Abstract: The present invention provides a microbubble washing apparatus for washing the pubic region and the like using a washing agent composition containing a protease and a lipase, and a washing liquid containing microbubbles and a microbubble washing method using the washing apparatus. The microbubble washing apparatus includes a microbubble generation mechanism configured to prepare washing liquid containing microbubbles, a nozzle configured to discharge the prepared washing liquid, and a washing liquid holding section attachable to cover the pubic region and the like and configured to seal and hold the washing liquid discharged from the nozzle such that the washing liquid does not leak outside. The washing liquid holding section has a washing liquid inlet to introduce the washing liquid discharged from the nozzle into the washing liquid holding section and a washing liquid outlet to eject the introduced washing liquid.

Abstract: A cell culture method and a cell culture device used with the cell culture method allow mass-producing a three-layer blood-brain barrier (BBB) in vitro model including a vascular endothelial cell, a pericyte, and an astrocyte. A cell culture method enhances mass production of the three-layer BBB models. A cell culture method includes injecting a suspended cell culture medium into an outer surface of a porous membrane in a cell culture insert, seeding the cell culture medium with an astrocyte to culture the astrocyte, seeding the cell culture insert being inverted with a pericyte to culture the pericyte, seeding the cell culture insert with a temperature-sensitive vascular endothelial cell embedded in a temperature-sensitive gel to culture the vascular endothelial cell, and melting the temperature-sensitive gel.

Abstract: A braided hair washing method includes washing braided hair using a washing agent that includes a microbubble washing composition and microbubbles, the microbubble washing composition including a protease and a lipase. The braided hair washing method can conveniently and effectively wash braided hair without collapsing the hairstyle.

Abstract: A nozzle for generating microbubbles includes a nozzle main body provided with a water introduction port for introducing pressurized hot water from the bottom center of the nozzle main body into the main body. A core cylinder provided with an opening in a circumferential face is inserted into the nozzle main body to form a throttle part between an edge part of the bottom outer circumference of the core cylinder and an edge part of the bottom inner circumference of the nozzle main body. A gripper is provided for pulling the core cylinder in the direction opposite to the inserting direction. Hot water passed through the throttle part is introduced into the inner part of the core cylinder through the opening of the circumferential face of the core cylinder and hot water in which microbubbles are generated is ejected to the outside.

Abstract: The present invention provides a microbubble washing composition for washing a human body or an animal, a microbubble washing method using the microbubble washing composition, and a microbubble washing apparatus suitable for carrying out the method are provided which are capable of safely removing sebum and old keratin adhering to the surfaces of the pores in a short period of time, keeping the skin clean for a long period of time, preventing an odor. Specifically, the present invention provides a microbubble washing composition for washing a human body or an animal including a protease and a lipase, a microbubble washing method for washing a human body or an animal including washing a human body or an animal using a washing liquid containing the washing composition and microbubbles, and a microbubble washing apparatus.

Abstract: In conventional nozzles, small holes provided for an orifice correspond to a throttle part, and, when the nozzle is used for cleaning, in particular, when hot water containing a cleaning agent is circulated, if the removal of foreign particles gotten into the hot water is insufficient, the foreign particle might clog the small hole to block it up. The blockage of only one to two small holes largely influences the condition of generating microbubbles to result in insufficient generation of microbubbles.

Abstract: A hair growth method includes repeatedly washing hair using a washing agent that includes a microbubble washing composition and microbubbles, the microbubble washing composition including a protease and a lipase. The hair growth method exhibits an excellent hair growth effect.

Abstract: A braided hair washing method includes washing braided hair using a washing agent that includes a microbubble washing composition and microbubbles, the microbubble washing composition including a protease and a lipase. The braided hair washing method can conveniently and effectively wash braided hair without collapsing the hairstyle.

Abstract: A washing device for washing a portion of a user's head includes a discharge section which discharges a cleaning liquid into a washing cap attached to a portion of a user's head, and a recovery section which drains the cleaning liquid out of the washing cap so as to recover it. The device again discharges the cleaning liquid recovered by the recovery section from the discharge section, and recirculates the cleaning liquid so as to wash the portion of the user's head covered by the washing cap. When the cleaning liquid is dispersed into the washing cap, the cleaning liquid passes through a nozzle unit so that a lot of microbubbles are generated in the cleaning liquid. The microbubbles are very fine air bubbles, and can remove fine particles of dirt down to the order of a few microns but do not damage the user's scalp and hair.

Abstract: In a scalp washing device a droplet preventing plate is provided positioned between a user's scalp and face, a nozzle having a single discharge port which discharges hot water to the scalp side of the droplet preventing plate is disposed, and hot water discharged from the discharge port of the nozzle is dispersed along the droplet preventing plate so as to be supplied to the user's scalp. For this reason, the flow rate of the hot water is reduced during the dispersion along the droplet preventing plate, and at the time when the hot water is separated from the edge of the droplet preventing plate and is supplied to the user's scalp, the hot water is supplied slowly to the entire scalp, and droplets are not generated. Even if a small gap is generated between the droplet preventing plate and the user's face, the droplets do not leak to the user's face, wetting it.

