Patents by Inventor Susumu Satoh
Susumu Satoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11898155Abstract: Provided is a method for introducing a selected molecule, including: an inhibitor treatment step of allowing a target cell or a target tissue to internalizing an inhibitor of vesicular transport or lysosomal membrane fusion; and an introduction step of contacting an introduction liquid containing a selected molecule with the target cell or the target tissue to introduce the selected molecule into the target cell or the target tissue.Type: GrantFiled: December 6, 2018Date of Patent: February 13, 2024Assignees: PEARL KOGYO CO., LTD., I-GENE CORPORATION, NATIONAL UNIVERSITY CORPORATION EHIME UNIVERSITYInventors: Masafumi Jinno, Yuki Isozaki, Yuto Kikuchi, Yugo Kido, Susumu Satoh
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Publication number: 20210269809Abstract: Provided is a method for producing transformed cells, comprising an introduction step of contacting an introduction liquid comprising a molecule of interest with a target cell to introduce the molecule of interest into the target cell, wherein, in the introduction step, the molecule of interest is introduced via endocytosis into the target cell, a trait is conferred, deleted, or maintained by the introduction of the molecule of interest, and the molecule of interest such as a vector added exogenously does not then remain in an established cell.Type: ApplicationFiled: June 18, 2019Publication date: September 2, 2021Inventors: Masafumi JINNO, Hidemasa KATO, Yoshimi TOKUZAWA, Akihito ONISHI, Junko MYOJO, Susumu SATOH
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Publication number: 20210180088Abstract: Provided is a method for introducing a selected molecule, including: an inhibitor treatment step of allowing a target cell or a target tissue to internalizing an inhibitor of vesicular transport or lysosomal membrane fusion; and an introduction step of contacting an introduction liquid containing a selected molecule with the target cell or the target tissue to introduce the selected molecule into the target cell or the target tissue.Type: ApplicationFiled: December 6, 2018Publication date: June 17, 2021Applicants: Pearl Kogyo Co., Ltd., i-Gene Corporation, National University Corporation Ehime UniversityInventors: Masafumi Jinno, Yuki Isozaki, Yuto Kikuchi, Yugo Kido, Susumu Satoh
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Publication number: 20100196553Abstract: The purpose of the present invention is to provide a coating composition for bakery food products, which coating composition is capable of offering a variety of flavors, has superior moisture-retaining property, the coating composition being pleasantly mild, smooth and flexible and in the form of gel; as well as a bakery food product coated with the coating composition. The above problem is solved by the coating composition for bakery food products of the present invention, said coating composition comprising agar, a saccharide, a modified starch and water, which coating composition is in the form of gel.Type: ApplicationFiled: February 1, 2010Publication date: August 5, 2010Applicant: Matsutani Chemical Industry Co., Ltd.Inventor: Susumu SATOH
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Publication number: 20090036492Abstract: The present invention relates to a novel cercosporamide derivative, a pharmacologically acceptable salt thereof or an ester thereof which has an excellent hypoglycemic effect and is useful as a therapeutic and/or prophylactic agent for diabetes.Type: ApplicationFiled: August 8, 2006Publication date: February 5, 2009Inventors: Akihiro Furukawa, Jun Ohsumi, Tsuyoshi Arita, Takehiro Fukuzaki, Kazushi Araki, Makoto Mori, Takayuki Momose, Takeshi Honda, Masanori Kuroha, Ryo Okuyama, Susumu Satoh
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Patent number: 7402406Abstract: The present invention identified OVARC1000473 (SEQ ID NO: 1) and NT2RM1000377 (SEQ ID NO: 3) as clones showing suppression of CREB activation by forskolin, and provides evaluation methods using these genes, and/or proteins encoded by these genes. Furthermore, these proteins were found to enhance cell damage. Compounds that can be screened based on the evaluation methods of this invention are useful as agents for inhibiting the CREB dephosphorylation reaction, agents for suppressing enhancement of cell damage, and preventive and therapeutic agents for memory disorders and/or neurodegenerative disorders.Type: GrantFiled: October 31, 2002Date of Patent: July 22, 2008Assignee: Astellas Pharma Inc.Inventors: Masahiko Morita, Hiroyuki Arakawa, Mayako Yamazaki, Susumu Satoh, Shintaro Nishimura, Yasuhiro Kita, Takao Yamazaki
