Abstract: A container device with an outer shell that has an opening that is sealed by a closure mechanism. The closure mechanism may include resealable closure elements that are configured to partially or wholly seal the opening. In some examples, the closure elements may be magnetic strips. In addition, the closure mechanism may include curved members to prevent the opening from closing when the closure mechanism is in an open configuration.

Abstract: A wearable medical monitoring (WMM) system may be worn for a long time. Some embodiments of WMM systems are wearable cardioverter defibrillator (WCD) systems. In such systems, ECG electrodes sense an ECG signal of the patient, and store it over the long-term. The stored ECG signal can be analyzed for helping long-term heart rate monitoring of the patient. The heart rate monitoring can be assisted a) by special filtering techniques that remove short-term variations inherent in patients' short-term heart rate determinations, and b) by indication techniques that indicate when conditions hampered sensing of the ECG signal too much for a reliable heart rate determination.

Abstract: An insulating container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching devices, in the closed configuration. In some examples, the insulating container further includes a pull handle assembly with a telescopic three-stage arm configuration defined by a stowed configuration, a partially extended configuration, and a fully extended configuration. In other examples, the insulating container further includes a wheel assembly with a pair of wheels mounted with one or two axles, and further including a wheel grommet for absorbing shock and cushioning the axle. In still other examples, the insulating container further includes a drain plug assembly on the rear sidewall adjacent to the bottom portion of the base, the drain plug assembly comprising a main tube that cooperatively engages with an outer tube with a plurality of ratchet teeth that engage one or more ratchet keys on the main tube.

Abstract: A closure having a first flange with first engagement mechanism and a second with a second engagement mechanism disposed between the first end and the second end. The first engagement mechanism configured to engage the second engagement mechanism. A slider configured to selectively engage the first engagement mechanism and the second mechanism when moved in a first direction and disengage the first engagement mechanism from the second engagement mechanism when moved in a second direction. The closure is substantially watertight in the closed position.

Abstract: Disclosed herein are platforms, systems, and methods including a cell culture system that includes a cell culture container comprising a cell culture, the cell culture receiving input cells, a cell imaging subsystem configured to acquire images of the cell culture, a computing subsystem configured to perform a cell culture process on the cell culture according to the images acquired by the cell imaging subsystem, and a cell editing subsystem configured to edit the cell culture to produce output cell products according to the cell culture process.

Abstract: The invention relates to compounds of formula I wherein R1, R2 and - - - - - are as defined herein, pharmaceutical compositions comprising the compounds and methods of treating COVID-19 in a patient by administering therapeutically effective amounts of the compounds and methods of inhibiting or preventing replication of SARS-CoV-2 with the compounds.

Abstract: An example bag may include an outer shell comprising a front panel, a rear panel, a top sidewall, a bottom sidewall, a first sidewall, a second sidewall forming, and a closure configured to move from an open position to a closed position. The bag may also include a pair of adjustable straps. The adjustable straps can be configured to move from a first backpack carry position to a second hand carry position by releasing the adjustable straps from the outer shell of the bag from the first carry position and securing the adjustable straps to the second carry position.

Abstract: Disclosed herein are platforms, systems, and methods including a cell culture system that includes a cell culture container comprising a cell culture, the cell culture receiving input cells, a cell imaging subsystem configured to acquire images of the cell culture, a computing subsystem configured to perform a cell culture process on the cell culture according to the images acquired by the cell imaging subsystem, and a cell editing subsystem configured to edit the cell culture to produce output cell products according to the cell culture process.

Abstract: Disclosed are methods and apparatuses for mitigating the formation of concentrated wake vortex structures generated from lifting or thrust-generating bodies and maneuvering control surfaces wherein the use of contour surface geometries promotes vortex-mixing of high and low flow fluids. The methods and apparatuses can be combined with various drag reduction techniques, such as the use of riblets of various types and/or compliant surfaces (passive and active). Such combinations form unique structures for various fluid dynamic control applications to suppress transiently growing forms of boundary layer disturbances in a manner that significantly improves performance and has improved control dynamics.

Abstract: Disclosed are methods and apparatuses for mitigating the formation of concentrated wake vortex structures generated from lifting or thrust-generating bodies and maneuvering control surfaces wherein the use of contour surface geometries promotes vortex-mixing of high and low flow fluids. The methods and apparatuses can be combined with various drag reduction techniques, such as the use of riblets of various types and/or compliant surfaces (passive and active). Such combinations form unique structures for various fluid dynamic control applications to suppress transiently growing forms of boundary layer disturbances in a manner that significantly improves performance and has improved control dynamics.

