Patents by Inventor Sung June Yoon
Sung June Yoon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240143927Abstract: Provided are a method for generating a summary and a system therefor. The method according to some embodiments may include calculating a likelihood loss for a summary model using a first text sample and a first summary sentence corresponding to the first text sample, calculating an unlikelihood loss for the summary model using a second text sample and the first summary sentence, the second text sample being a negative sample generated from the first text sample, and updating the summary model based on the likelihood loss and the unlikelihood loss.Type: ApplicationFiled: October 26, 2023Publication date: May 2, 2024Applicants: SAMSUNG SDS CO., LTD., SEOUL NATIONAL UNIVERSITY R&DB FOUNDATIONInventors: Sung Roh YOON, Bong Kyu HWANG, Ju Dong KIM, Jae Woong YUN, Hyun Jae LEE, Hyun Jin CHOI, Jong Yoon SONG, Noh II PARK, Seong Ho JOE, Young June GWON
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Patent number: 6762189Abstract: The present invention relates to novel 5-pyrimidinecarboxamide derivatives and the pharmaceutical compositions containing said derivatives, and more specifically, to 5-pyrimidinecarboxamide derivatives and their pharmacutically able salts, the process for preparing them, and the pharmaceutical compositions containing said compounds as active ingredients. In particular, said 5-pyrimidinecarboxamide derivatives of the present invention, due to their inhibitory activity against the proliferation of human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV), can be used as a therapeutic agent as well as a preventive agent for hepatitis B and acquired immune deficiency syndrome (AIDS).Type: GrantFiled: May 24, 2002Date of Patent: July 13, 2004Assignee: Dong Wha Pharm. Ind. Co., Ltd.Inventors: Sung June Yoon, Sang Wook Lee, Nam Doo Kim, Yong Kyun Park, Geun Hyung Lee, Jong Woo Kim, Sang Jin Park, Hee Jeoung Park, Hwan Bong Jang
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Patent number: 6753430Abstract: The present invention relates to optically active quinoline carboxylic acid derivatives, their pharmaceutically acceptable salts, their solvates, and a process for the preparation thereof. More specifically, the present invention relates to optically active quinoline carboxylic acid derivatives containing 4-aminomethyl-4methyl-3-(Z)-alkoxyiminopyrrolidine substituents causing optical activity at the 7-position of the quinolone nuclei. As the compounds of the present invention have superior antibacterial activity and pharmacokinetic profiles to their enantiomers, their racemates and conventional antibacterial agents, with nearly no phototoxicity, the compounds of this invention are useful for antibacterial agents.Type: GrantFiled: June 20, 2003Date of Patent: June 22, 2004Assignee: Dong Wha Pharm. Ind. Co., LtdInventors: Sung June Yoon, Yong Ho Chung, Chi Woo Lee, Jin Soo Lee, Nam Doo Kim, Yoon Ho Jin, Wan Jin Song, Ik Hoe Kim, Wang Yong Yang, Dong Rack Choi, Jung Han Shin
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Patent number: 6743795Abstract: The present invention relates to novel 3-nitropyridine derivatives, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same as active ingredients. Methods of preparing the derivatives and pharmaceutical compositions containing the same are also disclosed. The 3-nitropyridine derivatives of the present invention, due to their inhibitory activity against the proliferation of human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV), can be used as therapeutic agents as well as preventive agents for hepatitis B and acquired immune deficiency syndrome (AIDS).Type: GrantFiled: May 24, 2002Date of Patent: June 1, 2004Assignee: Dong Wha Pharm. Ind. Co. Ltd.Inventors: Sung June Yoon, Sang Wook Lee, Nam Doo Kim, Yong Kyun Park, Geun Hyung Lee, Jong Woo Kim, Sang Jin Park, Hee Jeoung Park, Dong Hyuk Shin
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Publication number: 20040029915Abstract: The present invention relates to optically active quinoline carboxylic acid derivatives, their pharmaceutically acceptable salts, their solvates, and a process for the preparation thereof. More specifically, the present invention relates to optically active)quinoline carboxylic acid derivatives containing 4-aminomethyl-4-methyl-3-(Z)-alkoxyiminopyrrolidine substituents causing optical activity at the 7-position of the quinolone nuclei. As the compounds of the present invention have superior antibacterial activity and pharmacokinetic profiles to their enantiomers, their racemates and conventional antibacterial agents, with nearly no phototoxicity, the compounds of this invention are useful for antibacterial agents.Type: ApplicationFiled: June 20, 2003Publication date: February 12, 2004Inventors: Sung June Yoon, Yong Ho Chung, Chi Woo Lee, Jin Soo Lee, Nam Doo Kim, Yoon Ho Jin, Wan Jin Song, Ik Hoe Kim, Wang Yong Yang, Dong Rack Choi, Jung Han Shin