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Patent number: 7341864Abstract: A molecule introducing apparatus is provided with a power supply circuit 20 for supplying power, a step-up transformer 30 which is supplied with power from the power supply circuit 20 and which outputs a high voltage, a switching transistor 22 that blocks off and allows the supply of power from the power supply circuit 20 to the step-up transformer 30 and which generates an instantaneous high voltage, and a pair of electrode probes 50 for applying the instantaneous high voltage generated at the step-up transformer 30 to a predetermined region in a body. The molecule introducing apparatus oscillates DNA arranged outside a cell by the instantaneous high voltage so as to introduce the DNA into the cell.Type: GrantFiled: January 29, 2001Date of Patent: March 11, 2008Assignees: The Hollenniun Laboratories, Meiryo Technica Corporation, Ltd.Inventors: Yoshitaka Sakamoto, Masafumi Koide, Juichiro Nakashima, Susumu Satoh, Sousuke Miyoshi, Akiko Suzuki, Hiroyuki Arakawa, Hiroshi Marusawa
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Patent number: 7029860Abstract: The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-? protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-? protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-? protein.Type: GrantFiled: December 17, 2004Date of Patent: April 18, 2006Assignee: Fujisawa Pharmaceutical Co., Ltd.Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Yuri Hio, Mayako Yamazaki, Susumu Satoh, Hiroyuki Arakawa, Masahiko Morita
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Patent number: 6960435Abstract: The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-? protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-? protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-? protein.Type: GrantFiled: July 6, 2000Date of Patent: November 1, 2005Assignee: Fujisawa Pharmaceutical Co., Ltd.Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Yuri Hio, Mayako Yamazaki, Susumu Satoh, Hiroyuki Arakawa, Masahiko Morita
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Publication number: 20050214888Abstract: The present invention identified OVARC1000473 (SEQ ID NO: 1) and NT2RM1000377 (SEQ ID NO: 3) as clones showing suppression of CREB activation by forskolin, and provides evaluation methods using these genes, and/or proteins encoded by these genes. Furthermore, these proteins were found to enhance cell damage. Compounds that can be screened based on the evaluation methods of this invention are useful as agents for inhibiting the CREB dephosphorylation reaction, agents for suppressing enhancement of cell damage, and preventive and therapeutic agents for memory disorders and/or neurodegenerative disorders.Type: ApplicationFiled: October 31, 2002Publication date: September 29, 2005Inventors: Masahiko Morita, Hiroyuki Arakawa, Mayako Yamazaki, Susumu Satoh, Shintaro Nishimura, Yasuhiro Kita, Takao Yamazaki
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Publication number: 20050214813Abstract: The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-? protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-? protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-? protein.Type: ApplicationFiled: December 17, 2004Publication date: September 29, 2005Applicant: Fujisawa Pharmaceutical Co. Ltd.Inventors: Toshio Ota, Takao Isogai, Tetsuo Nishikawa, Yuri Hio, Mayako Yamazaki, Susumu Satoh, Hiroyuki Arakawa, Masahiko Morita
