unloading zones to pick up payloads and place them down, or zone staging or entry points to one or more points of payload acquisition or placement. The vehicle may be a warehousing vehicle such as a forklift.Type: ApplicationFiled: June 26, 2022Publication date: October 13, 2022Applicant: Cybernet Systems Corp.Inventors: Glenn Beach, Douglas Haanpaa, Charles J. Jacobus, Steven Rowe
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Patent number: 11372425Abstract: Autonomous vehicles are capable of executing missions that abide by on-street rules or regulations, while also being able to seamlessly transition to and from “zones,” including off-street zones, with their our set(s) of rules or regulations. An on-board memory stores roadgraph information. An on-board computer is operative to execute commanded driving missions using the roadgraph information, including missions with one or more zones, each zone being defined by a sub-roadgraph with its own set of zone-specific driving rules and parameters. A mission may be coordinated with one or more payload operations, including zone with “free drive paths” as in a warehouse facility with loading and unloading zones to pick up payloads and place them down, or zone staging or entry points to one or more points of payload acquisition or placement. The vehicle may be a warehousing vehicle such as a forklift.Type: GrantFiled: October 10, 2019Date of Patent: June 28, 2022Assignee: Cybernet Systems Corp.Inventors: Glenn Beach, Douglas Haanpaa, Charles J. Jacobus, Steven Rowe
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Patent number: 10960018Abstract: The present disclosure provides compositions and methods for treating and/preventing diseases and conditions associated with premature termination mutations. The methods disclosed herein comprise the step of administering to the subject a therapeutically effective dose of a compound described herein that induces read-through of the premature termination codon. The methods of the present disclosure may further comprise treating the subject with enzyme replacement therapy wherein the enzyme replacement therapy is selected for the disease or condition to be treated. Furthermore, the present disclosure provides method of pharmacologically suppressing premature termination codons in a subject in need of such suppression.Type: GrantFiled: April 17, 2017Date of Patent: March 30, 2021Assignee: The UAB Research FoundationInventors: Steven Rowe, David M. Bedwell, Venkateshwar Mutyam, Ming Du, Kim M. Keeling
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Patent number: 10857246Abstract: Highly potent and selective radionuclide-based imaging and therapy agents targeting carbonic anhydrase IX with minimum non-specific organ uptake are disclosed. Methods of imaging and/or treating carbonic anhydrase IX-expressing cells or tumors also are disclosed.Type: GrantFiled: June 1, 2016Date of Patent: December 8, 2020Assignee: The Johns Hopkins UniversityInventors: Xing Yang, Il Minn, Steven Rowe, Sangeeta Ray, Ronnie C. Mease, Michael Gorin, Mohamad Allaf, Martin G. Pomper
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Publication number: 20200330624Abstract: Imaging and radiotherapeutics agents targeting fibroblast-activation protein-? (FAP-?) and their use in imaging and treating FAP-? related diseases and disorders are disclosed.Type: ApplicationFiled: October 23, 2018Publication date: October 22, 2020Inventors: Xing Yang, Sridhar Nimmagadda, Steven Rowe, Stephanie Slania, Martin G. Pomper
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Publication number: 20200057452Abstract: Autonomous vehicles are capable of executing missions that abide by on-street rules or regulations, while also being able to seamlessly transition to and from “zones,” including off-street zones, with their our set(s) of rules or regulations. An on-board memory stores roadgraph information. An on-board computer is operative to execute commanded driving missions using the roadgraph information, including missions with one or more zones, each zone being defined by a sub-roadgraph with its own set of zone-specific driving rules and parameters. A mission may be coordinated with one or more payload operations, including zone with “free drive paths” as in a warehouse facility with loading and unloading zones to pick up payloads and place them down, or zone staging or entry points to one or more points of payload acquisition or placement. The vehicle may be a warehousing vehicle such as a forklift.Type: ApplicationFiled: October 10, 2019Publication date: February 20, 2020Applicant: Cybernet Systems Corp.Inventors: Glenn Beach, Douglas Haanpaa, Charles J. Jacobus, Steven Rowe
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Patent number: 10459453Abstract: Autonomous vehicles are capable of executing missions that abide by on-street rules or regulations, while also being able to seamlessly transition to and from “zones,” including off-street zones, with their our set(s) of rules or regulations. An on-board memory stores roadgraph information. An on-board computer is operative to execute commanded driving missions using the roadgraph information, including missions with one or more zones, each zone being defined by a sub-roadgraph with its own set of zone-specific driving rules and parameters. A mission may be coordinated with one or more payload operations, including zone with “free drive paths” as in a warehouse facility with loading and unloading zones to pick up payloads and place them down, or zone staging or entry points to one or more points of payload acquisition or placement. The vehicle may be a warehousing vehicle such as a forklift.Type: GrantFiled: November 8, 2017Date of Patent: October 29, 2019Inventors: Glenn Beach, Douglas Haanpaa, Charles J. Jacobus, Steven Rowe
