Patents by Inventor Susi Tan

Susi Tan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanocomplex
    Patent number: 10993917
    Abstract: There is provided a nanocomplex having a core-shell structure. The shell of the nanocomplex comprises a functionalized hyaluronic acid while the core of the nanocomplex comprises a flavonoid encapsulating a metal-containing compound. Preferably, the flavonoid is epigallocatechin gallate (EGCG) and the hyaluronic acid is thiol-functionalized and subsequently conjugated to the flavonoid. There is also provided a method of forming the nanocomplex, a pharmaceutical composition comprising the nanocomplex, medical uses of the nanocomplex and a method of treating a patient, preferably with cancer using the nanocomplex.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: May 4, 2021
    Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Motoichi Kurisawa, Ki Hyun Bae, Susi Tan
  • A NANOCOMPLEX
    Publication number: 20190262271
    Abstract: There is provided a nanocomplex having a core-shell structure. The shell of the nanocomplex comprises a functionalized hyaluronic acid while the core of the nanocomplex comprises a flavonoid encapsulating a metal-containing compound. Preferably, the flavonoid is epigallocatechin gallate (EGCG) and the hyaluronic acid is thiol-functionalized and subsequently conjugated to the flavonoid. There is also provided a method of forming the nanocomplex, a pharmaceutical composition comprising the nanocomplex, medical uses of the nanocomplex and a method of treating a patient, preferably with cancer using the nanocomplex.
    Type: Application
    Filed: December 29, 2017
    Publication date: August 29, 2019
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Motoichi Kurisawa, Ki Hyun Bae, Susi Tan
  • ANTI-CANCER AGENT DELIVERY VEHICLES CAPABLE OF IMPROVED LOADING
    Publication number: 20170258757
    Abstract: There is provided a conjugate of a delivery agent containing a chemical moiety and at least one flavonoid. The flavonoid exists in a monomeric form or dimeric form before conjugation and remains in the monomeric form or dimeric form after conjugation. Preferably, the conjugate comprises two flavonoids. The delivery agent is conjugated at the C6 and/or the C8 position of the A ring of the flavonoid. An anti-cancer agent delivery vehicle comprising an anti-cancer agent and the conjugate is also provided.
    Type: Application
    Filed: May 18, 2017
    Publication date: September 14, 2017
    Inventors: Motoichi Kurisawa, Kun Liang, Susi Tan, Joo Eun Chung, Jackie Y. Ying
  • Anti-cancer agent delivery vehicles capable of improved loading
    Patent number: 9687464
    Abstract: There is provided a conjugate of a delivery agent containing a chemical moiety and at least one flavonoid. The flavonoid exists in a monomeric form or dimeric form before conjugation and remains in the monomeric form or dimeric form after conjugation. Preferably, the conjugate comprises two flavonoids. The delivery agent is conjugated at the C6 and/or the C8 position of the A ring of the flavonoid. An anti-cancer agent delivery vehicle comprising an anti-cancer agent and the conjugate is also provided.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: June 27, 2017
    Assignee: Agency for Science, Technology and Research
    Inventors: Motoichi Kurisawa, Kun Liang, Susi Tan, Joo Eun Chung, Jackie Y. Ying
  • ANTI-CANCER AGENT DELIVERY VEHICLES CAPABLE OF IMPROVED LOADING
    Publication number: 20130004488
    Abstract: There is provided a conjugate of a delivery agent containing a chemical moiety and at least one flavonoid. The flavonoid exists in a monomeric form or dimeric form before conjugation and remains in the monomeric form or dimeric form after conjugation. Preferably, the conjugate comprises two flavonoids. The delivery agent is conjugated at the C6 and/or the C8 position of the A ring of the flavonoid. An anti-cancer agent delivery vehicle comprising an anti-cancer agent and the conjugate is also provided.
    Type: Application
    Filed: March 11, 2011
    Publication date: January 3, 2013
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Motoichi Kurisawa, Kun Liang, Susi Tan, Joo Eun Chung, Jackie Y. Ying