Abstract: Described herein are compounds of Formula (I), or a pharmaceutically acceptable salt, solvate, diastereomeric mixture, or individual enantiomers thereof, that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Abstract: Disclosed is a method for forming a three-dimensional (3D) model of skin and mandible by automatic medical image segmentation which is performed in an automatic image segmentation and model formation server. The method includes (a) receiving 3D medical image data that is a set of two-dimensional (2D) images for horizontal planes of a face, (b) obtaining a contrast histogram based on distribution of contrasts of the 3D medical image data, and segmenting the 3D medical image data for the face into multiple regions separated into at least one partial region based on the contrast histogram, (c) extracting only the face by removing portions other than the face from the multiple regions for the face, and extracting a skin region of the face, (d) extracting the mandible from each of the 2D images for the horizontal planes of the face through a 2D detailed segmentation technique using an active contour method based on a level set function, and (e) reconstructing the extracted skin region and mandible as the 3D model.

Abstract: The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1 receptor-associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, microbial infections or diseases and viral infections or diseases.

Abstract: Disclosed is a method for forming a three-dimensional (3D) model of skin and mandible by automatic medical image segmentation which is performed in an automatic image segmentation and model formation server. The method includes (a) receiving 3D medical image data that is a set of two-dimensional (2D) images for horizontal planes of a face, (b) obtaining a contrast histogram based on distribution of contrasts of the 3D medical image data, and segmenting the 3D medical image data for the face into multiple regions separated into at least one partial region based on the contrast histogram, (c) extracting only the face by removing portions other than the face from the multiple regions for the face, and extracting a skin region of the face, (d) extracting the mandible from each of the 2D images for the horizontal planes of the face through a 2D detailed segmentation technique using an active contour method based on a level set function, and (e) reconstructing the extracted skin region and mandible as the 3D model.

Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Abstract: The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1 receptor-associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, microbial infections or diseases and viral infections or diseases.

Abstract: A phosphor-containing curable silicone composition giving a curable hotmelt film and the curable hotmelt film used for light-emitting semiconductor device are provided. The composition containing the phosphor gives a tack free film at room temperature by half cure and the film is easy to fabricate the desired forms. The fabricated film is easy to pick up them from the support substrate and transferred onto a light emitting semiconductor device at room temperature. The laminated film is molten followed by cured by heating to give excellent permanent adhesion to the device surface.

Abstract: The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1 receptor-associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, microbial infections or diseases and viral infections or diseases.

Abstract: The present invention relates to certain substituted tricyclic acid derivatives of Formula (I) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1-associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, myocardial ischemia-reperfusion injury, hypertensive nephropathy, glomerulosclerosis, gastritis, polymyositis, thyroiditis, vitiligo, hepatitis, biliary cirrhosis, microbial infections and associated diseases, viral infections and associated diseases, diseases and disorders mediated by lymphocytes, auto immune diseases, inflammatory diseases, and cancer.

Abstract: Provided is a liquid composition for treating stomatitis, the liquid composition including: an epidermal growth factor; an adhesive polymer; and at least one stabilizer selected from the group consisting of ethylenediaminetetraacetic acid (EDTA) and salts thereof, histidine, lysine and inorganic acid salts thereof, arginin and inorganic acid salts thereof, and dextran. The liquid composition includes a stabilizer selected from EDTA (or salts thereof) and a certain amino acid (or inorganic acid salts thereof) and thus, physicochemical and biological stability of the epidermal growth factor can be substantially increased. Thus, the liquid composition can be stored and distributed for a long period of time. The stabilized composition includes an adhesive polymer, and thus, when ejected in a spray form in the mouth of a user, the liquid composition can be quickly attached to an inflammation site and exhibits effectiveness for a long period of time.

Abstract: The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1 receptor-associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, microbial infections or diseases and viral infections or diseases.

Abstract: The present invention relates to certain substituted tricyclic acid derivatives of Formula (I) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1 -associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, myocardial ischemia-reperfusion injury, hypertensive nephropathy, glomerulosclerosis, gastritis, polymyositis, thyroiditis, vitiligo, hepatitis, biliary cirrhosis, microbial infections and associated diseases, viral infections and associated diseases, diseases and disorders mediated by lymphocytes, auto immune diseases, inflammatory diseases, and cancer.

Abstract: Disclosed herein is a wireless communication method for a magnetic field communication network. The wireless communication method is performed by a coordinator on the magnetic field communication network. The wireless communication method includes transmitting a request signal used to request response to each of sensor nodes; selecting any one of response signals received from the sensor nodes; transmitting an acknowledgement signal to a sensor node corresponding to the response signal; selecting any one of response signals transmitted again from sensor nodes which did not receive the acknowledgement signal; and transmitting an acknowledgement signal to a sensor node corresponding to the selected response signal.

Abstract: Disclosed is a charging method of a multi-node wireless charging system using magnetic field communication capable of effectively charging a plurality of nodes using the magnetic field communication. The magnetic field communication protocol for wireless charging is prepared and thus, an appropriate wireless charging device may be selected and charged for an appropriate time. The wireless charging method of the present invention includes: transmitting an association request frame; receiving an association response frame from the wireless charging devices; transmitting a charging requirement request frame; receiving a charging requirement response frame from the wireless charging devices; transmitting a charging preparation request frame; and transmitting power during a receiving period of the charging preparation response frame for the charging preparation request frame.

Abstract: Provided are a culture medium of an adipose-derived stem cell, a method for preparing the same, and a composition for promoting hair growth, in which the composition includes the culture medium. The adipose-derived stem cell (ADSC-T) according to the present invention exhibits long lifespan, improved cell proliferation rate, and extended proliferation period, as compared with a primary adipose-derived stem cell (ADSC), and thus, the adipose-derived stem cell (ADSC-T) can be usefully used for the study about the adipose-derived stem cell and the mass production of the culture medium of the adipose-derived stem cell. In addition, according to the present invention, the culture medium of the adipose-derived stem cell (ADSC-T) that expresses a T antigen of SV40 exhibits excellent hair growth effectiveness and can be usefully used as a raw material for the hair loss prevention and hair growing agents.

Abstract: An efficient security related procedure is disclosed. A plurality of service data units (SDUs) having the same priority is multiplexed to one unit signal. The unit signal is ciphered using a mask generated by a first parameter combination. The receiver simultaneously deciphers the multiplexed service data units (SDUs), such that a Layer-2 (L2) processing time is efficiently reduced and the problems encountered by signals vulnerable to security can be efficiently solved.

Abstract: A method and apparatus for measuring a cell a wireless communication system are disclosed. The method includes receiving measurement configuration information for a plurality of frequencies from a BS, without a dedicated connection between a UE and a network, and measuring cells using the plurality of frequencies according to the measurement configuration information.