Patents by Inventor Susumu Koizumi
Susumu Koizumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240156879Abstract: The present invention relates to a composition which contains an intestinal bacterium belonging to the genus Veillonella and having an inflammation reducing activity, or a substance derived from the intestinal bacterium and having an inflammation reducing activity and which has at least one activity selected from an anti-inflammatory activity, an immunoregulation activity, an epithelial barrier restoring activity, an IL-10-inducing activity, and an IL-22-inducing activity, and to an ameliorating agent for an inflammatory disease, an autoimmune disease, or an infectious disease containing the intestinal bacterium and the substance derived from the intestinal bacterium and having an inflammation reducing activity.Type: ApplicationFiled: March 8, 2022Publication date: May 16, 2024Applicants: JUNTENDO EDUCATIONAL FOUNDATION, Kyowa Kirin Co., Ltd., KYOWA HAKKO BIO CO., LTD.Inventors: Dai ISHIKAWA, Satoshi KOIZUMI, Makoto YAMASHITA, Fuhito YAMAZAKI, Nakayuki HONMA, Itaru URAKAWA, Susumu IWAMOTO
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Patent number: 11981644Abstract: Provided herein are compounds of formula (1): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein X1, X2, Ry, Rz, R1, R2, R3, and R4 are as defined herein. Also provided herein is a pharmaceutically acceptable composition comprising a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided herein are methods of using a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, to treat various diseases, disorders, and conditions responsive to the modulation of the contractility of the skeletal sarcomere.Type: GrantFiled: November 5, 2021Date of Patent: May 14, 2024Assignee: CYTOKINETICS, INC.Inventors: Bradley P. Morgan, Chris Evans, Pu-Ping Lu, Makoto Yamasaki, Wenyue Wang, Scott Collibee, Takuya Makino, Kazuyuki Tsuchiya, Toshio Kurosaki, Susumu Yamaki, Eriko Honjo, Yuka Koizumi, Naoto Katoh, Ryuichi Sekioka, Ikumi Kuriwaki
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Publication number: 20240148799Abstract: The present invention relates to a composition which contains an intestinal bacterium belonging to Bacteroidetes and having an inflammation reducing activity, or a substance derived from the intestinal bacterium and having an inflammation reducing activity and which has at least one activity selected from an anti-inflammatory activity, an immunoregulation activity, an epithelial barrier restoring activity, an IL-10-inducing activity, and an IL-22-inducing activity, and to an ameliorating agent for an inflammatory disease, an autoimmune disease, or an infectious disease containing the intestinal bacterium and the substance derived from the intestinal bacterium and having an inflammation reducing activity.Type: ApplicationFiled: March 8, 2022Publication date: May 9, 2024Applicants: JUNTENDO EDUCATIONAL FOUNDATION, Kyowa Kirin Co., Ltd., KYOWA HAKKO BIO CO., LTD.Inventors: Dai ISHIKAWA, Satoshi KOIZUMI, Makoto YAMASHITA, Fuhito YAMAZAKI, Mikiro HAYASHI, Nakayuki HONMA, Itaru URAKAWA, Susumu IWAMOTO
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Patent number: 10606203Abstract: In accordance with an embodiment, an image forming apparatus comprises a conveyance section configured to convey a print medium; a processing unit configured to form a toner image; an image holding member configured to move the toner image formed by the processing unit; a photoelectric sensor facing the image holding member and of which a detection direction intersects with a conveyance plane on which the print medium is conveyed; and a processor configured to determine passage of the print medium based on the detection result of the photoelectric sensor, and to determine whether or not a density of the toner image formed by the processing unit is a preset density.Type: GrantFiled: November 27, 2018Date of Patent: March 31, 2020Assignee: TOSHIBA TEC KABUSHIKI KAISHAInventor: Susumu Koizumi
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Patent number: 9971277Abstract: An image forming apparatus comprising a developing agent storage section including a discharge port for discharging the developing agent; a developing agent mixer configured inside the developing agent storage section to stir the developing agent and move the developing agent towards the discharge port; a motor which rotates at least the developing agent mixer; a motor control section which rotates the motor at either a first speed at which the developing agent is not discharged from the discharge port or a second speed higher than the first speed to discharge the developing agent from the discharge port; and a device control section which controls the motor control section to switch the rotation speed of the motor to the second speed at a timing different from the timing when the developing roller develops the electrostatic latent image.Type: GrantFiled: November 10, 2016Date of Patent: May 15, 2018Assignees: KABUSHIKI KAISHA TOSHIBA, TOSHIBA TEC KABUSHIKI KAISHAInventor: Susumu Koizumi