Abstract: An apparatus for generating audio synchronized optical output is provided. The apparatus comprises an input channel to receive an input signal from an audio source and a controller. The controller is configured to receive the input signal from the input channel, analyze the input signal to determine one or more characteristics of the input signal. The apparatus associates the determined one or more characteristics of the input signal to one or more parameters of an optical output from an optical source and modulates the one or more parameters of the optical output in accordance with the one or more characteristics of the input signal. The system for generates real-time audio and/or performance synchronized optical outputs and enables connecting stage implements, musical instruments, lights, visual effects, lasers and other theatrical effects to be controllable by lighting data from human interactions with musical instruments or other stage or human interface devices.

Abstract: Techniques for genetic programming based compression determination are described herein. An aspect includes adding a first plurality of randomly generated compression algorithms to a first set of compression algorithms. Another aspect includes determining a respective mutated version of each of the first plurality of randomly generated compression algorithms. Another aspect includes adding the determined mutated versions to the first set of compression algorithms. Another aspect includes evaluating and ranking the first set of compression algorithms based on respective achieved degrees of compression.

Abstract: Disclosed are methods and apparatuses for mitigating the formation of concentrated wake vortex structures generated from lifting or thrust-generating bodies and maneuvering control surfaces wherein the use of contour surface geometries promotes vortex-mixing of high and low flow fluids. The methods and apparatuses can be combined with various drag reduction techniques, such as the use of riblets of various types and/or compliant surfaces (passive and active). Such combinations form unique structures for various fluid dynamic control applications to suppress transiently growing forms of boundary layer disturbances in a manner that significantly improves performance and has improved control dynamics.

Abstract: This patent provides for a method and apparatus for mitigating the formation of concentrated wake vortex structures generated from lifting or thrust-generating bodies and maneuvering control surfaces wherein the use of contour surface geometries promotes vortex-mixing of high and low flow fluids. The method and apparatus can be combined with various drag reduction techniques, such as the use of riblets of various types and/or compliant surfaces (passive and active). Such combinations form unique structures for various fluid dynamic control applications to suppress transiently growing forms of boundary layer disturbances in a manner that significantly improves performance and has improved control dynamics.

Abstract: A tube manufacturing system is provided that is capable of manufacturing tube structures that are on the nanoscale and larger. The system provides for control as to the structure and atomic makeup of the feed sheet material used and provides motive force to the sheet material being used to continuously advance the sheet material through the various system components. After the tube structures are formed, they may be used in providing a source material for manufacturing macroscopic objects thus increasing the level of performance and capabilities of such objects due to the engineered properties of the tube structures formed within this system and method of manufacturing. Processes for manufacturing of nanotubes are also disclosed, as are nanotubes manufactured by the processes and system of the invention.

Abstract: Aircraft landing gear comprised of a wheel hub motor/generator includes alternating rotors and stators mounted with respect to the wheel support and wheel. The invention in certain embodiments can provide motive force to the wheel when electrical power is applied, e.g. prior to touch-down, thus decreasing the difference in relative velocities of the tire radial velocity with that of the relative velocity of the runway and reducing the sliding friction wear of the tire. After touchdown the wheel hub motor/generator may be used as a generator thus applying a regenerative braking force and/or a motorized braking action to the wheel. The energy generated upon landing may be dissipated through a resistor and/or stored for later use in providing a source for motive power to the aircraft wheels for taxiing and ground maneuvers of the aircraft. Methods and apparatuses for nose gear steering and ABS braking using the disclosed invention are described.

Abstract: Aircraft landing gear comprised of a wheel hub motor/generator includes alternating rotors and stators mounted with respect to the wheel support and wheel. The invention in certain embodiments can provide motive force to the wheel when electrical power is applied, e.g. prior to touch-down, thus decreasing the difference in relative velocities of the tire radial velocity with that of the relative velocity of the runway and reducing the sliding friction wear of the tire. After touchdown the wheel hub motor/generator may be used as a generator thus applying a regenerative braking force and/or a motorized braking action to the wheel. The energy generated upon landing may be dissipated through a resistor and/or stored for later use in providing a source for motive power to the aircraft wheels for taxiing and ground maneuvers of the aircraft. Methods and apparatuses for nose gear steering and ABS braking using the disclosed invention are described.