Abstract: A bispecific recombinant protein, comprising a first functional binding fragment, a second functional binding fragment, and an Fc region. The first functional binding fragment targeting an antigen of interest of the bispecific recombinant protein comprises an antigen-binding fragment, wherein the C-terminus of the CL domain or the C-terminus of the CH1 domain in the antigen-binding fragment is directly connected to or is connected via a linker to the second functional binding fragment having the functions of immunoregulation and/or metabolic regulation and/or endocrine regulation. The recombinant protein can improve the targeting for the target of the second functional binding fragment of the bispecific recombinant protein and can also reduce toxic side effects caused by the non-target protein containing the second functional binding fragment generated during the preparation process targeting non-target organs, tissues and cells.

Abstract: Systems and methods for detecting blockages for light detection and ranging (“LiDAR”) devices are disclosed. According to one embodiment, a light detection and ranging (LiDAR) blockage detection method includes emitting, by an active channel of a plurality of channels of a LiDAR device, an optical signal toward a configured position on a housing of the LiDAR device. A passive listening channel of the plurality of channels receives a return signal originating from the optical signal. Based on a comparison of data derived from the return signal and data derive from a reference signal, a determination is made as to whether a blockage is present at the configured position on the housing.

Abstract: The present disclosure relates to an integrated wastewater treatment apparatus and method, the apparatus comprises a first reactor module, a second reactor module, a sedimentation module and a gas-liquid separation module, the first reactor module comprises a first reactor and an anoxic reaction zone, an aerobic reaction zone, a first gas-gathering pressurized layer, a first water inlet pipe and an aeration device; the second reactor module comprises a second reactor, a second water inlet pipe, an anaerobic reaction zone and a second gas-gathering pressurized layer; the sedimentation module comprises a third reactor and a water outlet pipe; the gas-liquid separation module comprises a gas-liquid separator, an exhaust pipe, a first riser pipe, a second riser pipe and a return pipe. The apparatus can give full play to the advantages of the autotrophic biological denitrification process, meet the biochemical treatment requirements of wastewater with low C/N ratio.

Abstract: The present disclosure relates to an integrated wastewater treatment apparatus and method, the apparatus comprises a first reactor module, a second reactor module, a sedimentation module and a gas-liquid separation module, the first reactor module comprises a first reactor and an anoxic reaction zone, an aerobic reaction zone, a first gas-gathering pressurized layer, a first water inlet pipe and an aeration device; the second reactor module comprises a second reactor, a second water inlet pipe, an anaerobic reaction zone and a second gas-gathering pressurized layer; the sedimentation module comprises a third reactor and a water outlet pipe; the gas-liquid separation module comprises a gas-liquid separator, an exhaust pipe, a first riser pipe, a second riser pipe and a return pipe. The apparatus can give full play to the advantages of the autotrophic biological denitrification process, meet the biochemical treatment requirements of wastewater with low C/N ratio.