Patents by Inventor Sung-Teh Kim
Sung-Teh Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7914681Abstract: According to the present invention, there is provided a hemodiafiltration apparatus capable of easily and efficiently removing medium to large molecule solutes at a low cost. Provided is a hemodialysis apparatus which uses a hemodialyzer accommodating a hollow yarn membrane in hemodiafiltration to cause a dialysis fluid to flow from a dialysis fluid circuit side to a blood circuit side by forceful back-filtration via the hemodialyzer, and to cause a fluid in the blood circuit to reflux to a dialysis fluid circuit side by filtration via the hemodialyzer, the hemodialysis apparatus being characterized in that a flux operation of the fluid from the dialysis fluid side to the blood circuit side by the back-filtration, and a reflux operation of the fluid from the blood circuit side to the dialysis fluid circuit side by the filtration are repeated intermittently and for at least a plurality of times.Type: GrantFiled: May 28, 2004Date of Patent: March 29, 2011Assignee: JMS Co.Inventors: Sung-Teh Kim, Kunihiko Yamanaka, Naritomi Maeda, Katsunori Masaoka
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Publication number: 20100312162Abstract: Provided is a hemodialysis apparatus which can fundamentally solve a problem in that air is trapped in a mesh disposed in a vein side chamber during priming.Type: ApplicationFiled: November 18, 2008Publication date: December 9, 2010Applicant: Kitakyusyu Institute of BiophysicsInventors: Katsunori Masaoka, Kazuo Maehara, Shingo Chiba, Sung-Teh Kim, Chieko Yamamoto
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Patent number: 7780848Abstract: A single needle hemodiafiltration apparatus is provided. The single needle hemodiafiltration apparatus includes circuits for blood supply from a patient and blood return to a patient, a dialysis fluid supply system for supplying a dialysis fluid, and a system for controlling the blood flow and dialysis fluid flow in a separation device which is equipped to perform filtration and back-filtration operations. A controller is provided that controls, in a series of coordinated operations, the flow of blood from the patient into the separation device, the flow of filtration fluid and back filtration fluid, and the return of blood to the patient.Type: GrantFiled: June 18, 2004Date of Patent: August 24, 2010Assignee: JMS Co.Inventors: Sung-Teh Kim, Kunihiko Yamanaka, Naritomi Maeda, Katsunori Masaoka, Kayoko Segawa, Chieko Yamamoto
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Publication number: 20090159515Abstract: According to the present invention, there is provided a hemodiafiltration apparatus capable of easily and efficiently removing medium to large molecule solutes at a low cost. Provided is a hemodialysis apparatus which uses a hemodialyzer accommodating a hollow yarn membrane in hemodiafiltration to cause a dialysis fluid to flow from a dialysis fluid circuit side to a blood circuit side by forceful back-filtration via the hemodialyzer, and to cause a fluid in the blood circuit to reflux to a dialysis fluid circuit side by filtration via the hemodialyzer, the hemodialysis apparatus being characterized in that a flux operation of the fluid from the dialysis fluid side to the blood circuit side by the back-filtration, and a reflux operation of the fluid from the blood circuit side to the dialysis fluid circuit side by the filtration are repeated intermittently and for at least a plurality of times.Type: ApplicationFiled: May 28, 2004Publication date: June 25, 2009Applicant: JMS CO.Inventors: Sung-Teh Kim, Kunihiko Yamanaka, Naritomi Maeda, Katsunori Masaoka
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Patent number: 7441666Abstract: It is intended to provide asymmetric porous films which are usable in blood dialysis, plasma separation, etc. and particularly excellent in the performance of selectively separating (fractionating) plasma protein, show little endogenous coagulation, complement or quinine activily and have an extremely high biocompatibility. Porous films made mainly of a synthetic polymer and having an asymmetric structure wherein, in the sectional structure, a dense layer substantially not charged at least on the outermost surface is provided in the side on which a liquid to be treated is loaded and at least part of the film other than the outermost surface is negatively charged. In the above films, the dense layer non-charged at least on the outermost surface serves as a size barrier while the part of the film other than the outermost surface serves as a charge barrier.Type: GrantFiled: April 18, 2002Date of Patent: October 28, 2008Assignee: Asahi Kasei Kuraray Medical Co., Ltd.Inventors: Sung-Teh Kim, Chieko Yamamoto, Toshinori Koizumi, Masatoshi Saitoh, Shunji Maniwa
