Patents by Inventor Suying Liu
Suying Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240018131Abstract: Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.Type: ApplicationFiled: July 6, 2023Publication date: January 18, 2024Inventors: Wenjin Yang, Kai-Wei Chang, Suying Liu, Cheng-Han Tsai
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Patent number: 11739080Abstract: Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.Type: GrantFiled: May 14, 2019Date of Patent: August 29, 2023Assignee: Foresee Pharmaceuticals USA, Inc.Inventors: Wenjin Yang, Kai-Wei Chang, Suying Liu, Cheng-Han Tsai
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Patent number: 11365224Abstract: Three-dimensional, living, self-regenerative structures of predetermined geometry comprising solidified print material comprising a biofilm of Bacillus subtilis comprise a TasA-R protein, wherein R is a recombinant, heterologous functional group, wherein the TasA-R provides a preferably tunable physiochemical property like viscosity, reactivity, affinity as a function of the R group.Type: GrantFiled: February 7, 2021Date of Patent: June 21, 2022Assignee: ShanghaiTech UniversityInventors: Chao Zhong, Jiaofang Huang, Suying Liu, Chen Zhang
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Publication number: 20210214340Abstract: Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.Type: ApplicationFiled: May 14, 2019Publication date: July 15, 2021Inventors: Wenjin Yang, Kai-Wei CHANG, Suying LIU, Cheng-Han TSAI
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Publication number: 20210198325Abstract: Three-dimensional, living, self-regenerative structures of predetermined geometry comprising solidified print material comprising a biofilm of Bacillus subtilis comprise a TasA-R protein, wherein R is a recombinant, heterologous functional group, wherein the TasA-R provides a preferably tunable physiochemical property like viscosity, reactivity, affinity as a function of the R group.Type: ApplicationFiled: February 7, 2021Publication date: July 1, 2021Applicant: ShanghaiTech UniversityInventors: Chao Zhong, Jiaofang Huang, Suying Liu, Chen Zhang
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Patent number: 10851089Abstract: Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.Type: GrantFiled: May 14, 2019Date of Patent: December 1, 2020Assignee: Foresee Pharmaceuticals Co., Ltd.Inventors: Wenjin Yang, Kai-Wei Chang, Suying Liu, Cheng-Han Tsai
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Publication number: 20190352287Abstract: Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.Type: ApplicationFiled: May 14, 2019Publication date: November 21, 2019Inventors: Wenjin YANG, Kai-Wei CHANG, Suying LIU, Cheng-Han TSAI
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Publication number: 20190352288Abstract: Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acute lung injury, idiopathic pulmonary fibrosis (IPF), sarcoidosis, systemic sclerosis, liver fibrosis, nonalcoholic steatohepatitis (NASH), arthritis, cancer, heart disease, inflammatory bowel disease (IBD), acute kidney injury (AKI), chronic kidney disease (CKD), Alport syndrome, and nephritis.Type: ApplicationFiled: May 14, 2019Publication date: November 21, 2019Inventors: Wenjin YANG, Kai-Wei CHANG, Suying LIU, Cheng-Han TSAI
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Publication number: 20090291156Abstract: The present invention provides an herbal composition for improving aging skin, comprising extract of Panax ginseng, Acanthopanax and Carthamus tinctorius. The composition of present invention can further comprise extract of Lignum aquilariae and Resina boswelliae carterii. The present invention also provides a method for improving aging skin of a subject, comprising administrating a composition comprising extract of Panax ginseng, Acanthopanax and Carthamus tinctorius to the subject.Type: ApplicationFiled: May 20, 2008Publication date: November 26, 2009Applicant: SAGITTARIUS LIFE SCIENCE CORP.Inventor: Suying Liu
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Publication number: 20090186100Abstract: A composition comprising Semen Lactucae sativae, Fructus oryzae and Resina Boswelliae carterii for prophylaxis or treatment of skin-aging, increasing skin hydration, improving wrinkle; and facilitating wound healing rate and improving wound quality.Type: ApplicationFiled: January 22, 2008Publication date: July 23, 2009Applicant: SAGITTARIUS LIFE SCIENCE CORP.Inventors: Suying Liu, Pei-Fen Yang
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Publication number: 20090155395Abstract: The present invention provides a composition comprising Rehmanniae radix, Paeonia suffruticosa, Saposhnikovia divaricata, Schizonepeta multifida, Saphora flavescens, Paeonia lactiflora, Dictamnus dasycarpus, Mentha arvensis, Rheum palmatum, Xanthium sibiricum, Campsis grandiflora and Glycyrrhizae radix for treating or prophylaxis of acne and inflammation related to skin disorders.Type: ApplicationFiled: December 13, 2007Publication date: June 18, 2009Applicant: SAGITTARIUS LIFE SCIENCE CORP.Inventor: Suying Liu
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Patent number: 7459173Abstract: A pharmaceutical composition which can be used to prevent and treat bone fracture and osteoporosis. The composition is composed of Semen lactucae sativae 0.1-1, Lignum aquilariae resinatum 2-20, Fructus oryzae 1-5, Resina boswelliae carterii 0.1-1, Rhizoma atractylodis macrocephalae 0.1-1 and Semen cuscutae 0.1-1. The whole or the specific parts of the plants can be used to prepare the inventive pharmaceutical composition; preferred plants are Aquilariae lignum containing resin and Boswellia carterii containing resin. This pharmaceutical composition can be formulated into lozenge, tablet, film coated tablets, capsule, soft capsule, granule, powder, pill, solution, emulsion, injection solution, injection, ointment, cream, spray or inhalant.Type: GrantFiled: October 28, 2004Date of Patent: December 2, 2008Assignee: Sagittarius Life Science Corp.Inventors: Suying Liu, Yiming Tsal
