Abstract: A bolt installation and removal (BIR) system is used for assembling and disassembling a nuclear vessel. The BIR system includes a platform with a stand for supporting the nuclear vessel. A track extends around an outside perimeter of the platform and multiple tool carts include wheels that roll on the track. Tool towers are located on the carts and include tool assemblies configured to install and remove bolts on the nuclear reactor vessel. Magazine towers also extend up from the tool carts next to the tool towers and include magazines that hold bolts for exchanging with the tool assemblies. Drive mechanisms move tool heads in the tool assemblies around a first vertical axis, vertically up and down, and laterally to more simply and reliably install and remove the bolts in a radioactive underwater environment.

Abstract: A diffusion system to improve the efficiency, accuracy, and consistency of testing the release rate of an active ingredient in semisolid form through a membrane in between a dosage lid and a cell cap mounted on a cell in which a mixer is placed to mix the receptor medium in the cell as the semisolid diffuses through the membrane. The cell can be placed in a heating system to heat the samples. The cell has a sampling arm through which samples of the receptor medium can be extracted without opening the cell cap and dosage lid. The mixer may be cylindrical and may occupy a large surface area of the cell. The mixer may have grooves and other irregularities to increase turbulence while mixing. The system can be automated using an automated sampling and collection station.

Abstract: A diffusion system to improve the efficiency, accuracy, and consistency of testing the release rate of an active ingredient in semisolid form through a membrane in between a dosage lid and a cell cap mounted on a cell in which a mixer is placed to mix the receptor medium in the cell as the semisolid diffuses through the membrane. The cell can be placed in a heating system to heat the samples. The cell has a sampling arm through which samples of the receptor medium can be extracted without opening the cell cap and dosage lid. The mixer may be cylindrical and may occupy a large surface area of the cell. The mixer may have grooves and other irregularities to increase turbulence while mixing. The system can be automated using an automated sampling and collection station.

Abstract: A bolt installation and removal (BIR) system is used for assembling and disassembling a nuclear vessel. The BIR system includes a platform with a stand for supporting the nuclear vessel. A track extends around an outside perimeter of the platform and multiple tool carts include wheels that roll on the track. Tool towers are located on the carts and include tool assemblies configured to install and remove bolts on the nuclear reactor vessel. Magazine towers also extend up from the tool carts next to the tool towers and include magazines that hold bolts for exchanging with the tool assemblies. Drive mechanisms move tool heads in the tool assemblies around a first vertical axis, vertically up and down, and laterally to more simply and reliably install and remove the bolts in a radioactive underwater environment.

Abstract: A sensor is provided which is configured to detect the presence of multiple analytes, for example chemical or biological compounds, through the measurement of induced resonance shifts in a coupled array of microelectromechanical or micromechanical resonators.

Abstract: A sensor is provided which is configured to detect the presence of multiple analytes, for example chemical or biological compounds, through the measurement of induced resonance shifts in a coupled array of microelectromechanical or micromechanical resonators.

Abstract: A diffusion cell to facilitate the automatic or manual removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percantaneous absorption through a membrane of a substance from a donor chamber into a receptor chamber of the diffusion cell. There is utilized a capillary port through which the test aliquot is to be removed. A refilling tube connects also with the receptor chamber to add receptor liquid into the receptor chamber as the test aliquot is being removed. A quick release clamping apparatus secures the donor housing which contains the donor chamber tightly to the main housing of the diffusion cell.

Abstract: A diffusion cell to facilitate the automatic or manual removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percantaneous absorption through a membrane of a substance from a donor chamber into a receptor chamber of the diffusion cell. There is utilized a capillary port through which the test aliquot is to be removed. A refilling tube connects also with the receptor chamber to add receptor liquid into the receptor chamber as the test aliquot is being removed. A quick release clamping apparatus secures the donor housing which contains the donor chamber tightly to the main housing of the diffusion cell.

Abstract: A dissolution sampling apparatus which automatically extracts aliquots which contain a dissolved drug in solution from a plurality of dissolution containing flasks and tests each aliquot for the amount of drug dissolved within the aliquot. The sampling apparatus can resupply the removed aliquot. back to its source or the aliquot can be discarded as waste with new media being resupplied to the source. A syringe is used to remove the aliquots. A mechanically operated valve could be used with each syringe or a plurality of solenoids instead of the mechanically operated valve.

Abstract: A dynamic vibration absorber for a rotating machinery element preferably of the bifilar pendulum vibration absorber type wherein the absorber system includes one or more pair(s) of masses having identical paths of movement relative to the axis of the rotating element whose vibrations are being absorbed, the individual absorber masses of a given pair moving out-of-phase with respect to one another relative to the rotating element wherein a disturbance torque with a frequency that is a multiple of the rotation rate of the rotating element is absorbed by a one-half relative frequency motion of the corresponding half-order absorber pair. The half-order absorber pairs are driven primarily by centrifugal forces, move with a frequency one-half that of the disturbance torque and use non-linear Coriolis forces as the source of the counteracting torque.

Abstract: A diffusion cell to facilitate the automated removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percutaneous absorption through a membrane of a donor media from a donor chamber into the receptor chamber of the diffusion cell. There is utilized a sampling port through which the test aliquot is to be removed, the removal being achieved by means of a sample tube. Within the receptor chamber is located a stirring device in the form of a helical coil which is to be rotated to achieve stirring and homogeneous mixing of the liquid within the receptor chamber. Mounted within the coil is a filter screen to prevent particulate matter over a certain size from entering the sample tube and clogging such.

Abstract: A diffusion cell to facilitate the automated removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percutanous absorption through a membrane of a donor fluid from a donor chamber into the receptor chamber of the diffusion cell. There is utilized a sampling port through which the test aliquot is to be removed, the removal being achieved by means of a sample tube which is to be movable into and out of the receptor chamber. Within the receptor chamber is located a stirring device in the form of a helical coil which is to be rotated to achieve stirring and homogeneous mixing of the liquid within the receptor chamber. A refilling tube connects also with the receptor chamber to add liquid into the receptor chamber as the test aliquot has been removed. A leveling tube within the sampling port is to restore the initial preset receptor liquid volume between sampling intervals.