Patents by Inventor Suyue Qian
Suyue Qian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230165489Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes two or more sensing elements disposed laterally to each other, where the sensing surface is on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: ApplicationFiled: August 26, 2022Publication date: June 1, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Udo HOSS, Phu LE, Yi WANG, Frank David FUJIMOTO, Suyue QIAN, Lam TRAN
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Patent number: 11457840Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes two or more sensing elements disposed laterally to each other, where the sensing surface is on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: GrantFiled: March 20, 2019Date of Patent: October 4, 2022Assignee: Abbott Diabetes Care Inc.Inventors: Udo Hoss, Phu Le, Yi Wang, Frank David Fujimoto, Suyue Qian, Lam Tran
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Publication number: 20220192550Abstract: Analyte sensor comprises an electrode layer having an elongate body comprising a proximal end and a distal end. The electrode layer includes a first active working electrode area, a second electrode portion, and at least one gap electrically separating the first active working electrode portion and the second electrode portion. The first active working electrode area comprises at least one sensing spot with at least one analyte responsive enzyme disposed thereupon. Additional analyte sensors disclosed.Type: ApplicationFiled: June 15, 2021Publication date: June 23, 2022Applicant: ABBOTT DIABETES CARE INC.Inventors: Udo Hoss, Tianmei Ouyang, Benjamin J. Feldman, Suyue Qian
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Publication number: 20210251530Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes an array two or more discontiguous sensing elements deposited on a substrate surface, where the sensing elements comprise one or more droplets of a sensing element formulation.Type: ApplicationFiled: April 14, 2021Publication date: August 19, 2021Applicant: Abbott Diabetes Care Inc.Inventors: Udo Hoss, Phu Le, Yi Wang, Frank David Fujimoto, Suyue Qian, Lam Tran
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Publication number: 20210190719Abstract: Methods and analyte sensors including a sensor tail comprising at least a first working electrode and a second working electrode that are spaced apart from one another along a length of the sensor tail. A first active area is disposed upon a surface of the first working electrode and a second active area is disposed upon a surface of the second working electrode, the first active area and the second active area being responsive to different analytes. A mass transport limiting membrane is deposited upon the first active area and the second active area by sequential dip coating operations, and the mass transport limiting membrane comprises a bilayer membrane portion overcoating the first active area and a homogeneous membrane portion overcoating the second active area.Type: ApplicationFiled: January 18, 2021Publication date: June 24, 2021Applicant: Abbott Diabetes Care Inc.Inventors: John V. LaTour, Jonathan D. McCanless, Stephen Oja, Tianmei Ouyang, Kevin Paul Wallis, Benjamin J. Feldman, Udo Hoss, Suyue Qian
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Publication number: 20210190718Abstract: Analyte sensors responsive at low working electrode potentials may comprise an active area upon a surface of a working electrode, wherein the active area comprises a polymer, a redox mediator covalently bonded to the polymer, and at least one analyte-responsive enzyme covalently bonded to the polymer. A specific redox mediator responsive at low potential may have a structure of wherein G is a linking group covalently bonding the redox mediator to the polymer. A mass transport limiting membrane permeable to the analyte may overcoat the active area. In some sensor configurations, the mass transport limiting membrane may comprise a membrane polymer crosslinked with a branched crosslinker comprising three or more crosslinkable groups, such as polyethylene glycol tetraglycidyl ether.Type: ApplicationFiled: December 23, 2020Publication date: June 24, 2021Applicant: Abbott Diabetes Care Inc.Inventors: John V. LaTour, Jonathan D. McCanless, Stephen Oja, Tianmei Ouyang, Kevin Paul Wallis, Benjamin J. Feldman, Udo Hoss, Suyue Qian
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Patent number: 10859525Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.Type: GrantFiled: April 27, 2018Date of Patent: December 8, 2020Assignee: Abbott Diabetes Care Inc.Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang, Suyue Qian
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Publication number: 20200060592Abstract: It can be particularly difficult to measure pH in vivo using current electrochemical sensors due to sensor drift and fouling of the sensor surface. Sensors suitable for measuring pH, particularly in vivo, may comprise: a sensor tail comprising a first working electrode, a second working electrode, and at least one other electrode; a first active portion located upon the first working electrode, the first active portion comprising a substance having pH-dependent oxidation-reduction chemistry; and a second active portion located upon the second working electrode, the second active portion comprising a substance having oxidation-reduction chemistry that is substantially invariant with pH. A difference between a first signal from the first active portion and a second signal from the second active portion may be correlated to a pH value for a fluid.Type: ApplicationFiled: August 21, 2019Publication date: February 27, 2020Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. Feldman, Suyue Qian