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Patent number: 9853269Abstract: An electrical insulation layer including microparticles and having a mesoporous structure; and a battery device including a cathode, an anode, an electrical insulation layer including microparticles and having a mesoporous structure, the electrical insulation layer being arranged between the anode and the cathode, and an ion conductive composition.Type: GrantFiled: December 1, 2014Date of Patent: December 26, 2017Assignees: SEKISUI CHEMICAL CO., LTD., THE UNIVERSITY OF MASSACHUSETTSInventors: Yuying Tang, James Watkins, Kenichi Shinmei, Rasika Dasanayake Aluthge, Susumu Koizumi, Masashi Kanoh
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Patent number: 9846395Abstract: According to one embodiment, an image forming apparatus includes an intermediate transfer belt, multiple first type photoconductive drums, multiple first type transfer rollers, a second type photoconductive drum, a second type transfer roller, a roller, and a roller moving unit. The multiple first type transfer rollers are arranged at positions that face the multiple first type photoconductive drums. The second type photoconductive drum is arranged at a position where the drum surface of the second type photoconductive drum is not tangent to a common tangent plane. The roller is arranged on the inner peripheral side of the intermediate transfer belt and is arranged between the second type transfer roller and one first type transfer roller. The roller moving unit moves the roller by pressing the roller. The roller moving unit changes the state of abutting of the multiple first type photoconductive drums and the second type photoconductive drum.Type: GrantFiled: June 22, 2017Date of Patent: December 19, 2017Assignees: KABUSHIKI KAISHA TOSHIBA, TOSHIBA TEC KABUSHIKI KAISHAInventor: Susumu Koizumi
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Publication number: 20170331096Abstract: An electrical insulation layer including microparticles and having a mesoporous structure; and a battery device including a cathode, an anode, an electrical insulation layer including microparticles and having a mesoporous structure, the electrical insulation layer being arranged between the anode and the cathode, and an ion conductive composition.Type: ApplicationFiled: July 31, 2017Publication date: November 16, 2017Applicants: SEKISUI CHEMICAL CO., LTD., UNIVERSITY OF MASSACHUSETTSInventors: Yuying TANG, James WATKINS, Kenichi SHINMEI, Rasika DASANAYAKE ALUTHGE, Susumu KOIZUMI, Masashi KANOH
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Publication number: 20170285535Abstract: According to one embodiment, an image forming apparatus includes an intermediate transfer belt, multiple first type photoconductive drums, multiple first type transfer rollers, a second type photoconductive drum, a second type transfer roller, a roller, and a roller moving unit. The multiple first type transfer rollers are arranged at positions that face the multiple first type photoconductive drums. The second type photoconductive drum is arranged at a position where the drum surface of the second type photoconductive drum is not tangent to a common tangent plane. The roller is arranged on the inner peripheral side of the intermediate transfer belt and is arranged between the second type transfer roller and one first type transfer roller. The roller moving unit moves the roller by pressing the roller. The roller moving unit changes the state of abutting of the multiple first type photoconductive drums and the second type photoconductive drum.Type: ApplicationFiled: June 22, 2017Publication date: October 5, 2017Inventor: Susumu Koizumi
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Patent number: 9720351Abstract: According to one embodiment, an image forming apparatus includes an intermediate transfer belt, multiple first type photoconductive drums, multiple first type transfer rollers, a second type photoconductive drum, a second type transfer roller, a roller, and a roller moving unit. The multiple first type transfer rollers are arranged at positions that face the multiple first type photoconductive drums. The second type photoconductive drum is arranged at a position where the drum surface of the second type photoconductive drum is not tangent to a common tangent plane. The roller is arranged on the inner peripheral side of the intermediate transfer belt and is arranged between the second type transfer roller and one first type transfer roller. The roller moving unit moves the roller by pressing the roller. The roller moving unit changes the state of abutting of the multiple first type photoconductive drums and the second type photoconductive drum.Type: GrantFiled: September 17, 2015Date of Patent: August 1, 2017Assignees: KABUSHIKI KAISHA TOSHIBA, TOSHIBA TEC KABUSHIKI KAISHAInventor: Susumu Koizumi
