Abstract: The Agastache rugosa and licorice complex mixture of the present invention has the synergy effects for the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity and therefore it can be widely utilized as a composition for the prevention or treatment of respiratory diseases.

Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g.

Abstract: In an embodiment an autonomous driving control apparatus includes a memory configured to store high definition map information and a processor electrically connected to the memory, wherein the processor is configured to generate a grid map based on a first driving route in an intersection included in the high definition map information based on a detected moving object and on the first driving route of the vehicle, to determine a drivable area with regard to the moving object and to generate a second driving route in the drivable area based on the grid map.

Abstract: A transportation head for a microchip transfer device capable of minimizing mechanical and chemical damage to a microchip, a microchip transfer device having same, and a transfer method thereby, and the transportation head includes a head body having a pickup area and a dummy area; a first protruding pin disposed in the pickup area of the head body; and a liquid droplet attached to the first protruding pin.

Abstract: The present invention relates to a composition for hangover relief, comprising a noni fruit extract or a fraction thereof, and more specifically provides a noni fruit extract or a fraction thereof, which is prepared using a certain concentration of ethanol as an extraction solvent, to contain a large amount of polysaccharides having excellent hangover relieving functionality and an average molecular weight of 8 kDa to 10 kDa.

Abstract: In an embodiment an apparatus includes a path generator provided in a vehicle, wherein the path generator is configured to generate, based on a minimum turning radius of the vehicle, a default U-turn path and to generate a final U-turn path based on a path following control reference point of the vehicle which is based on the generated default U-turn path, and a controller configured to control autonomous driving of the vehicle to follow the generated final U-turn path.

Abstract: An embodiment apparatus for generating a U-turn path of a vehicle includes a path generator provided in the vehicle and configured to determine a deflection direction and a deflection distance to avoid a collision during a U-turn process, the deflection direction and the deflection distance being based on a minimum turning radius according to a specific reference point of the vehicle and to generate the U-turn path in which the deflection direction and the deflection distance are reflected, and a controller configured to control autonomous driving of the vehicle to follow the generated U-turn path.

Abstract: The present invention relates to a composition for enhancing immunity or a composition for preventing or ameliorating neurodegenerative diseases, both of which contain, as an active ingredient, a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof.

Abstract: Disclosed are an apparatus and method for controlling a vehicle. The apparatus may include a sensor that detects a boundary of a road, storage that stores a road map, and a controller. The controller may determine start and end points of a first U-turn path based on a U-turn lane link in the road map, determine an arc path based on the start and end points, determine a second U-turn path centered on a front bumper based on the arc path, determine an offset based on a center point of the turning path and a center point of the road boundary, and determine a third U-turn path by applying the offset to the second U-turn path. Accordingly, stability of autonomous driving may be improved by accurately determining a road boundary in a U-turn area and generating a U-turn driving path in consideration of the turning radius of the vehicle.

Abstract: The present invention provides a system for collecting tripper room fugitive dust of a power plant coal transfer facility, wherein the system includes an entrance dust collection module disposed at the entrance of a tripper room to block dust; a tripper car configured to move along a transfer conveyor disposed inside the tripper room and transfer fuel introduced through the entrance to silos; and a main dust collection module configured prevent spread of dust by removing dust in response to movement of the tripper car and adjusting the pressure at the point where dust is generated.

Abstract: The present invention relates to a composition for the prevention or treatment of respiratory diseases containing an Agastache rugosa and licorice extract as an active ingredient, and more specifically, the present invention relates to a composition for the prevention or treatment of respiratory diseases caused by fine dust containing an extract, in which Agastache rugosa and licorice are mixed at a weight ratio of 1:1 to 6:1, as an active ingredient. The Agastache rugosa and licorice extract of the present invention has the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity.

Abstract: The present invention relates to a composition for the prevention or treatment of respiratory diseases containing an Agastacherugosa and licorice extract as an active ingredient, and more specifically, the present invention relates to a composition for the prevention or treatment of respiratory diseases caused by fine dust containing an extract, in which Agastacherugosa and licorice are mixed at a weight ratio of 1:1 to 6:1, as an active ingredient. The Agastacherugosa and licorice extract of the present invention has the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity.

Abstract: The present invention relates to a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, and a use of a noni fruit extract or a fraction thereof, and more specifically, the present invention provides a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, including preparing a noni fruit extract by using ethanol in a specific concentration range as an extraction solvent, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, a pharmaceutical composition for enhancing immunity including the extract or a fraction thereof, a health functional food composition including the same constitution, a method of enhancing immunity using the extract or a fraction thereof, and a use of the extract or a fraction thereof in preparati

Abstract: The present invention relates to a functional food composition for enhancing muscular function and exercise performance and a method for preparing same. According to the present invention, provided is a composition which enables increased generation of factors associated with myogenesis and energy metabolism and thus enhances exercise performance and muscular function. More particularly, mitochondria and muscle cell synthesis is increased and muscular atrophy is inhibited, and thus muscle exercise effects can be increased and fatigue is reduced. The composition can be applied as a health function composition to various fields such as foods.

Abstract: A composition for strengthening a skin barrier or moisturizing skin is provided. The composition includes tilianin. The composition may be a food, a health functional food composition, a quasi-drug composition and/or a composition for external use on the skin. The composition increases the contents of moisture and hyaluronic acid in the skin and exhibits an upregulating effect on HAS. A method for strengthening a skin barrier or enhancing skin moisture using tilianin, and provides a use of tilianin in the preparation of food or medicine for strengthening a skin barrier or enhancing skin moisture are also provided.

Abstract: Provided are a method for preventing or treating photoaging of skin, including: administering a composition comprising an effective amount of an extract of Agastache rugosa O Kuntze to a subject in need thereof. The composition decreases expression of matrix metalloproteinases (MMPs) induced by ultraviolet B (UVB) irradiation; decreases expression of mitogen-activated protein kinase (MAPK)/activator protein-1 (AP-1) signaling; improves collagen synthesis; decreases skin inflammation induced by NF-?B; and decreases oxidative stress induced by UVB irradiation.

Abstract: The present invention relates to a composition for enhancing immunity or a composition for preventing or ameliorating neurodegenerative diseases, both of which contain, as an active ingredient, a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof.

Abstract: The present invention relates to a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, and a use of a noni fruit extract or a fraction thereof, and more specifically, the present invention provides a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, including preparing a noni fruit extract by using ethanol in a specific concentration range as an extraction solvent, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, a pharmaceutical composition for enhancing immunity including the extract or a fraction thereof, a health functional food composition including the same constitution, a method of enhancing immunity using the extract or a fraction thereof, and a use of the extract or a fraction thereof in preparati

Abstract: A display inside mirror includes a housing configured to be secured to a windshield glass, the housing having an opening formed therein, a mirror part disposed in the opening, a display unit disposed so as to face the mirror part, a control unit disposed adjacent to the display unit so as to control the transmission of a display image, a tilting lever disposed at one end of the housing so as to tilt the mirror part, and a switch unit disposed at the tilting lever so as to allow the power from the control unit to be selectively applied to the display unit.

Abstract: The present invention relates to a composition for preventing or treating a muscle disorder, which includes a Chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the Chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the Chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1?, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance.