Patents by Inventor Suzanne Dagher

Suzanne Dagher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED VASOACTIVE INTESTINAL PEPTIDES
    Publication number: 20240091313
    Abstract: The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.
    Type: Application
    Filed: May 2, 2023
    Publication date: March 21, 2024
    Inventors: Homayoun SADEGHI, Suzanne DAGHER, Andrew TURNER
  • COMPOSITIONS AND METHODS FOR PRODUCING HUMAN MILK OLIGOSACCHARIDES
    Publication number: 20230279368
    Abstract: The present disclosure provides compositions and methods related to the production of human milk oligosaccharides (HMOs). In particular, the present disclosure provides compositions and methods for converting lactose and N-acetylglucosamine (GlcNAc) into N-acetyllactosamine (LacNAc)-enriched galactooligosaccharide (GOS) compositions using novel ?-hexosyl-transferase (BHT) enzymes.
    Type: Application
    Filed: May 18, 2021
    Publication date: September 7, 2023
    Inventors: Jose M. Bruno-Barcena, Suzanne Dagher, Maria Andrea Azcarate-Peril
  • Beta-hexosyl-transferases and uses thereof
    Patent number: 10513695
    Abstract: This invention relates generally to the discovery of novel recombinant forms of ?-hexosyl-transferases (BHT) and uses thereof to produce galacto-oligosaccharides (GOS) or as food additives.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: December 24, 2019
    Assignee: North Carolina State University
    Inventors: Jose M. Bruno-Barcena, Suzanne Dagher, Maria Azcarate-Peril
  • BETA-HEXOSYL-TRANSFERASES AND USES THEREOF
    Publication number: 20180037873
    Abstract: This invention relates generally to the discovery of novel recombinant forms of ?-hexosyl-transferases (BHT) and uses thereof to produce galacto-oligosaccharides (GOS) or as food additives.
    Type: Application
    Filed: September 12, 2017
    Publication date: February 8, 2018
    Inventors: Jose M. Bruno-Barcena, Suzanne Dagher, Maria Azcarate-Peril
  • MODIFIED VASOACTIVE INTESTINAL PEPTIDES
    Publication number: 20180008677
    Abstract: The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.
    Type: Application
    Filed: June 13, 2017
    Publication date: January 11, 2018
    Inventors: Homayoun SADEGHI, Suzanne DAGHER, Andrew TURNER
  • Beta-hexosyl-transferases and uses thereof
    Patent number: 9783789
    Abstract: This invention relates generally to the discovery of novel recombinant forms of ?-hexosyl-transferases (BHT) and uses thereof to produce galacto-ligosaccharides (GOS) or as food additives.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: October 10, 2017
    Assignee: North Carolina State University
    Inventors: Jose M. Bruno-Barcena, Suzanne Dagher, Maria Azcarate-Peril
  • Modified vasoactive intestinal peptides
    Patent number: 9700598
    Abstract: The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: July 11, 2017
    Assignee: PHASEBIO PHARMACEUTICALS, INC.
    Inventors: Homayoun Sadeghi, Suzanne Dagher, Andrew Turner
  • MODIFIED VASOACTIVE INTESTINAL PEPTIDES
    Publication number: 20160220642
    Abstract: The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.
    Type: Application
    Filed: April 8, 2015
    Publication date: August 4, 2016
    Inventors: Homayoun SADEGHI, Suzanne DAGHER, Andrew TURNER
  • BETA-HEXOSYL-TRANSFERASES AND USES THEREOF
    Publication number: 20150307856
    Abstract: This invention relates generally to the discovery of novel recombinant forms of ?-hexosyl-transferases (BHT) and uses thereof to produce galacto-ligosaccharides (GOS) or as food additives.
    Type: Application
    Filed: December 9, 2013
    Publication date: October 29, 2015
    Inventors: Jose M. Bruno-Barcena, Suzanne Dagher, Maria Azcarate-Peril
  • Modified vasoactive intestinal peptides
    Patent number: 9029505
    Abstract: The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.
    Type: Grant
    Filed: August 16, 2010
    Date of Patent: May 12, 2015
    Assignee: Phasebio Pharmaceuticals, Inc.
    Inventors: Homayoun Sadeghi, Suzanne Dagher, Andrew Turner
  • MODIFIED VASOACTIVE INTESTINAL PEPTIDES
    Publication number: 20110178017
    Abstract: The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.
    Type: Application
    Filed: August 16, 2010
    Publication date: July 21, 2011
    Applicant: PhaseBio Pharmaceuticals, Inc.
    Inventors: Homayoun Sadeghi, Suzanne Dagher, Andrew Turner
  • MULTIMERIC ELP FUSION CONSTRUCTS
    Publication number: 20110082283
    Abstract: ELP fusion proteins, multimeric ELP spider complexes formed of ELP fusion proteins, and methods of using the same. The construct may be in the form of an ELP spider structure complex including multi-leg moieties comprising ELP fusion proteins capable of forming covalent disulfide bonds. The multimeric fusion constructs may be employed in peptide production and purification and/or to enhance proteolytic resistance of a protein or peptide moiety in a fusion construct, by provision of the fusion protein in an ELP spider complex.
    Type: Application
    Filed: February 25, 2010
    Publication date: April 7, 2011
    Inventor: Suzanne DAGHER
  • Multimeric ELP fusion constructs
    Patent number: 7709227
    Abstract: ELP fusion proteins, multimeric ELP spider complexes formed of ELP fusion proteins, and methods of using the same. The construct may be in the form of an ELP spider structure complex including multi-leg moieties comprising ELP fusion proteins capable of forming covalent disulfide bonds. The multimeric fusion constructs may be employed in peptide production and purification and/or to enhance protelytic resistance of a protein or peptide moiety in a fusion construct, by provision of the fusion protein in an ELP spider complex.
    Type: Grant
    Filed: January 4, 2007
    Date of Patent: May 4, 2010
    Assignee: PhaseBio Pharmaceuticals, Inc.
    Inventor: Suzanne Dagher
  • MULTIMERIC ELP FUSION CONSTRUCTS
    Publication number: 20080032400
    Abstract: ELP fusion proteins, multimeric ELP spider complexes formed of ELP fusion proteins, and methods of using the same. The construct may be in the form of an ELP spider structure complex including multi-leg moieties comprising ELP fusion proteins capable of forming covalent disulfide bonds. The multimeric fusion constructs may be employed in peptide production and purification and/or to enhance protelytic resistance of a protein or peptide moiety in a fusion construct, by provision of the fusion protein in an ELP spider complex.
    Type: Application
    Filed: January 4, 2007
    Publication date: February 7, 2008
    Inventor: Suzanne Dagher
  • Beta-hexosyl-transferases and uses thereof
    Patent number: RE49936
    Abstract: This invention relates generally to the discovery of novel recombinant forms of ?-hexosyl-transferases (BHT) and uses thereof to produce galacto-oligosaccharides (GOS) or as food additives.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: April 23, 2024
    Assignee: North Carolina State University
    Inventors: Jose M. Bruno-Barcena, Suzanne Dagher, Maria Azcarate-Peril