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Publication number: 20170082954Abstract: According to one embodiment, an image forming apparatus includes an intermediate transfer belt, multiple first type photoconductive drums, multiple first type transfer rollers, a second type photoconductive drum, a second type transfer roller, a roller, and a roller moving unit. The multiple first type transfer rollers are arranged at positions that face the multiple first type photoconductive drums. The second type photoconductive drum is arranged at a position where the drum surface of the second type photoconductive drum is not tangent to a common tangent plane. The roller is arranged on the inner peripheral side of the intermediate transfer belt and is arranged between the second type transfer roller and one first type transfer roller. The roller moving unit moves the roller by pressing the roller. The roller moving unit changes the state of abutting of the multiple first type photoconductive drums and the second type photoconductive drum.Type: ApplicationFiled: September 17, 2015Publication date: March 23, 2017Inventor: Susumu Koizumi
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Publication number: 20170060030Abstract: An image forming apparatus comprising a developing agent storage section including a discharge port for discharging the developing agent; a developing agent mixer configured inside the developing agent storage section to stir the developing agent and move the developing agent towards the discharge port; a motor which rotates at least the developing agent mixer; a motor control section which rotates the motor at either a first speed at which the developing agent is not discharged from the discharge port or a second speed higher than the first speed to discharge the developing agent from the discharge port; and a device control section which controls the motor control section to switch the rotation speed of the motor to the second speed at a timing different from the timing when the developing roller develops the electrostatic latent image.Type: ApplicationFiled: November 10, 2016Publication date: March 2, 2017Inventor: Susumu Koizumi
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Patent number: 9523941Abstract: An image forming apparatus comprising a developing agent storage section including a discharge port for discharging the developing agent; a developing agent mixer configured inside the developing agent storage section to stir the developing agent and move the developing agent towards the discharge port; a motor which rotates at least the developing agent mixer; a motor control section which rotates the motor at either a first speed at which the developing agent is not discharged from the discharge port or a second speed higher than the first speed to discharge the developing agent from the discharge port; and a device control section which controls the motor control section to switch the rotation speed of the motor to the second speed at a timing different from the timing when the developing roller develops the electrostatic latent image.Type: GrantFiled: May 14, 2015Date of Patent: December 20, 2016Assignees: KABUSHIKI KAISHA TOSHIBA, TOSHIBA TEC KABUSHIKI KAISHAInventor: Susumu Koizumi
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Publication number: 20160334735Abstract: An image forming apparatus comprising a developing agent storage section including a discharge port for discharging the developing agent; a developing agent mixer configured inside the developing agent storage section to stir the developing agent and move the developing agent towards the discharge port; a motor which rotates at least the developing agent mixer; a motor control section which rotates the motor at either a first speed at which the developing agent is not discharged from the discharge port or a second speed higher than the first speed to discharge the developing agent from the discharge port; and a device control section which controls the motor control section to switch the rotation speed of the motor to the second speed at a timing different from the timing when the developing roller develops the electrostatic latent image.Type: ApplicationFiled: May 14, 2015Publication date: November 17, 2016Inventor: Susumu Koizumi
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Publication number: 20150155538Abstract: An electrical insulation layer including microparticles and having a mesoporous structure; and a battery device including a cathode, an anode, an electrical insulation layer including microparticles and having a mesoporous structure, the electrical insulation layer being arranged between the anode and the cathode, and an ion conductive composition.Type: ApplicationFiled: December 1, 2014Publication date: June 4, 2015Applicants: SEKISUI CHEMICAL CO., LTD., UNIVERSITY OF MASSACHUSETTS AMHERSTInventors: Yuying TANG, James WATKINS, Kenichi SHINMEI, Rasika DASANAYAKE ALUTHGE, Susumu KOIZUMI, Masashi KANOH
