Patents by Inventor Susan G. Fogerite

Susan G. Fogerite has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reconstituting viral glycoproteins into large phospholipid vesicles
    Patent number: 4871488
    Abstract: The present disclosure relates to novel liposome compositions and methods for their preparation. Utilization of the present invention provides an efficient reconstitution of membrane proteins into large (0.1 to 2 micron diameter) phospholipid vesicles with a large, internal aqueous space. The method has been exemplified with the use of glycoproteins of influenza (A/PR8/34) and Sendai (parainfluenza type I) viruses. The method comprises (A) extracting out the desired membrane protein from a source biological material with an extraction buffer comprising a detergent; (B) mixing the extract with a phospholipid solution and deriving a cochleate intermediate; and (C) forming large phospholipid vesicles with integrated membrane protein in a biologically active state.
    Type: Grant
    Filed: April 13, 1987
    Date of Patent: October 3, 1989
    Assignee: Albany Medical College of Union University
    Inventors: Raphael J. Mannino, Susan G. Fogerite
  • Liposome methods and compositions
    Patent number: 4663161
    Abstract: The present disclosure relates to novel liposome compositions and methods for their preparation. Utilization of the present invention provides an efficient reconstitution of membrane proteins into large (0.1 to 2 micron diameter) phospholipid vesicles with a large, internal aqueous space. The method has been exemplified with the use of glycoproteins of influenza (A/PR8/34) and Sendai (parainfluenza type I) viruses.
    Type: Grant
    Filed: April 22, 1985
    Date of Patent: May 5, 1987
    Inventors: Raphael J. Mannino, Susan G. Fogerite