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Patent number: 7134978Abstract: This invention is utilizing the principle of repulsion between oil and water, the differences of surface tension of oil and water, and the character of melting of gelatin materials in high temperature and solidification in cold temperature to produce a biodegradable seamless BB paintball for BB guns. It contains a colored edible oil solution and is safe when it hits the target to produce an obvious mark that is edible. The seamless paintballs so produced are consistent in size and weight. It reduces the possibility of jamming during shooting and loading of BB guns which are common complaints of the conventional BB paintballs. A specially designed double nozzled machine can produce oil-in-water perfectly round and seamless droplets. The oil solution contains the dyes and the water solution contains a specially formulated gelatin. The droplets are then solidified by a chilled cooling oil flow. The oil solution comprises of 1%–5% (W/W) edible dye in edible oil.Type: GrantFiled: July 28, 2003Date of Patent: November 14, 2006Assignee: Sagittarius Life Science CorporationInventors: Suying Liu, Ming Cherng Chou, Hui Ying Chen
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Publication number: 20060205546Abstract: Seamless BB paintballs are formed by utilizing the principle of repulsion between oil and water, the differences of surface tension of oil and water, and the character of melting of gelatin materials in high temperature and solidification in cold temperature to produce a biodegradable seamless paintball. The seamless paintballs contain a colored edible oil solution for improved safety for accidental ingestion and rupture on impact to improve safety relative to similarly-sized solid projectiles. The seamless paintballs may be produced at consistent sizes and weights, thereby reducing the possibility of jamming during shooting and/or unintended rupture during loading. The seamless paintballs may also be configured to improve storage stability and the trajectory consistency, thereby overcoming common limitations of conventional BB and paintball projectiles.Type: ApplicationFiled: February 21, 2006Publication date: September 14, 2006Inventors: Suying Liu, Ming Chou, Hui Chen
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Publication number: 20060093619Abstract: The present invention provides a pharmaceutical composition which can be used to prevent and treat bone fracture and osteoporosis. The composition is composed of Semen lactucae sativae 0.1-1, Lignum aquilariae resinatum 2-20, Fructus oryzae 1-5, Resina boswelliae carterii 0.1-1, Rhizoma atractylodis macrocephalae 0.1-1 and Semen cuscutae 0.1-1. The whole or the specific parts of the plants can be used to prepare the inventive pharmaceutical composition; preferred plants are Aquilariae lignum containing resin and Boswellia carterii containing resin. This pharmaceutical composition can be formulated into lozenge, tablet, film coated tablets, capsule, soft capsule, granule, powder, pill, solution, emulsion, injection solution, injection, ointment, cream, spray or inhalant.Type: ApplicationFiled: October 28, 2004Publication date: May 4, 2006Inventors: Suying Liu, Yiming Tsal
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Publication number: 20050025968Abstract: This invention is utilizing the principle of repulsion between oil and water, the differences of surface tension of oil and water, and the character of melting of gelatin materials in high temperature and solidification in cold temperature to produce a biodegradable seamless BB paintball for BB guns. It contains a colored edible oil solution and is safe when it hits the target to produce an obvious mark that is edible. The seamless paintballs so produced are consistent in size and weight. It reduces the possibility of jamming during shooting and loading of BB guns which are common complaints of the conventional BB paintballs. A specially designed double nozzled machine can produce oil-in-water perfectly round and seamless droplets. The oil solution contains the dyes and the water solution contains a specially formulated gelatin. The droplets are then solidified by a chilled cooling oil flow.The oil solution comprises of 1%-5% (W/W) edible dye in edible oil.Type: ApplicationFiled: July 28, 2003Publication date: February 3, 2005Inventors: Suying Liu, Ming Chou, Hui Chen
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Patent number: 6586016Abstract: The present invention provides Chinese herbal compositions, ST 188L and method for prevention and treatment of cancers and infectious diseases. The Chinese herbal compositions comprise a formulation prepared ratably from a group of herbal plants consisting essentially of Ecchinops grijissii, Cirsium segetum Bge, Solanum indicum Linn, Lonicerae flos, and Zizyphi fructus. ST188L appeared to be activated in vivo to stimulate the activity of NK cells and LAK cells as shown by the increases in cytolytic activity of peripheral blood mononuclear cells isolated from volunteers after intake of ST 188L toward target cells, such as K562, Daudi, HepG2 and HBV transfected HepG2-2215 in a dose dependent manner. ST 188L has been proven to be effective on eradicating malignancy in a cancer patient by enhancing said patients' endogenous immune system to keep said patient cancer free for more than ten years.Type: GrantFiled: September 13, 2001Date of Patent: July 1, 2003Assignee: Sagittarius Life Science Corp.Inventors: Yi Ming Tsai, Kou Mark Hwang, Suying Liu
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Patent number: D975403Type: GrantFiled: September 28, 2022Date of Patent: January 17, 2023Assignee: TOLOCO INCInventor: Suying Liu
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Patent number: D975871Type: GrantFiled: September 27, 2022Date of Patent: January 17, 2023Inventor: Suying Liu
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Patent number: D993620Type: GrantFiled: November 30, 2022Date of Patent: August 1, 2023Inventor: Suying Liu