Patents by Inventor Sudheer Babu Vaddela

Sudheer Babu Vaddela has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MASP-2 INHIBITORS AND METHODS OF USE
    Publication number: 20240092788
    Abstract: The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds, and methods of making and using such compounds.
    Type: Application
    Filed: September 6, 2023
    Publication date: March 21, 2024
    Applicant: Omeros Corporation
    Inventors: Neil S. Cutshall, Jennifer Lynn Gage, Sara Rebecca Goldstein, Santosh Kumar Keshipeddy, Do Yeon Kwon, Robert Huerta Lemus, Thomas L. Little, Markus Metz, Jeremiah H. Nguyen, Peter Kurt Nollert Von Specht, Loren Michael Price, Jennifer Tsoung, Sudheer Babu Vaddela
  • MASP-2 inhibitors and methods of use
    Patent number: 11807641
    Abstract: The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds, and methods of making and using such compounds.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: November 7, 2023
    Assignee: Omeros Corporation
    Inventors: Michael Cicirelli, Neil S. Cutshall, Jennifer Lynn Gage, Sara Rebecca Goldstein, Santosh Kumar Keshipeddy, Do Yeon Kwon, Robert Huerta Lemus, Thomas L. Little, Markus Metz, Jeremiah H. Nguyen, Peter Kurt Nollert von Specht, Loren Michael Price, Jennifer Tsoung, Sudheer Babu Vaddela
  • MASP-2 INHIBITORS AND METHODS OF USE
    Publication number: 20230145071
    Abstract: The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds.
    Type: Application
    Filed: November 30, 2022
    Publication date: May 11, 2023
    Inventors: Neil S. Cutshall, Jennifer Lynn Gage, Franz A. Gruswitz, Juhienah Khalaf, Thomas L. Little, Markus Metz, Jeremiah H. Nguyen, Peter Kurt Nollert von Specht, Jennifer Tsoung, Michael Cicirelli, Sara Rebecca Goldstein, Santosh Kumar Keshipeddy, Do Yeon Kwon, Robert Huerta Lemus, Sudheer Babu Vaddela
  • FE/CU-MEDIATED KETONE SYNTHESIS
    Publication number: 20230135188
    Abstract: Provided herein are methods for preparing ketone-containing organic molecules. The methods are based on novel iron/copper-mediated (“Fe/Cu-mediated”) coupling reactions. The Fe/Cu-mediated coupling reaction can be used in the preparation of complex molecules, such as halichondrins and analogs thereof. In particular, the Fe/Cu-mediated ketolization reactions described herein are useful in the preparation of intermediates en route to halichondrins.
    Type: Application
    Filed: November 9, 2022
    Publication date: May 4, 2023
    Applicant: President and Fellows of Harvard College
    Inventors: Yoshito Kishi, Kenzo Yahata, Vemula Praveen Kumar, Sudheer Babu Vaddela
  • MASP-2 inhibitors and methods of use
    Patent number: 11584714
    Abstract: The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: February 21, 2023
    Assignee: OMEROS CORPORATION
    Inventors: Neil S. Cutshall, Jennifer Lynn Gage, Franz A. Gruswitz, Juhienah Khalaf, Thomas L. Little, Markus Metz, Jeremiah H. Nguyen, Peter Kurt Nollert von Specht, Jennifer Tsoung, Michael Cicirelli, Sara Rebecca Goldstein, Santosh Kumar Keshipeddy, Do Yeon Kwon, Robert Huerta Lemus, Sudheer Babu Vaddela
  • Fe/Cu-mediated ketone synthesis
    Patent number: 11498892
    Abstract: Provided herein are methods for preparing ketone-containing organic molecules. The methods are based on novel iron/copper-mediated (“Fe/Cu-mediated”) coupling reactions. The Fe/Cu-mediated coupling reaction can be used in the preparation of complex molecules, such as halichondrins and analogs thereof. In particular, the Fe/Cu-mediated ketolization reactions described herein are useful in the preparation of intermediates en route to halichondrins.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: November 15, 2022
    Assignee: President and Fellows of Harvard College
    Inventors: Yoshito Kishi, Kenzo Yahata, Vemula Praveen Kumar, Sudheer Babu Vaddela
  • FE/CU-MEDIATED KETONE SYNTHESIS
    Publication number: 20210179522
    Abstract: Provided herein are methods for preparing ketone-containing organic molecules. The methods are based on novel iron/copper-mediated (“Fe/Cu-mediated”) coupling reactions. The Fe/Cu-mediated coupling reaction can be used in the preparation of complex molecules, such as halichondrins and analogs thereof. In particular, the Fe/Cu-mediated ketolization reactions described herein are useful in the preparation of intermediates en route to halichondrins.
    Type: Application
    Filed: May 9, 2018
    Publication date: June 17, 2021
    Applicant: President and Fellows of Harvard College
    Inventors: Yoshito Kishi, Kenzo Yahata, Vemula Praveen Kumar, Sudheer Babu Vaddela
  • MASP-2 INHIBITORS AND METHODS OF USE
    Publication number: 20210171531
    Abstract: The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds, and methods of making and using such compounds.
    Type: Application
    Filed: December 4, 2020
    Publication date: June 10, 2021
    Inventors: Michael CICIRELLI, Neil S. CUTSHALL, Jennifer Lynn GAGE, Sara Rebecca GOLDSTEIN, Santosh Kumar KESHIPEDDY, Do Yeon KWON, Robert Huerta LEMUS, Thomas L. LITTLE, Markus METZ, Jeremiah H. NGUYEN, Peter Kurt NOLLERT VON SPECHT, Loren Michael PRICE, Jennifer TSOUNG, Sudheer Babu VADDELA
  • FE/CU-MEDIATED KETONE SYNTHESIS
    Publication number: 20200165183
    Abstract: Provided herein are methods for preparing ketone-containing organic molecules. The methods are based on novel iron/copper-mediated (“Fe/Cu-mediated”) coupling reactions. The Fe/Cu-mediated coupling reaction can be used in the preparation of complex molecules, such as halichondrins and analogs thereof. In particular, the Fe/Cu-mediated ketolization reactions described herein are useful in the preparation of intermediates en route to halichondrins.
    Type: Application
    Filed: May 9, 2018
    Publication date: May 28, 2020
    Applicant: President and Fellows of Flarvard College
    Inventors: Yoshito Kishi, Kenzo Yahata, Vemula Praveen Kumar, Sudheer Babu Vaddela
  • MASP-2 INHIBITORS AND METHODS OF USE
    Publication number: 20190367452
    Abstract: The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds.
    Type: Application
    Filed: May 29, 2019
    Publication date: December 5, 2019
    Inventors: Neil S. Cutshall, Jennifer Lynn Gage, Franz A. Gruswitz, Juhienah Khalaf, Thomas L. Little, Markus Metz, Jeremiah H. Nguyen, Peter Kurt Nollert von Specht, Jennifer Tsoung, Michael Cicirelli, Sara Rebecca Goldstein, Santosh Kumar Keshipeddy, Do Yeon Kwon, Robert Huerta Lemus, Sudheer Babu Vaddela