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Patent number: 8182389Abstract: A technique that makes it possible to switch high-torque power transmission with a compact and simple configuration is provided. A driving force transmitting device that transmits driving force received by one of a first rotating body and a second rotating body to the other includes: the first rotating body; a first engaging section that is provided in the first rotating body; the second rotating body that rotates around a rotating shaft the same as that of the first rotating body; elastically deforming sections that are arranged in the second rotating body; and a second engaging section that is provided in the second rotating body and elastically supported by the elastically deforming sections to engage with the first engaging section and is disengaged from the first engaging section by centrifugal force involved in the rotation of the second rotating body.Type: GrantFiled: February 3, 2009Date of Patent: May 22, 2012Assignees: Kabushiki Kaisha Toshiba, Toshiba Tec Kabushiki KaishaInventor: Susumu Koizumi
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Patent number: 8145089Abstract: A technique of easily detaching a cleaner with a simple configuration is provided. At the time of drawing out a drawing unit, an elastic supporting section is allowed to move against the pressing force of the elastic supporting section to a position where the elastic supporting of the cleaner is released by a support releasing section.Type: GrantFiled: February 3, 2009Date of Patent: March 27, 2012Assignees: Kabushiki Kaisha Toshiba, Toshiba Tec Kabushiki KaishaInventor: Susumu Koizumi
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Publication number: 20110262163Abstract: According to one embodiment, a conveying mechanism including a visualizing agent image carrying mechanism configured to move visualizing agent image, which moves to sheet, to a moving position to sheet, a conveying mechanism configured to move sheet to the moving position where visualizing agent image moves to sheet, a visualizing agent image detector configured to detect the visualizing agent image moved by the visualizing agent image carrying mechanism, a media detector configured to detect passage of sheet to be capable of calculating moving speed of sheet, and a setting unit configured to set, if size of a shift of relative positions of visualizing agent image and sheet exceeds a tolerance, at least one of speed of the visualizing agent image carrying mechanism carries the visualizing agent image and speed of the conveying mechanism moves sheet to an optimum value.Type: ApplicationFiled: April 8, 2011Publication date: October 27, 2011Applicants: Toshiba Tec Kabushiki Kaisha, Kabushiki Kaisha ToshibaInventor: Susumu Koizumi
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Publication number: 20110262152Abstract: According to one embodiment, a sheet conveying mechanism including a first driving mechanism configured to move a sheet medium to a predetermined position, a second driving mechanism located a fixed distance apart from the first driving mechanism and configured to move the sheet medium to the first driving mechanism, a thickness detecting mechanism located between the first driving mechanism and the second driving mechanism and configured to determine thickness of the sheet medium moving between the driving mechanisms, and a controller configured to change, on the basis of the thickness of the sheet medium detected by the thickness detecting mechanism, start of the first driving mechanism and change a movement amount per unit time of the second driving mechanism.Type: ApplicationFiled: April 19, 2011Publication date: October 27, 2011Applicants: Toshiba Tec Kabushiki Kaisha, Kabushiki Kaisha ToshibaInventor: Susumu Koizumi
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Publication number: 20110069327Abstract: According to one embodiment, a printer including, an image carrier configured to hold an a first color image and a second color image in a state in which the images overlap each other and configured to move the overlapping the first color image and the second color image to a sheet in a transfer position, and a controller configured to change speed of forming the first color image and the second color image from a first speed to a second speed higher than the first speed when the thickness of the sheet exceeds a threshold, the first speed including speed obtained by correcting fluctuation in the speed due to the thickness of the sheet with respect to the second speed.Type: ApplicationFiled: September 21, 2010Publication date: March 24, 2011Applicants: Kabushiki Kaisha Toshiba, Toshiba Tec Kabushiki KaishaInventor: Susumu KOIZUMI