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Patent number: 6649763Abstract: The present invention relates to optically active quinoline carboxylic acid derivatives, their pharmaceutically acceptable salts, their solvates, and a process for the preparation thereof. More specifically, the present invention relates to optically active quinoline carboxylic acid derivatives containing 4-aminomethyl-4-methyl-3-(Z)-alkoxyirninopyrrolidine substituents causing optical activity at the 7-position of the quinolone nuclei. As the compounds of the present invention have superior antibacterial activity and pharmacokinetic profiles to their enantiomers, their racemates and conventional antibacterial agents, with nearly no phototoxicity, the compounds of this invention are useful for antibacterial agents.Type: GrantFiled: November 16, 2001Date of Patent: November 18, 2003Assignee: Dong Wha Pharm. Ind. Co., Ltd.Inventors: Sung June Yoon, Yong Ho Chung, Chi Woo Lee, Jin Soo Lee, Nam Doo Kim, Yoon Ho Jin, Wan Jin Song, Ik Hoe Kim, Wang Yong Yang, Dong Rack Choi, Jung Han Shin
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Patent number: 6608058Abstract: The present invention relates to novel 6-methylnicotinamide derivatives and their pharmaceutically acceptable salts, the process for preparing them, and the pharmaceutical compositions containing said compounds as active ingredients. The 6-methylnicotinamide derivatives of the present invention exhibit their inhibitory activity against the proliferation of human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV) and hepatitis C virus (HCV), such that they can be used for hepatitis B, hepatitis C and acquired immune deficiency syndrome (AIDS).Type: GrantFiled: October 10, 2002Date of Patent: August 19, 2003Assignee: Dong Wha Pharm. Ind. Co., Ltd.Inventors: Sung-June Yoon, Sang-Wook Lee, Jin-Soo Lee, Nam-Doo Kim, Geun-Hyung Lee, Hak-Dong Lee, Jong-Woo Kim, Sang-Jin Park, Hee-Jeong Park
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Publication number: 20030092709Abstract: The present invention relates to novel 6-methylnicotinamide derivatives and their pharmaceutically acceptable salts, the process for preparing them, and the pharmaceutical compositions containing said compounds as active ingredients. The 6-methylnicotinamide derivatives of the present invention exhibit their inhibitory activity against the proliferation of human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV) and Hepatitis C virus (HCV), such that they can be used for hepatitis B, hepatitis C and acquired immune deficiency syndrome (AIDS).Type: ApplicationFiled: October 10, 2002Publication date: May 15, 2003Inventors: Sung-June Yoon, Sang-Wook Lee, Jin-Soo Lee, Nam-Doo Kim, Geun-Hyung Lee, Hak-Dong Lee, Jong-Woo Kim, Sang-Jin Park, Hee-Jeong Park
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Patent number: 6488954Abstract: The present invention relates to a liquid suppository composition comprising diclofenac sodium, poloxamer and at least one polymer select from the group consisting of polyethylene oxide and polyvinylpyrrolidone. The composition provides the advantages of. (1) a feel of foreign matter or discomfort does not occur when the composition is rectally administered; and (2) administration is easy and after rectal administration, the composition is neither leaked out from the anus nor shifted into the end of large intestine.Type: GrantFiled: August 24, 2001Date of Patent: December 3, 2002Assignee: Dong Wha Pharm. Ind. Co., Ltd.Inventors: Sung June Yoon, Jei Man Ryu, Jae Hee Jung, Su Jin Cho
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Patent number: 6150390Abstract: The present invention relates to a novel 3-amino-1,2-benzoisoxazole derivatives, represented by Formula I, LTB-4[leukotriene-B-4; 5(S),12(R)-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid] receptor antagonist, process for preparation thereof, and use thereof for LTB-4 receptor antagonist or therapeutics for osteoporosis. ##STR1## (in which n is integer of 3-5).Type: GrantFiled: July 21, 1999Date of Patent: November 21, 2000Assignee: Dong Wha Pharm. Ind. Co., Ltd.Inventors: Hong-Suk Suh, Jae-Ha Ryu, Yong-Nam Han, Sung-June Yoon, Jong-Woo Kim
