Patents by Inventor Sui-yuan Chang

Sui-yuan Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMANIZED ACE2-FC FUSION PROTEIN FOR TREATMENT AND PREVENTION OF SARS-COV-2 INFECTION
    Publication number: 20230235007
    Abstract: Disclosed herein are ACE2-Fc fusion polypeptides that contain at least one binding site for a spike protein of a coronavirus and methods of using such for therapeutic and/or diagnostic purposes. Also provided herein are methods for producing such fusion polypeptides.
    Type: Application
    Filed: June 15, 2021
    Publication date: July 27, 2023
    Inventors: Pan-Chyr YANG, Sui-Yuan CHANG, Kuo-Yen HUANG
  • METHOD AND COMBINATION FOR THE SUPPRESSION OF COVID-19 VIRUS
    Publication number: 20230122049
    Abstract: Provided is a method for treating a SARS-CoV2 3CLpro-related disease in a subject in need thereof by blocking dimerization of 3C-like main protease (3CLpro) of the SARS-CoV2, including administering to the subject a first agent which binds to a first binding site of a SARS-CoV2 3CLpro complex and a second agent which binds to a second binding site of the SARS-CoV2 3CLpro complex, wherein the first binding site and the second binding site are functionally different sites in the three-dimensional structure of the SARS-CoV2 3CLpro complex. Also provided is a pharmaceutical combination including the first agent and the second agent for suppressing SARS-CoV2, thereby alleviating COVID-19.
    Type: Application
    Filed: October 20, 2022
    Publication date: April 20, 2023
    Inventors: Lee-Wei YANG, Kun-Lin TSAI, Bang-Chieh HUANG, Yi-Yun CHENG, Sui-Yuan CHANG
  • COUMARIN COMPOUNDS AND THEIR USE FOR TREATING VIRAL INFECTION
    Publication number: 20120046238
    Abstract: A method for treating an infection with a virus. The method includes administering to a subject in need thereof an effective amount of one or more coumarin compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, and X are defined herein. Also disclosed is a pharmaceutical composition including a coumarin compound.
    Type: Application
    Filed: November 10, 2011
    Publication date: February 23, 2012
    Applicant: National Health Research Institutes
    Inventors: Hsing-Pang Hsieh, Tsu-An Hsu, Jiann-Yih Yeh, Jim-Tong Horng, Shin-Ru Shih, Sui-yuan Chang, Yu-Sheng Chao
  • COUMARIN COMPOUNDS AND THEIR USE FOR TREATING VIRAL INFECTION
    Publication number: 20090312406
    Abstract: A method for treating an infection with a virus. The method includes administering to a subject in need thereof an effective amount of one or more coumarin compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, and X are defined herein. Also disclosed is a pharmaceutical composition including a coumarin compound.
    Type: Application
    Filed: June 10, 2009
    Publication date: December 17, 2009
    Inventors: Hsing-Pang Hsieh, Tsu-An Hsu, Jiann-Yih Yeh, Jim-Tong Horng, Shin-Ru Shih, Sui-yuan Chang, Yu-Sheng Chao
  • Anti-virus compounds
    Publication number: 20040044069
    Abstract: This invention features a method for treating infection by herpesvirus.
    Type: Application
    Filed: May 23, 2003
    Publication date: March 4, 2004
    Inventors: Tsu-An Hsu, Hsing-Pang Hsieh, Li-Jung Juan, Sui-Yuan Chang, Yueh-Hsiung Kuo