Patents by Inventor Stjepan Gamulin

Stjepan Gamulin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant of bacterium Clostridium histolyticum, a process for the obtaining thereof, and its use in the production of clostripain-free collagenase
    Patent number: 5252481
    Abstract: A mutant of bacterium Clostridium histolyticum, designated Clostridum histolyticum K26 clo 88 of the following characteristics: the lack of a motility system which is a fundamental characteristic of the parenteral strain; and, the inability to biosynthesize the accompanying enzyme clostripain. A process of obtaining the above mutant and its use in a process for the production of clostripain-free collagenase are also provided.
    Type: Grant
    Filed: July 23, 1991
    Date of Patent: October 12, 1993
    Assignee: Pliva Farmaceutska, Kemijska
    Inventors: Milan Holjevac, Ivan Udovicic, Sonja Cizmek, Vlasta Sojak-Derkos, Stjepan Gamulin, Vladimir Delic