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Patent number: 6071734Abstract: The present invention relates to hepatitis B virus (hereinafter it refers to HBV) polymerase containing a histidine tag, RNase H enzyme derived from HBV polymerase and processes for preparation thereof. More particularly, the present invention relates to recombinant HBV polymerase, its RNase H domain with enzyme activity, expression vectors producing the enzymes in E. coli and processes for preparing the HBV polymerase and the RNase H enzyme which can be easily purified due to their histidine tags. And the present invention relates to uses of the HBV polymerase and the RNase H enzyme for screening antiviral agents.Type: GrantFiled: January 11, 1999Date of Patent: June 6, 2000Assignee: Dong Wha Pharm. Ind. Co., Ltd.Inventors: Sung-June Yoon, Jong-Woo Kim, Yong Huh, Hyune-Mo Rho, Gu-Hung Jung
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Patent number: 5968781Abstract: The present invention relates to hepatitis B virus (hereinafter it refers to HBV) polymerase containing a histidine tag, RNase H enzyme derived from HBV polymerase and processes for preparation thereof.More particularly, the present invention relates to recombinant HBV polymerase, its RNase H domain with enzyme activity, expression vectors producing the enzymes in E. coli and processes for preparing the HBV polymerase and the RNase H enzyme which can be easily purified due to their histidine tags.And the present invention relates to uses of the HBV polymerase and the RNase H enzyme for screening antiviral agents.Type: GrantFiled: August 15, 1997Date of Patent: October 19, 1999Assignee: Dong Wha Pharm. Ind. Co., Ltd.Inventors: Sung-June Yoon, Jong-Woo Kim, Yong Huh, Hyune-Mo Rho, Gu-Hung Jung
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Patent number: 5932742Abstract: The present invention relates to a novel arylsulfonylimidazolone derivative represented by the following formula (I) which shows a superior antineoplastic activity in contrast to the known sulfonylurea antitumor agents as well as little side effect: ##STR1## and its pharmaceutically acceptable salt and stereoisomer, in which - -, R.sub.1, and R.sub.2 are as defined in the specification.Type: GrantFiled: December 16, 1998Date of Patent: August 3, 1999Assignee: Dong Wha Pharm. Ind. Co., Ltd.Inventors: Sung June Yoon, Yong Ho Chung, Moon Sun Lee, Dong Rack Choi, Jung A Lee, Hee Soon Lee, Hae Ran Yun, Dug Keun Lee, Eun Yi Moon, Hyun Sook Hwang, Chung Ha Choi, Sang Hun Jung
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Patent number: 5929103Abstract: The present invention relates to a novel arylsulfonylimidazolone derivative represented by the following formula (I) which shows a superior antineoplastic activity in contrast to the known sulfonylurea antitumor agents as well as little side effect: ##STR1## and its pharmaceutically acceptable salt and stereoisomer, in which ----, R.sub.1, and R.sub.2 are as defined in the specification.Type: GrantFiled: August 21, 1997Date of Patent: July 27, 1999Assignee: Dong Wha Pharm. Ind. Co., Ltd.Inventors: Sung June Yoon, Yong Ho Chung, Moon Sun Lee, Dong Rack Choi, Jung A Lee, Hee Soon Lee, Hae Ran Yun, Dug Keun Lee, Eun Yi Moon, Hyun Sook Hwang, Chung Ha Choi, Sang Hun Jung
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Patent number: 5496947Abstract: The present invention relates to the novel quinolone carboxylic acid derivatives of the following formula (I) and their pharmaceutically acceptable salts and their hydrates. ##STR1## wherein X is a hydrocarbon, fluorocarbon or nitrogen atom,Y is a hydrogen or methyl group,R.sup.1 is a hydrogen or alkyl group having 1 to 5 carbon atom,R.sup.2 is ##STR2## wherein A and B is a fluorocarbon or nitrogen atom, provided that, if A.dbd.CF, B.dbd.N and if A.dbd.N, B.dbd.CF) andR.sup.3 is ##STR3## (wherein R.sup.4 is an amino group which makes a racemate or (S)-enantiomer) or ##STR4## (wherein R.sup.5, R.sup.6 and R.sup.7 are respectively hydrogen or alkyl group having 1 to 3 carbon atom.).The compounds according to the present invention are used as antibacterial agents.Type: GrantFiled: February 8, 1994Date of Patent: March 5, 1996Assignee: Dong Wha Pharmaceutical Industrial Co., Ltd.Inventors: Sung-June Yoon, Young-Ho Chung, Chi-Woo Lee, Yoon-Seok Oh, Dong-Rack Choi, Nam-Doo Kim