Abstract: Provided are a HNF-1 ? gene including a novel single-nucleotide polymorphism and a protein encoded by the HNF-1 ? gene, a polynucleotide associated with MODY3 diabetes based on the HNF-1 ? gene, a microarray and a diagnostic kit including the polynucleotide, and a method for diagnosis of MODY3 diabetes.

Abstract: Provided is a method for detecting a target nucleic acid, comprising amplifying a target nucleic acid from a nucleic acid sample using a set of primers comprising at least one primer having a tag sequence at its 5? end and a target binding sequence at its 3? end; hybridizing the resulting amplified products with detection probes labeled with a label, the detection probes being capable of specifically binding to the tag sequence; hybridizing the hybridization products with capture probes immobilized on a microarray, the capture probes being capable of specifically binding to the target nucleic acid and not to the tag sequence; and determining the results of hybridization.

Abstract: A primer pool including at least two sets of primers for amplifying at least two target sequences of human MODY gene 1, 4, 5, 6, or 7, the at least two sets of primers being selected from the group consisting of sets of primers, each set including an oligonucleotide having one of SEQ ID NOS. 1 through 32, 41 and 42 and its variant oligonucleotide.