Abstract: A computing system (118) includes a computer readable storage medium (122) with computer executable instructions (124), including: a biophysical simulator (126) configured to simulate coronary or carotid flow and pressure effects induced by a cardiac valve device implantation, using cardiac image data and a device model (212). The computing system further includes a processor (120) configured to execute the biophysical simulator to simulate the coronary or carotid flow and the pressure effects induced by the device implantation with the cardiac image data and the device model. The computing system further includes a display configured to display results of the simulation.

Abstract: A computing system (118) includes a computer readable storage medium (122) with computer executable instructions (124), including a biophysical simulator (126) and an electrocardiogram signal analyzer (128). The computing system further includes a processor (120) configured to execute the electrocardiogram signal analyzer determine myocardial infarction characteristics from an input electrocardiogram and to execute the biophysical simulator to simulate a fractional flow reserve or an instant wave-free ratio index from input cardiac image data and the determined myocardial infarction characteristics.

Abstract: The invention relates to a navigation system for navigating an interventional device (11) like a catheter and an interventional system comprising the navigation system. A position and shape determining unit (13) determines and stores a first position and shape of the interventional device within a living being (9) during a first interventional procedure like a first chemoembolization session and determines a second position and shape of an interventional device within the living being during a subsequent second interventional procedure like a second chemoembolization session. During the second interventional procedure the interventional device is navigated based on the stored first position and shape and based on the second position and shape. This allows considering during the second interventional procedure the path of the interventional device used during the first interventional procedure.

Abstract: An imaging system (500) includes a data acquisition system (515) configured to produce projection data and at least one memory device with reconstruction algorithms (518) and at least one blending algorithm (524). The imaging system further includes a reconstructor (516) configured to reconstruct the projection data with the reconstruction algorithms and generate at least first spectral volumetric image data corresponding to a first basis material content and second spectral volumetric image data corresponding to a second basis material content, and blend the first spectral volumetric image data and the second spectral volumetric image data with the at least one blending algorithm to produce blended volumetric image data.

Abstract: The present disclosure relates to a method for controlling a magnetic resonance imaging guided radiation therapy apparatus comprising a magnetic resonance imaging system.

Abstract: An imaging system (500) includes a data acquisition system (515) configured to produce projection data and at least one memory device with reconstruction algorithms (518) and at least one blending algorithm (524). The imaging system further includes a reconstructor (516) configured to reconstruct the projection data with the reconstruction algorithms and generate at least first spectral volumetric image data corresponding to a first basis material content and second spectral volumetric image data corresponding to a second basis material content, and blend the first spectral volumetric image data and the second spectral volumetric image data with the at least one blending algorithm to produce blended volumetric image data.

Abstract: A computing system (126) includes a computer readable storage medium (130) with computer executable instructions (128), including: a segmentation standardizer (120) configured to determine a standardized vascular tree from a segmented vascular tree segmented of volumetric image data and a predetermined set of pruning rules (206), and a biophysical simulator (122) configured to perform a biophysical simulation based on the standardized vascular tree. The computing system further includes a processor (124) configured to execute the segmentation standardizer to determine the standardized vascular tree from the segmented vascular tree segmented of volumetric image data and the predetermined set of pruning rules, and configured to execute the biophysical simulator to perform a biophysical simulation based on the standardized vascular tree. The computing system further includes a display configured to display at least one of the standardized vascular tree and a result of the biophysical simulation.

Abstract: A computing system (118) includes a computer readable storage medium (122) with computer executable instructions (124), including a biophysical simulator (126) and an electrocardiogram signal analyzer (128). The computing system further includes a processor (120) configured to execute the electrocardiogram signal analyzer determine myocardial infarction characteristics from an input electrocardiogram and to execute the biophysical simulator to simulate a fractional flow reserve or an instant wave-free ratio index from input cardiac image data and the determined myocardial infarction characteristics.

Abstract: A computing system (118) includes a computer readable storage medium (122) with computer executable instructions (124), including: a biophysical simulator (126) configured to simulate coronary or carotid flow and pressure effects induced by a cardiac valve device implantation, using cardiac image data and a device model (212). The computing system further includes a processor (120) configured to execute the biophysical simulator to simulate the coronary or carotid flow and the pressure effects induced by the device implantation with the cardiac image data and the device model. The computing system further includes a display configured to display results of the simulation.

Abstract: Stenosis information is obtained by obtaining photographic image data (302) from a displayed image of a blood vessel (103, 203) containing the stenosis. Contours of the blood vessel and the stenosis are detected and dimensions are estimated from the photographic image data. A blood vessel model is reconstructed and fractional flow reserve data is calculated using the blood vessel model.

