Patents by Inventor Susan J. Baserga

Susan J. Baserga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for increasing tissue oxygenation using fish hemoglobin exhibiting a root effect
    Patent number: 5770560
    Abstract: The invention relates to the use of fish hemoglobins that exhibit a Root effect to increase tissue oxygenation in patients suffering from disease states associated with compromised oxygen delivery to tissues.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: June 23, 1998
    Assignee: James J. Fischer
    Inventors: James J. Fischer, Susan J. Baserga
  • Genetically engineered low oxygen affinity mutants of human hemoglobin
    Patent number: 5428007
    Abstract: Peptides encoded by a substantially pure polynucleotide coding for an alpha and/or beta human globin, the globin when part of a hemoglobin molecule conferring lower oxygen affinity than normal hemoglobin to result in a mutant hemoglobin, the mutant hemoglobin having an oxygen affinity measured for stripped hemoglobin characterized by a P.sub.50 of 30 torr to 3 atmospheres and/or by a Hill coefficient between 2.5 and 1.0. Such mutant hemoglobin being useful to increase tissue oxygenation in a patient, to replace hemoglobin in the bloodstream of a patient and to treat patients suffering from burns.
    Type: Grant
    Filed: April 28, 1994
    Date of Patent: June 27, 1995
    Assignee: Yale University
    Inventors: James J. Fischer, Susan J. Baserga
  • DNAs encoding genetically engineered low oxygen affinity mutants of human hemoglobin
    Patent number: 5173426
    Abstract: A substantially pure polynucleotide coding for an alpha and/or beta human globin, the globin when part of a hemoglobin molecule confering lower oxygen affinity than normal hemoglobin to result in a mutant hemoglobin, the mutant hemoglobin having an oxygen affinity measured for stripped hemoglobin characterized by a P.sub.50 of 30 torr to 3 atmospheres and/or by a Hill coefficient between 2.5 and 1.0. Such mutant hemoglobin being useful to increase tissue oxygenation in a patient, to replace hemoglobin in the bloodstream of a patient and to treat patients suffering from burns.
    Type: Grant
    Filed: October 6, 1989
    Date of Patent: December 22, 1992
    Assignee: Yale University
    Inventors: James J. Fischer, Susan J. Baserga