Abstract: A ferrite core according to an embodiment of the present invention includes a plurality of grains including Mn at 30 to 40 mol %, Zn at 5 to 15 mol %, and Fe at 50 to 60 mol %, and a plurality of grain boundaries disposed between the plurality of grains, wherein the plurality of grains and the plurality of grain boundaries include Co, Ni, SiO2, CaO, and Ta2O5, content of the Co and the Ni in the plurality of grains is two or more times higher than content of the Co and the Ni in the plurality of grain boundaries, content of the SiO2, the CaO, and the Ta2O5 in the plurality of grain boundaries is two or more times higher than content of the SiO2, the CaO, and the Ta2O5 in the plurality of grains, a magnetic permeability is 3000 or more, and a core loss is 800 or less.

Abstract: An embodiment of the present invention discloses a camera actuator comprising: a housing; a mover disposed in the housing and including protrusions on one surface which protrude toward the housing; and a driving unit disposed in the housing and rotating the mover on the basis of a first direction or a second direction perpendicular to the first direction, wherein the protrusions comprise: a first protrusion disposed on the one surface; a second protrusion spaced apart from the first protrusion; and a third protrusion separated from the first protrusion by a distance greater than from the second protrusion, and wherein the housing comprises: a groove in which the first protrusion is seated on an inner surface corresponding to the one surface; a first hole through which the second protrusion passes; and a second hole through which the third protrusion passes, wherein a side surface of the second protrusion is spaced apart from the first hole, and the housing includes a protruding part disposed on a side of the

Abstract: A method of mitigating motion sickness in a passenger including learning a motion sickness prediction model based on state information of a vehicle or the passenger, reaction information of the passenger, and motion sickness-related information, predicting reactions of the passenger to a current state of the vehicle or the passenger and possibility of motion sickness using the learned motion sickness prediction model, and providing information on the motion sickness mitigation methods to the passenger or controlling the vehicle based on the predicted reactions of the passenger and possibility of motion sickness. The motion sickness-related information includes one or more of a determination result of whether motion sickness occurs to the passenger, motion sickness state information, and motion sickness reaction information.

Abstract: A method of manufacturing a multilayer metal plate by electroplating includes a first forming operation of forming one of a first metal layer and a second metal layer on a substrate by electroplating, wherein the second metal layer is less recrystallized than the first metal layer, the second metal layer is comprised of nanometer-size grains, and the second metal layer has a higher level of tensile strength than the first metal layer; and a second forming operation of forming, by electroplating, a third metal layer not formed in the first forming operation on a surface of one of the first metal layer and the second metal layer formed in the first forming operation.

Abstract: A method for controlling driving of a hybrid electric vehicle includes collecting driving data while the hybrid electric vehicle is driven, determining whether the hybrid electric vehicle enters a first mode corresponding to emergency driving of the hybrid electric vehicle or a second mode corresponding to control in preparation for the emergency driving, and controlling the hybrid electric vehicle in accordance with a mode that the hybrid electric vehicle enters among the first mode and the second mode.

Abstract: An embodiment of the present invention discloses a camera actuator comprising: a housing; a mover on which an optical member sits and which is disposed inside the housing; a ball part including a first ball and a second ball and disposed between the housing and the mover; and a driving unit that is disposed inside the housing to drive the mover, wherein the mover includes a first protrusion extending toward the housing and including a recess. The recess includes: a side surface on which the ball part sits and on which at least a portion of the recess is spaced apart from the ball part; and a bottom surface in contact with the side surface.

Abstract: A substrate processing apparatus includes: a conveyor belt configured to have an outer surface on which a bottom surface of a substrate is seated; and a polishing head unit configured to face an upper surface of the substrate, wherein the polishing head unit includes: a polishing head connected to a driver; a polishing pad configured to face the polishing head; a polishing pad fixing ring disposed between the polishing head and the polishing pad; and a temperature sensor configured to overlap the polishing pad fixing ring and to be spaced apart from the polishing pad fixing ring.

Abstract: The present invention relates to: a compound of chemical formula 1, a pharmaceutically acceptable salt thereof or an isomer thereof; and a pharmaceutical composition for treating or preventing metabolic diseases, containing same as an active ingredient. [Chemical formula 1] In chemical formula 1, R1 represents an unsubstituted or C1-C5 alkyl-substituted C3-C7 heterocycloalkyl containing one to three N atoms, R2 and R3 independently represent hydrogen, a halogen or a C1-C5 alkyl, R4 represents —(CH2)mCO2H, m, p and q are each independently an integer of 0-2, X represents N or C—CN, Y represents CH2 or O, and Z represents CH2 or a single bond.

Abstract: The present disclosure relates to a use of JULGI in diagnosing and treating guanine quadruplex-related disease and, more particularly, to a guanine-quadruplex (G-quadruplex) detecting composition comprising JULGI protein or a protein having a homology of 80% or higher to the JULGI protein, a diagnostic composition comprising the detecting composition, a diagnostic kit comprising the diagnostic composition, a method for providing information for diagnosis of a neurodegenerative disease, cancer, or a viral infection disease which are in pathological correlation with G-quadruplex, and a pharmaceutical composition for prevention or treatment of a neurodegenerative disease, cancer, or a viral infection disease, the pharmaceutical composition comprising JULGI protein, a protein having a homology of 80% or more with the JULGI protein, or a mutant protein thereof.