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Publication number: 20080251433Abstract: Provided is a hemodialyzer in which deterioration in membrane performance of a hollow fiber with time can be grasped accurately during dialysis and the performance can be recovered quickly and positively. The hemodialyzer, constituted by connecting an artery side blood circuit (2) having a blood pump (7) to the artery side of a dialyzer (1), connecting a vein side blood circuit (3) to the vein side of the dialyzer (1), and connecting a dialysate supply line (4) and a dialysate discharge line (5), respectively, to the side face of the dialyzer (1), is provided with a detector (15) for determining the pressure in the blood circuit, and a detector (16) for determining the pressure in the dialysate line, in which transmembrane pressure is calculated based on the determined pressures, and reverse filtering is performed by the dialyzer (1) when the transmembrane pressure exceeds a predetermined level.Type: ApplicationFiled: March 31, 2006Publication date: October 16, 2008Applicants: JMS CO., KITAKYUSHU INSTITUTE OF BIOPHYSICSInventors: Sung-Teh Kim, Chieko Yamamoto, Kayoko Segawa, Kunihiko Yamanaka, Katsunori Masaoka
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Publication number: 20080156729Abstract: An apparatus for blood dialysis composed at least of a hemodialyzer (a) whereby blood is brought into contact with a dialysate via a semipermeable membrane and thus purified; a blood circulation system (b) composed of a blood circuit in the arterial side whereby blood is taken out from a patient and flown into the hemodialyzer and another blood circuit in the venous side whereby the blood flown out from the hemodialyzer is returned to the patient; a dialysate supplying/discharging system (c) for supplying and discharging the dialysate composed of a dialysate-supply line for supplying the dialysate to the hemodialyzer and a dialysate-discharge line for discharging the dialysate flown out from the hemodialyzer, and a means (d) of controlling the back-filtration speed. Owing to this constitution, individual steps from the preparation of the dialysis (treatment) to the completion of the treatment and the change from a specific step to the next step can be safely, surely and quickly carried out in most cases.Type: ApplicationFiled: September 27, 2007Publication date: July 3, 2008Applicants: JMS CO., LTD, KITAKYUSHU INSTITUTE OF BIOPHYSICS CO., LTD.Inventors: SUNG-TEH KIM, MASAHIRO TAOKA, CHIEKO YAMAMOTO, Kunihiko Yamanaka, KATUNORI MASAOKA
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Patent number: 7285105Abstract: An automatic dialyzer for purifying blood brought into contact with a dialysate via a semi-impermeable membrane. The dialyzer includes at least a blood circulating system and a dialysate supply/discharge system, wherein the blood line of the blood circulating system is connected to an overflow line having a reversibly-rotatable blood pump, a blood chamber, and an open/close device for overflowing of liquid from the blood chamber to the outside of the blood line. Liquid supply means is provided to a first bypass line and/or a second bypass line for supplying liquid in both forward and reverse directions to enable regulation of the supply amount of the dialysate for water removing/liquid replenishing. The supply speed of the liquid supply device and the supply speed of the blood pump are regulatable in conjunction with each other. Also provided is a dialyzing method using the automatic dialyzer.Type: GrantFiled: June 14, 2001Date of Patent: October 23, 2007Assignees: JMS Co., Ltd, KitaKyusha Institute of Biophysics Co., LtdInventors: Sung-Teh Kim, Masahiro Taoka, Tieko Yamamoto, Kunihiko Yamanaka, Katunori Masaoka
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Publication number: 20060138049Abstract: A novel single needle hemodiafiltration apparatus and a novel single needle hemodiafiltration method for purifying blood with excellent removal performance via extracorporeal circulation with a single needle type are provided. The single needle hemodiafiltration apparatus includes a blood supply system for supplying blood, a dialysis fluid supply system for supplying a dialysis fluid and a system for controlling a movement of a fluid between the two supply systems, and a filtration/back-filtration liquid supply unit provided in the dialysis fluid supply system is controlled in conjunction with a blood pump provided in the blood supply system so that blood is removed from the body synchronously with the filtration and returned to the body synchronously with the back-filtration, thereby enabling extracorporeal circulation with the single needle. At a time of filtration, substances are removed by diffusion and ultrafiltration. At a time of recirculation in the blood circuit, substances are removed by diffusion.Type: ApplicationFiled: June 19, 2003Publication date: June 29, 2006Inventors: Sung-Teh Kim, Kunihiko Yamanaka, Naritomi Maeda, Katsunori Masaoka, Kayoko Segawa, Chieko Yamamoto
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Patent number: 6971680Abstract: The present invention provides a dialysis coupler assembly comprising a pair of rubber-like elastic tubular couplers, and a pair of joint members for joining the couplers together. Each of the couplers includes an inner channel 14 allowing a connector associated with a medical device to be fitted therein, and a smooth surface 15, 16 perpendicular to the longitudinal axis of the coupler. The couplers are adapted to be joined together through the joint members in such manner that the smooth surfaces are in liquid-tight contact with one another. Each of the joint members is adapted to be attached slidably and rotatably onto corresponding one of the couplers, the joint members having first and second engagement portions, respectively. The first and second engagement portions are disposed opposed to one another and adapted to cooperatively engage the joint members with one another so as to allow the smooth surfaces to be brought into liquid-tight contact with one another.Type: GrantFiled: March 5, 2003Date of Patent: December 6, 2005Assignees: Kitakyushu Institute of Biophysics Co., Ltd., JMS Co., Ltd.Inventors: Yoshihiko Nakanishi, Kunihiko Yamanaka, Hiromu Miura, Katsunori Masaoka, Takaaki Matsuo, Masahiro Taoka, Sung-Teh Kim