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Publication number: 20190192699Abstract: Highly potent and selective radionuclide-based imaging and therapy agents targeting carbonic anhydrase IX with minimum non-specific organ uptake are disclosed. Methods of imaging and/or treating carbonic anhydrase IX-expressing cells or tumors also are disclosed.Type: ApplicationFiled: May 12, 2017Publication date: June 27, 2019Inventors: Xing YANG, Il MINN, Steven ROWE, Sangeeta RAY, Ronnie C. MEASE, Michael GORIN, Mohamad ALLAF, Martin G. POMPER
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Publication number: 20190125775Abstract: The present disclosure provides compositions and methods for treating and/preventing diseases and conditions associated with premature termination mutations. The methods disclosed herein comprise the step of administering to the subject a therapeutically effective dose of a compound described herein that induces read-through of the premature termination codon. The methods of the present disclosure may further comprise treating the subject with enzyme replacement therapy wherein the enzyme replacement therapy is selected for the disease or condition to be treated. Furthermore, the present disclosure provides method of pharmacologically suppressing premature termination codons in a subject in need of such suppression.Type: ApplicationFiled: April 17, 2017Publication date: May 2, 2019Inventors: Steven ROWE, David M. BEDWELL, Venkateshwar MUTYAM, Ming DU, Kim M. KEELING
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Publication number: 20180133348Abstract: Highly potent and selective radionuclide-based imaging and therapy agents targeting carbonic anhydrase IX with minimum non-specific organ uptake are disclosed. Methods of imaging and/or treating carbonic anhydrase IX-expressing cells or tumors also are disclosed.Type: ApplicationFiled: June 1, 2016Publication date: May 17, 2018Inventors: XING YANG, IL MINN, STEVEN ROWE, SANGEETA RAY, RONNIE C. MEASE, MICHAEL GORIN, MOHAMAD ALLAF, MARTIN G. POMPER
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Publication number: 20180129220Abstract: Autonomous vehicles are capable of executing missions that abide by on-street rules or regulations, while also being able to seamlessly transition to and from “zones,” including off-street zones, with their our set(s) of rules or regulations. An on-board memory stores roadgraph information. An on-board computer is operative to execute commanded driving missions using the roadgraph information, including missions with one or more zones, each zone being defined by a sub-roadgraph with its own set of zone-specific driving rules and parameters. A mission may be coordinated with one or more payload operations, including zone with “free drive paths” as in a warehouse facility with loading and unloading zones to pick up payloads and place them down, or zone staging or entry points to one or more points of payload acquisition or placement. The vehicle may be a warehousing vehicle such as a forklift.Type: ApplicationFiled: November 8, 2017Publication date: May 10, 2018Inventors: Glenn Beach, Douglas Haanpaa, Charles J. Jacobus, Steven Rowe
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Publication number: 20050002837Abstract: A new reactor apparatus that can be used to carry out chemical reactions in a fluidized catalyst bed at high temperatures with reduced afterburning or other undesirable downstream side reactions.Type: ApplicationFiled: May 7, 2004Publication date: January 6, 2005Inventors: Louis Trott, David Wagner, Steven Rowe, Robert Gustaferro, Gregory Norenberg, Kenneth Keckler, Robert Hepfer
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Patent number: 6559833Abstract: A touchpad and supporting logic that provides absolute or relative positioning of a graphics cursor on a display. Absolute positioning is preferably invoked by touching the touchpad in a designated region. Relative positioning is preferably implemented by continual movement across a touchpad relative to a reference location. A method of achieving absolute and relative positioning is also disclosed.Type: GrantFiled: October 1, 1998Date of Patent: May 6, 2003Assignee: Hewlett-Packard Development CompanyInventor: Mark Steven Rowe
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Publication number: 20030048259Abstract: A touchpad and supporting logic that provides absolute or relative positioning of a graphics cursor on a display. Absolute positioning is preferably invoked by touching the touchpad in a designated region. Relative positioning is preferably implemented by continual movement across a touchpad relative to a reference location. A method of achieving absolute and relative positioning is also disclosed.Type: ApplicationFiled: October 1, 1998Publication date: March 13, 2003Inventor: MARK STEVEN ROWE
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Patent number: 5403311Abstract: A catheter includes a flexible elongated catheter body that defines a needle-receiving, or probe-receiving, lumen, a retractable tissue-penetrable needle, or probe, and an electrode mounted on the distal portion of the catheter body. The needle provides a fluid passage for introducing fluid into tissue to permit the introduction of sclerotic agents for enhancing electrocoagulation of the tissue, heat-responsive drugs for improving the bonding to tissue surfaces, or vaso-constrictor drugs. The probe can also have a passage for fluid. The electrode can provide bipolar electro-coagulation of tissue in combination with an additional electrode mounted on the catheter body, or alternatively, the electrode can be employed in combination with either the needle or probe to establish a bipolar electro-coagulation path through tissue. The needle, or probe, in combination with an external electrode can be used to provide unipolar electro-coagulation, or ablation.Type: GrantFiled: March 29, 1993Date of Patent: April 4, 1995Assignee: Boston Scientific CorporationInventors: John E. Abele, Steven Rowe, Christopher A. Rowland, Michael G. Vergano