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Patent number: 6884388Abstract: A martensitic stainless steel sheet which is hard to be softened by tempering caused by heating during the use of a disk brake, can maintain the predetermined hardness, and has excellent punching workability, bending workability before quenching, and a particularly small shear drop, and in which a predetermined hardness after quenching is constantly achieved, in a low carbon martensitic stainless steel sheet used only after quenching. Specifically, the sheet contains, on the basis of mass percent, 0.030% to 0.100% C; 0.50% or less of Si; 1.00% to 2.50% Mn; more than 10.00% to 15.00% Cr; at least one selected from the group consisting of 0.01% to 0.50% Ti, 0.01% to 0.50% V, 0.01% to 1.00% Nb, and 0.01% to 1.00% Zr; N in an amount defined by the following expression, N: 0.005% to (Ti+V)×14/50+(Nb+Zr)×14/90; and the balance being Fe and incidental impurities.Type: GrantFiled: August 31, 2001Date of Patent: April 26, 2005Assignee: JFE Steel CorporationInventors: Yoshihiro Ozaki, Toshimitsu Nagaya, Atsushi Miyazaki, Susumu Satoh, Mineo Muraki, Setsuo Kakihara, Toshihiro Kasamo
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Patent number: 6835466Abstract: An alloyed hot-dip galvanized steel sheet is obtained by forming a hot-dip galvanized layer on the surface of the steel sheet and then alloying the steel sheet. The steel sheet exhibits a potential of −850 mV or less when it is immersed in a zinc sulfate-sodium chloride electrolyte. Alternatively, when it is electrolyzed according to constant potential electrolysis process in a zinc sulfate-sodium chloride electrolyte at a potential in a range from −940 mV to −920 mV, the quantity of electricity consumed is less than or equal to 0.5 C/cm2. The steel sheet exhibits excellent processability and particularly excellent sliding property.Type: GrantFiled: December 17, 2002Date of Patent: December 28, 2004Assignee: JFE Steel CorporationInventors: Kyoko Fujimoto, Makoto Shimura, Yoichi Tobiyama, Susumu Satoh
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Publication number: 20040096352Abstract: The present invention provides a martensitic stainless steel sheet which is hard to be softened by tempering caused by heating during the use of a disk brake, can maintain the predetermined hardness, and has excellent punching workability, bending workability before quenching, and a particularly small shear drop, and in which a predetermined hardness after quenching is constantly achieved, in a low carbon martensitic stainless steel sheet used only after quenching. Specifically, the sheet contains, on the basis of mass percent, 0.030% to 0.100% C; 0.50% or less of Si; 1.00% to 2.50% Mn; more than 10.00% to 15.00% Cr; at least one selected from the group consisting-of 0.01% to 0.50% Ti, 0.01% to 0.50% V, 0.01% to 1.00% Nb, and 0.01% to 1.00% Zr; N in an amount defined by the following expression, N: 0.005% to (Ti+V)×{fraction (14/50)}+(Nb+Zr)×{fraction (14/90)}; and the balance being Fe and incidental impurities. The sheet further contains, on the basis of mass percent, more than 0.Type: ApplicationFiled: February 12, 2003Publication date: May 20, 2004Inventors: Yoshihiro Ozaki, Toshimitsu Nagaya, Atsushi Miyazaki, Susumu Satoh, Mineo Muraki, Setsuo Kakihara, Toshihiro Kasamo
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Patent number: 6719855Abstract: The present invention provides an Fe—Cr—Al-based alloy for catalyst carriers and a foil thereof having a thickness of 40 &mgr;m or less, the alloy and the foil improved in the oxidation resistance at high temperatures and having excellent deformation resistance. Specifically, the present invention provides an Fe—Cr—Al-based alloy foil and a manufacturing method thereof, comprising 16.0 to 25.0 mass % of Cr, 1 to 8 mass % of Al, La, Zr, and the balance being Fe and incidental impurities. The contents by mass % of La and Zr meet the following ranges when the foil thickness thereof is t &mgr;m: 1.4/t≦La≦6.0/t (1) 0.6/t≦Zr≦4.0/t (2) The Fe—Cr—Al-based alloy foil may further comprises Hf and the balance being Fe and incidental impurities, wherein the contents by mass % of La, Zr, and Hf meet the following ranges: 1.4/t≦La≦6.0/t (1) 0.4/t≦Zr≦2.0/t (3) 0.5/t≦Hf≦2.0/t (4).Type: GrantFiled: February 27, 2002Date of Patent: April 13, 2004Assignee: JFE Steel CorporationInventors: Kunio Fukuda, Susumu Satoh, Kazuhide Ishii, Takeshi Fujihira, Akira Kawaharada