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Publication number: 20050230314Abstract: An apparatus for blood dialysis composed at least of a hemodialyzer (a) whereby blood is brought into contact with a dialysate via a semipermeable membrane and thus purified; a blood circulation system (b) composed of a blood circuit in the arterial side whereby blood is taken out from a patient and flown into the hemodialyzer and another blood circuit in the venous side whereby the blood flown out from the hemodialyzer is returned to the patient; a dialysate supplying/discharging system (c) for supplying and discharging the dialysate composed of a dialysate-supply line for supplying the dialysate to the hemodialyzer and a dialysate-discharge line for discharging the dialysate flown out from the hemodialyzer, and a means (d) of controlling the back-filtration speed. Owing to this constitution, individual steps from the preparation of the dialysis (treatment) to the completion of the treatment and the change from a specific step to the next step can be safely, surely and quickly carried out in most cases.Type: ApplicationFiled: December 18, 2002Publication date: October 20, 2005Applicants: JMS Co., Ltd., Kitakyushu Institute of Biophysics Co., Ltd.Inventors: Sung-Teh Kim, Masahiro Taoka, Chieko Yamamoto, Kunihiko Yamanaka, Katunori Masaoka
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Publication number: 20040173515Abstract: The present invention provides a dialysis coupler assembly comprising a pair of rubber-like elastic tubular couplers, and a pair of joint members for joining the couplers together. Each of the couplers includes an inner channel 14 allowing a connector associated with a medical device to be fitted therein, and a smooth surface 15, 16 perpendicular to the longitudinal axis of the coupler. The couplers are adapted to be joined together through the joint members in such manner that the smooth surfaces are in liquid-tight contact with one another. Each of the joint members is adapted to be attached slidably and rotatably onto corresponding one of the couplers, the joint members having first and second engagement portions, respectively. The first and second engagement portions are disposed opposed to one another and adapted to cooperatively engage the joint members with one another so as to allow the smooth surfaces to be brought into liquid-tight contact with one another.Type: ApplicationFiled: March 5, 2003Publication date: September 9, 2004Inventors: Yoshihiko Nakanishi, Kunihiko Yamanaka, Hiromu Miura, Katsunori Masaoka, Takaaki Matsuo, Masahiro Taoka, Sung-Teh Kim
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Publication number: 20040167237Abstract: It is intended to provide asymmetric porous films which are usable in blood dialysis, plasma separation, etc. and particularly excellent in the performance of selectively separating (fractionating) plasma protein, show little endogenous coagulation, complement or quinine activily and have an extremely high biocompatibility. Porous films made mainly of a synthetic polymer and having an asymmetric structure wherein, in the sectional structure, a dense layer substantially not charged at least on the outermost surface is provided in the side on which a liquid to be treated is loaded and at least part of the film other than the outermost surface is negatively charged. In the above films, the dense layer non-charged at least on the outermost surface serves as a size barrier while the part of the film other than the outermost surface serves as a charge barrier.Type: ApplicationFiled: April 7, 2004Publication date: August 26, 2004Inventors: Sung-Teh Kim, Chieko Yamamoto, Toshinori Koizumi, Masatoshi Saitoh, Shunji Maniwa
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Publication number: 20030163077Abstract: An automatic dialyzer for purifying blood brought into contact with a dialysate via a semi-impermeable membrane, comprising at least a blood circulating system and a dialysate supply/discharge system, characterized in that the blood line of the blood circulating system is connected to an overflow line having a reversibly-rotatable blood pump and also having a blood chamber and an open/close means for overflowing of liquid from the blood chamber to the outside of the blood line, and liquid supply means, for supplying liquid in both forward and reverse directions and being able to regulate the supply amount of the dialysate for water removing/liquid replenishing, are provided to a first bypass line and/or a second bypass line, the supply speed of the liquid supply means and the supply speed of the blood pump being regulatable in conjunction with each other; and a dialyzing method using the automatic dialyzer.Type: ApplicationFiled: March 11, 2003Publication date: August 28, 2003Inventors: Sung-Teh Kim, Masahiro Taoka, Tieko Yamamoto, Kunihiko Yamanaka, Katunori Masaoka