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Publication number: 20190216374Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes two or more sensing elements disposed laterally to each other, where the sensing surface is on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: ApplicationFiled: March 20, 2019Publication date: July 18, 2019Applicant: Abbott Diabetes Care Inc.Inventors: Udo Hoss, Phu Le, Yi Wang, Frank David Fujimoto, Suyue Qian, Lam Tran
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Patent number: 10327677Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes two or more sensing elements disposed laterally to each other, where the sensing surface is on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: GrantFiled: December 8, 2011Date of Patent: June 25, 2019Assignee: Abbott Diabetes Care Inc.Inventors: Udo Hoss, Phu Le, Yi Wang, Frank David Fujimoto, Suyue Qian, Lam Tran
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Publication number: 20180252660Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.Type: ApplicationFiled: April 27, 2018Publication date: September 6, 2018Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang, Suyue Qian
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Patent number: 9983161Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.Type: GrantFiled: November 23, 2016Date of Patent: May 29, 2018Assignee: Abbott Diabetes Care Inc.Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang, Suyue Qian
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Publication number: 20170138886Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.Type: ApplicationFiled: November 23, 2016Publication date: May 18, 2017Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang, Suyue Qian
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Patent number: 9535027Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.Type: GrantFiled: July 24, 2013Date of Patent: January 3, 2017Assignee: Abbott Diabetes Care Inc.Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang, Suyue Qian
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Publication number: 20140026646Abstract: Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.Type: ApplicationFiled: July 24, 2013Publication date: January 30, 2014Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang, Suyue Qian
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Publication number: 20120150005Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes two or more sensing elements disposed laterally to each other, where the sensing surface is on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.Type: ApplicationFiled: December 8, 2011Publication date: June 14, 2012Inventors: Udo Hoss, Phu Le, Yi Wang, Frank David Fujimoto, Suyue Qian, Lam Tran
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Patent number: 7824879Abstract: An assay device and method for determining the concentration of low density lipoprotein (LDL)-associated cholesterol (LDL-C) in a body-fluid sample, such as a blood sample is described.Type: GrantFiled: January 9, 2008Date of Patent: November 2, 2010Assignee: Cholestech CorporationInventors: Shireen Khan, Suyue Qian, Jeff Shindelman, George E. Withers, III, Eileen Gee, William H. Chapman, Jr., Greg Bennett, Thomas D. Schaal
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Publication number: 20080166745Abstract: An assay device and method for determining the concentration of low density lipoprotein (LDL)-associated cholesterol (LDL-C) in a body-fluid sample, such as a blood sample is described.Type: ApplicationFiled: January 9, 2008Publication date: July 10, 2008Applicant: Cholestech CorporationInventors: Shireen Khan, Suyue Qian, Jeff Shindelman, George E. Withers, Eileen Gee, William H. Chapman, Greg Bennett, Thomas D. Schaal
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Patent number: 7238519Abstract: An immunoassay cassette, apparatus, and method for detecting an analyte in a liquid body-fluid sample are disclosed. The cassette has a body and a support mounted on the body, for movement relative to the body to first and second transfer positions. Sample supplied to a sample well in the cassette body is transferred to a reagent reservoir on the cassette body, by moving the support to its first transfer position. Here the sample reacts with a first reagent composition in the reservoir effective to form a modified sample. The modified sample is then transferred to a reagent strip on the support by moving the support to its second transfer position. The reagent strip has a transfer zone at which sample material is transferred to the strip, a second reagent composition effective to react with the modified sample to form a detectable analyte-dependent product, and a detection zone located downstream at which the detectable product can be observed.Type: GrantFiled: December 17, 2004Date of Patent: July 3, 2007Assignee: Cholestech CorporationInventors: Neal F. Bellet, Jeffrey Shindelman, Thomas E. Worthy, Kimberly Haley, Richard K-T Lee, Jane Eunhee Kyung, Suyue Qian
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Patent number: 7186566Abstract: Chromatographic strip is used in combination with a transmittance detecting system in a test to quantitate analytes in biological fluid. Chemical reagents or conjugate labels are simply absorbed on the passages' materials of the strip. The substrates, affinity reagents, or antibodies are immobilized on transparent beads in the detection cell of the strip. The biological fluid passes through the strip. The captured analytes are detected by transmittance detection for quantification. Uncaptured elements and interferences in the fluid are drained to the absorbent portion of the strip when the fluid passes the cell as a wash. This chromatographic strip with an analyte capture zone simplifies the procedures that a transmittance detecting system alone cannot overcome. Adjustable light path of the cells in the strip overcome the sensitivity limitation of reflectance detection.Type: GrantFiled: July 28, 2003Date of Patent: March 6, 2007Inventor: Suyue Qian