Abstract: The present disclosure relates to a technology of producing a sculpture in a 3D stereoscopic space filled with a transparent material. The sculpture may be produced through a process of preparing a desired number of 2D plans acquired by dividing a 3D plan of the sculpture and a plurality of transparent plates corresponding to the number of the 2D plans, forming the shapes of corresponding regions by stacking representation materials on the corresponding transparent plates, joining the representation materials to the corresponding transparent plates, or making scratches on the corresponding transparent plates, and stacking the transparent plates having the shapes formed thereon, and can precisely represent shapes through various representation techniques or be repeatedly reproduced.

Abstract: The present invention relates to a compound of Formula 1, a pharmaceutically acceptable salt or isomer thereof, a pharmaceutical composition including the same, and a use. The compound of Formula 1 according to the present invention has ketohexokinase (KHK) inhibitory activity, and is effectively used for preventing or treating metabolic disease such as diabetes, diabetic complications, obesity, nonalcoholic fatty liver disease, and fatty hepatitis.

Abstract: The present application relates to an indole compound represented by formula (1): a pharmaceutically acceptable salt or isomer thereof, a composition for prevention or treatment of necrosis and necrosis-associated diseases, and a method for preparing the composition, the composition comprising the indole compound or the pharmaceutically acceptable salt or isomer thereof as an active ingredient.

Abstract: The present invention relates to a technology which enables a desired shape to be freely represented using sculpture components in a three-dimensional space filled with a transparent material. The present invention is characterized in that, when a sculpture is manufactured by installing, in a three-dimensional space, a text, a picture, a model, and a real object consisting of at least one of points, lines, surfaces, and solids, the shape of the sculpture can be freely represented using a transparent carrier containing at least one of the text, the picture, the model, and the real object, and a transparent carrier serving as a fixing means.

Abstract: The present invention relates to a synthesis method of preventing the formation of impurities and byproducts in the synthesis of tenofovir disoproxil fumarate (Teno-DF) used as a medicine for hepatitis B and HIV treatment due to its function to promote bioactivities. In the synthesis method of the present invention, an ion-exchange resin (Dowex 50W hydrogen form, sulfonic acidic cation exchange resin) is used to enhance the yield and purity of the compound. The present invention also relates to a method of preparing an oral dissolving film dosage form in the manufacture of a medicine using the tenofovir compound with high purity obtained by the synthesis method of the present invention as an effective ingredient.

Abstract: The present invention relates to a novel compound having GPR40 receptor agonist activity that promotes insulin secretion and inhibits blood sugar rise after glucose loading, and is thereby useful for the treatment of diabetes and complications thereof, the preparation method thereof and pharmaceutical composition containing them as an active ingredient.

Abstract: The present invention relates to an indole amide compound represented by formula (1), a pharmaceutically acceptable salt or isomer thereof, a composition for prevention or treatment of necrosis and necrosis-associated diseases, and a method for preparing the composition, the composition comprising the indole compound or the pharmaceutically acceptable salt or isomer thereof as an active ingredient.

Abstract: The present invention relates to a synthesis method of preventing the formation of impurities and byproducts in the synthesis of tenofovir disoproxil fumarate (Teno-DF) used as a medicine for hepatitis B and HIV treatment due to its function to promote bioactivities. In the synthesis method of the present invention, an ion-exchange resin (Dowex 50W hydrogen form, sulfonic acidic cation exchange resin) is used to enhance the yield and purity of the compound. The present invention also relates to a method of preparing an oral dissolving film dosage form in the manufacture of a medicine using the tenofovir compound with high purity obtained by the synthesis method of the present invention as an effective ingredient.

Abstract: The present invention relates to novel compounds of Formula 1 as sphingosine-1-phosphate receptor agonists which can be effectively used for the treatment of autoimmune diseases, a method for preparing the same, and a pharmaceutical composition comprising the same as an active component. The compounds according to the present invention are effective on extensive autoimmune diseases and chronic inflammatory diseases including relapsing-remitting multiple sclerosis, and can also be used for treating or preventing immunoregulation disorders.

Abstract: The present invention relates to an indole compound represented by formula (1), a pharmaceutically acceptable salt or isomer thereof, a composition for prevention or treatment of necrosis and necrosis-associated diseases, and a method for preparing the composition, the composition comprising the indole compound or the pharmaceutically acceptable salt or isomer thereof as an active ingredient.

Abstract: The present invention relates to an indole amide compound represented by formula (1), a pharmaceutically acceptable salt or isomer thereof, a composition for prevention or treatment of necrosis and necrosis-associated diseases, and a method for preparing the composition, the composition comprising the indole compound or the pharmaceutically acceptable salt or isomer thereof as an active ingredient.