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Patent number: 6645324Abstract: A ferritic stainless steel plate of excellent ridging resistance and formability, as well as a manufacturing method thereof are proposed. Specifically, the rolling is conducted at a rolling reduction of 30% or more in at least 1 pass and at a temperature difference between the center of the plate thickness and the surface of 200° C. or lower in a pass for the maximum rolling reduction to cause the area ratio of a {111} orientation colony to be present by 30% or more in the regions of ⅛ to ⅜ and ⅝ to ⅞ of the plate thickness. The {111} orientation colony is an assembly of adjacent crystals in which the angle of <111> orientation vector for each of the crystals relative to the direction vector vertical to the rolling surface is within 15°.Type: GrantFiled: March 21, 2002Date of Patent: November 11, 2003Assignee: Kawasaki Steel CorporationInventors: Norimasa Hirata, Takeshi Yokota, Yasushi Kato, Takumi Ujiro, Susumu Satoh
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Publication number: 20030175549Abstract: An alloyed hot-dip galvanized steel sheet is obtained by forming a hot-dip galvanized layer on the surface of the steel sheet and then alloying the steel sheet. The steel sheet exhibits a potential of −850 mV or less when it is immersed in a zinc sulfate-sodium chloride electrolyte. Alternatively, when it is electrolyzed according to constant potential electrolysis process in a zinc sulfate-sodium chloride electrolyte at a potential in a range from −940 mV to −920 mV, the quantity of electricity consumed is less than or equal to 0.5 C/cm2. The steel sheet exhibits excellent processability and particularly excellent sliding property.Type: ApplicationFiled: December 17, 2002Publication date: September 18, 2003Inventors: Kyoko Fujimoto, Makoto Shimura, Yoichi Tobiyama, Susumu Satoh
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Patent number: 6609266Abstract: A wiper motor suitably applied to the wiper apparatus possible to solve a difference in the wiping range caused by the difference in the operation speed of the wiper blade by the wiper linkage used with an eccentric mechanism, which is provided with a semi-ringshaped high-potential plate connected with the power source, a semi-ringshaped low-potential plate grounded and disposed oppositely to the high-potential plate, and a common plate disposed in the center between the high and low-potential plates and electrically connected with the movable contact to rotate slidingly on the high and low-potential plates together with an output shaft of the wiper motor.Type: GrantFiled: June 30, 2000Date of Patent: August 26, 2003Assignee: Jidosha Denki Kogyo Kabushiki KaishaInventors: Susumu Satoh, Hiroyuki Satoh
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Publication number: 20030092182Abstract: A molecule introducing apparatus is provided with a power supply circuit 20 for supplying power, a step-up transformer 30 which is supplied with power from the power supply circuit 20 and which outputs a high voltage, a switching transistor 22 that blocks off and allows the supply of power from the power supply circuit 20 to the step-up transformer 30 and which generates an instantaneous high voltage, and a pair of electrode probes 50 for applying the instantaneous high voltage generated at the step-up transformer 30 to a predetermined region in a body. The molecule introducing apparatus oscillates DNA arranged outside a cell by the instantaneous high voltage so as to introduce the DNA into the cell.Type: ApplicationFiled: November 13, 2002Publication date: May 15, 2003Inventors: Yoshitaka Sakamoto, Masafumi Koide, Juichiro Nakashima, Susumu Satoh, Sousuke Miyoshi, Akiko Suzuki, Hiroyuki Arakawa, Hiroshi Marusawa
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Patent number: RE40950Abstract: The present invention provides a ferritic stainless steel sheet having excellent formability and excellent surface quality after forming. In specific means, the steel sheet contains, by mass %, 0.02 to 0.06% of C, 1.0% or less of Si, 1.0% or less of Mn, 0.05% or less of P, 0.01% or less of S, 0.005% or less of Al, 0.005% or less of Ti, 11 to 30% of Cr, 0.7% or less of Ni, the balance composed of Fe, and inevitable impurities, wherein N is contained to satisfy the relation to the C content represented by 0.06?(C+N)?0.12, and 1?N/C, and V is contained to satisfy the relation to the N content represented by 1.5×10?3?(V×N)?1.5×10?2 (wherein C, N and V: the contents (mass %) of the elements).Type: GrantFiled: March 14, 2000Date of Patent: November 10, 2009Assignee: JFE Steel CorporationInventors: Hiroki Ota, Yasushi Kato, Takumi Ujiro, Susumu Satoh