Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: A wearable computing device includes a housing having a wrist-side face configured to sit against a wrist of a user of the wearable computing device when being worn by the user, an electronic display arranged within the housing, a plurality of biometric sensor electrodes positioned on the wrist-side face so as to maintain skin contact with the user when being worn on the wrist by the user, and at least one driver communicatively coupled to the plurality of biometric sensor electrodes. Each of the plurality of biometric sensor electrodes continuously measures, at least, one or more parameters indicative of electrical impedance of the user at a location of the skin contact.

Abstract: Various embodiments of methods and systems for dynamically adjusting operating frequency settings of one or more processing components in a portable computing device (“PCD”) are disclosed. One such method involves receiving a request to adjust an operating frequency setting of a processing component to a required frequency (“F_req”) to process a workload. Factor readings associated with the operating capacity of the processing component may be taken. Based on the readings, performance curves associated with the processing component may be queried. The performance curves are used to determine the optimal operating frequency (“F_opt”) for the processing component. The F_opt is compared to the F_req and, if the F_req is less than F_opt, the operating frequency setting of the processing component is set to F_opt. Advantageously, as compared to F_req, at F_opt workload processing may be more efficient and a low power mode may be entered sooner.

Abstract: Various embodiments of methods and systems for dynamically adjusting operating frequency settings of one or more processing components in a portable computing device (“PCD”) are disclosed. One such method involves receiving a request to adjust an operating frequency setting of a processing component to a required frequency (“F_req”) to process a workload. Factor readings associated with the operating capacity of the processing component may be taken. Based on the readings, performance curves associated with the processing component may be queried. The performance curves are used to determine the optimal operating frequency (“F_opt”) for the processing component. The F_opt is compared to the F_req and, if the F_req is less than F_opt, the operating frequency setting of the processing component is set to F_opt. Advantageously, as compared to F_req, at F_opt workload processing may be more efficient and a low power mode may be entered sooner.

Abstract: Systems and methods for real-time control of a bus operating point in a portable computing device (“PCD”) are presented. An indication of an event occurring in a bus interface is used as an indicator of a mismatch between a resource request and a data throughput level that can be supported by the bus. A suitable mechanism for identifying the mismatch provides a cost effective and non-invasive solution that is generally applicable for all usage situations.

Abstract: An optical sensor assembly comprising a plurality of optical fibre sensor coils optically coupled by optical fibre; and an elongate support element, on which said plurality of optical fibre sensor coils and optically coupling optical fibre are mounted is disclosed. The support element has an elastic limit such that when said support element is bent from the elongate axis, the optical fibre fracture limit is reached before the elastic limit is reached. An array of these optical sensor assemblies, the mandrel on which the sensing coils are mounted and their method of manufacture are also disclosed.

Abstract: Primer casing (1) comprising sleeve portion (5) and leading portion (5a), wherein sleeve portion (5) includes tabs (6) to retain primer (11) and blasthole engagement means (2), and wherein leading portion (5a) comprises nose cone (8). Engagement means (2) comprises an array of rigid, multiple projections that are hinged and movable between a retracted position and a blasthole engagement position. Explosive loading hose (13) locales within hose receiving sleeve (7) and can be used to push primer casing (1) into the desired location within the blasthole prior to filling the blasthole with bulk explosive. Methods of loading a blasthole comprising inserting primer (11) into primer casing (1) and positioning primer casing (1) at a desired location in a blasthole are also described and claimed.