Abstract: The present invention provides a microbubble washing composition for washing a human body or an animal, a microbubble washing method using the microbubble washing composition, and a microbubble washing apparatus suitable for carrying out the method are provided which are capable of safely removing sebum and old keratin adhering to the surfaces of the pores in a short period of time, keeping the skin clean for a long period of time, preventing an odor. Specifically, the present invention provides a microbubble washing composition for washing a human body or an animal including a protease and a lipase, a microbubble washing method for washing a human body or an animal including washing a human body or an animal using a washing liquid containing the washing composition and microbubbles, and a microbubble washing apparatus.

Abstract: The present invention provides a microbubble washing composition for washing a human body or an animal, a microbubble washing method using the microbubble washing composition, and a microbubble washing apparatus suitable for carrying out the method are provided which are capable of safely removing sebum and old keratin adhering to the surfaces of the pores in a short period of time, keeping the skin clean for a long period of time, preventing an odor. Specifically, the present invention provides a microbubble washing composition for washing a human body or an animal including a protease and a lipase, a microbubble washing method for washing a human body or an animal including washing a human body or an animal using a washing liquid containing the washing composition and microbubbles, and a microbubble washing apparatus.

Abstract: A washing device for washing a portion of a user's head includes a discharge section which discharges a cleaning liquid into a washing cap attached to a portion of a user's head, and a recovery section which drains the cleaning liquid out of the washing cap so as to recover it. The device again discharges the cleaning liquid recovered by the recovery section from the discharge section, and recirculates the cleaning liquid so as to wash the portion of the user's head covered by the washing cap. When the cleaning liquid is dispersed into the washing cap, the cleaning liquid passes through a nozzle unit so that a lot of microbubbles are generated in the cleaning liquid. The microbubbles are very fine air bubbles, and can remove fine particles of dirt down to the order of a few microns but do not damage the user's scalp and hair.

Abstract: In a scalp washing device of the present invention, a droplet preventing plate is provided positioned between a user's scalp and face, a nozzle having a single discharge port which discharges hot water to the scalp side of the droplet preventing plate is disposed, and hot water discharged from the discharge port of the nozzle is dispersed along the droplet preventing plate so as to be supplied to the user's scalp. For this reason, the flow rate of the hot water is reduced during the dispersion along the droplet preventing plate, and at the time when the hot water is separated from the edge of the droplet preventing plate and is supplied to the user's scalp, the hot water is supplied slowly to the entire scalp, and droplets are not generated. Even if a small gap is generated between the droplet preventing plate and the user's face, the droplets do not leak to the user's face, wetting it.

Abstract: The present invention provides a microbubble washing composition for washing a human body or an animal, a microbubble washing method using the microbubble washing composition, and a microbubble washing apparatus suitable for carrying out the method are provided which are capable of safely removing sebum and old keratin adhering to the surfaces of the pores in a short period of time, keeping the skin clean for a long period of time, preventing an odor. Specifically, the present invention provides a microbubble washing composition for washing a human body or an animal including a protease and a lipase, a microbubble washing method for washing a human body or an animal including washing a human body or an animal using a washing liquid containing the washing composition and microbubbles, and a microbubble washing apparatus.

Abstract: A white blood cell-removing device has a bag-shaped housing made of soft resin, a white blood cell-removing filter member partitioning the inside of the housing into an inlet side blood chamber and an outlet side blood chamber, a blood inlet port positioned at one side of the housing and communicating with the inlet side blood chamber; and a blood outlet port positioned at the other side of the housing and communicating with the outlet side blood chamber. An inner surface (the outlet side blood chamber) of the bag-shaped housing is a unevenness surface. The white blood cell-removing filter member has a filtering part and a non-filtering part formed on the entire periphery of the filtering part.

Abstract: An apparatus for extracting liquids different in kind from a flexible primary container storing therein liquid components fractionated into three layers to some satellite containers, by virtue of forming a adhering portion inside the primary container, and communicating with a first outlet and a second outlet, and guiding the upper liquid component to either outlets and the lower liquid component to the remaining outlet.

Abstract: A solution separating apparatus has a container holding portion, a container pressurizing portion, an interface detecting portion, and a control unit. The interface detecting portion comprises a light emitting apparatus disposed to one side and a light receiving apparatus disposed to another side with a container held by the container holding portion sandwiched therebetween. The light emitting element comprises a plurality (three or more) of light emitting elements disposed in parallel in the substantially moving direction of the interface within the container. Another solution separating apparatus embodiment has a container holding portion, a tube clamper, a container pressurizing portion, a control unit, and a weight measuring portion commonly used by two or more container holding portions. The weight measuring portion selectively measures the quantity of weight change of each container held by the container holding portions.

Abstract: A liquid separator for use as a blood component separator separates a blood component such as blood plasma from centrifugally separated component layers in a flexible blood bag. The blood bag has a liquid discharge tube on its upper end. The liquid separator includes a container holder for holding the blood bag with the liquid discharge tube directed substantially upwardly, and a container presser for pressing the blood bag progressively from the upper end toward a lower end thereof in coaction with the container holder to force the blood component out of the blood bag through the liquid discharge tube. While the blood bag is pressed, a certain thickness is provided at its upper end to allow the blood component to flow out of the blood back through the blood discharge tube.