Abstract: The present invention teaches a method and system for computing an alternative electron density map of an examination volume. The processing system is configured to compute a first electron density map using a plurality of imaging data, compute a second electron density map, wherein the second electron density map is a simplified version of the first electron density map, and compute the alternative electron density map, using the first electron density map and the second electron density map.

Abstract: The invention relates to a system and a method for guiding an intravascular ultrasound catheter device comprising an ultrasound probe to a potential lesion in a vascular tree (31). In the system, position information of the probe are provided for displaying to a user and/or for an automated processing of the position information. An evaluation unit is configured to receive a diagnostic image of the vascular tree, to determine values of at least one vessel parameter for a plurality of locations in the vascular tree, and to identify at least one location associated with an abnormal value of the at least one vessel parameter. Further, a mapping unit is configured to provide a visual indication (32) of the at least one location in the visualization of the vascular tree and/or to provide information about the at least one location for use in the automated processing of the position information.

Abstract: Patient-specific prosthetic apparatus and methods. The patient-specific prosthetic apparatus includes a prosthetic device and a prosthetic adapter configured to be secured with the prosthetic device, wherein the prosthetic adapter includes an interior surface that matches the shape of a portion of the prosthetic device, and an exterior surface that matches a patient's anatomy.

Abstract: A computing system (126) includes a computer readable storage medium (130) with computer executable instructions (128), including: a segmentation standardizer (120) configured to determine a standardized vascular tree from a segmented vascular tree segmented of volumetric image data and a predetermined set of pruning rules (206), and a biophysical simulator (122) configured to perform a biophysical simulation based on the standardized vascular tree. The computing system further includes a processor (124) configured to execute the segmentation standardizer to determine the standardized vascular tree from the segmented vascular tree segmented of volumetric image data and the predetermined set of pruning rules, and configured to execute the biophysical simulator to perform a biophysical simulation based on the standardized vascular tree. The computing system further includes a display configured to display at least one of the standardized vascular tree and a result of the biophysical simulation.

Abstract: The invention relates to an apparatus for determining a fractional flow reserve (FFR) value of the coronary artery system of a living being (3). A fractional flow reserve value determination unit (13) determines the FFR value by using an FFR value determination algorithm that is adapted to determine the FFR value based on a boundary condition and a provided representation of the coronary artery system, wherein the boundary condition is specific for the living being and determined by a boundary condition determination unit (12). Since the boundary condition determination unit determines a boundary condition, which is specific for the living being, and since the fractional flow reserve value determination unit not only uses the provided representation of the coronary artery system, but also the living being specific boundary condition for determining the FFR value, the accuracy of the FFR value, which is non-invasively determined, can be improved.

Abstract: The present invention relates a calculation device for superimposing a laparoscopic image and an ultrasound image. The calculation device is configured for receiving a laparoscopic image, an ultrasound image and a depth image of a depth-sensing device. The calculation device extracts depth cue information from the depth image and uses the extracted depth cue information for superimposing the laparoscopic image and the ultrasound image thereby generating a superimposed image. The calculation device may use the spatial position and orientation of both the laparoscope and the ultrasound device to spatially co-register the devices relative to each other. This can then be used to present a correctly superimposed view rendering of both laparoscope and ultrasound image data. This merged view greatly facilitates the user in locating and positioning the ultrasound probe and the location of interest. In one embodiment, the surface of the object of interest is measured and virtually cut along the ultrasound plane.

Abstract: Stenosis information is obtained by obtaining photographic image data (302) from a displayed image of a blood vessel (103, 203) containing the stenosis. Contours of the blood vessel and the stenosis are detected and dimensions are estimated from the photographic image data. A blood vessel model is reconstructed and fractional flow reserve data is calculated using the blood vessel model.

Abstract: A system (100) for a targeted perfusion scan includes a computed tomography (CT) scanner (120), a feeding territory map (132) and a targeted perfusion unit (140). The CT scanner (120) performs a perfusion scan of a portion of tissues of an organ. The feeding territory map (132) maps arterial locations of an arterial vessel tree to spatially located organ tissues of the organ fed by the arterial locations. The targeted perfusion unit (140) includes one or more processors (164) configured to determine targeted coverage (200) from a location of a stenosis (112, 210) and the feeding territory map, and to control the CT scanner to perform the perfusion scan according to the determined targeted coverage.

Abstract: The present disclosure relates to a method for controlling a magnetic resonance imaging guided radiation therapy apparatus comprising a magnetic resonance imaging system.

Abstract: The present invention teaches a method and system for computing an alternative electron density map of an examination volume. The processing system is configured to compute a first electron density map using a plurality of imaging data, compute a second electron density map, wherein the second electron density map is a simplified version of the first electron density map, and compute the alternative electron density map, using the first electron density map and the second electron density map.