Abstract: The present invention includes methods, devices, systems, circuits and associated computer executable code for detecting and predicting the position and trajectory of surgical tools. According to some embodiments of the present invention, images of a surgical tool within or in proximity to a patient may be captured by a radiographic imaging system. The images may be processed by associated processing circuitry to determine and predict position, orientation and trajectory of the tool based on 3D models of the tool, geometric calculations and mathematical models describing the movement and deformation of surgical tools within a patient body.